Featured Research

from universities, journals, and other organizations

MRSA may increase mortality rate by 50 percent, study finds

Date:
September 10, 2011
Source:
Linkoeping Universitet
Summary:
Does the Methicillin-resistant Staphylococcus aureus, MRSA, cause more deaths in hospitals than the bacteria that are sensitive to common antibiotics? Opinions have been varied, but now a worldwide study indicates that the mortality rate can be 50 percent higher for intensive care patients infected with MRSA.

Does the Methicillin-resistant Staphylococcus aureus, MRSA, cause more deaths in hospitals than the bacteria that are sensitive to common antibiotics? Opinions have been varied, but now a worldwide study at, among others, Linköping University in Sweden, indicates that the mortality rate can be 50 percent higher for intensive care patients infected with MRSA.

Golden staph (Staphylococcus aureus) is a common cause of infections in patients in intensive care and in many countries often methicillin-resistant, i.e. it is resistant to most staphylococcus antibiotics. Only a few, very expensive antibiotics remain and they produce challenging side effects. The infection is easily transmitted in hospital settings where many patients are especially vulnerable to infection.

However whether or not MRSA retains an increased mortality rate in patients has been a controversial point. Now, Håkan Hanberger, Professor of Infectious Diseases at Linköping University, has published a study conducted in 75 countries that delivers an unequivocal result: Intensive care patients who received treatment for an infection caused by golden staph 50% increased risk for fatality if the bacterium is resistant.

"The study also shows that every second staph was resistant to the golden staph penicillin which remains the standard treatment in the Swedish health care," says Håkan Hanberger.

Hanberger is principal author of the article published in the International Journal of Antimicrobial Agents, and is now available on the journal's Web edition.

The study, entitled EPIC II, was conducted on May 8, 2007 at 1265 intensive care units In 75 countries in 13,796 hospitalized patients. Over half of the patients had some kind of infection: 999 patients were infected with Staphylococcus aureus including 494 with MRSA. The subjects were reassessed 60 days later.

Patients infected with MRSA were slightly older than the others in the group and to a greater extent, suffered from cancer and chronic renal failure. However once the results were adjusted for these and other factors in the so-called multivariate analysis, it became evident that infections with resistant staphylococci accounted for nearly a 50% increase in mortality.

There was considerable variation among patients from different geographical regions.

"In Sweden, the incidence of MRSA remains low, less than 5%. Therefore it is very important that patients infected with staphylococci are isolated and screened in order to prevent the spread of the disease," says Håkan Hanberger.


Story Source:

The above story is based on materials provided by Linkoeping Universitet. Note: Materials may be edited for content and length.


Journal Reference:

  1. Hanberger H, et al. Increased mortality associated with meticillin-resistant Staphylococcus aureus (MRSA) infection in the Intensive Care Unit: results from the EPIC II study. International Journal of Antimicrobial Agents, 2011 DOI: 10.1016/j.ijantimicag.2011.05.013

Cite This Page:

Linkoeping Universitet. "MRSA may increase mortality rate by 50 percent, study finds." ScienceDaily. ScienceDaily, 10 September 2011. <www.sciencedaily.com/releases/2011/08/110824115846.htm>.
Linkoeping Universitet. (2011, September 10). MRSA may increase mortality rate by 50 percent, study finds. ScienceDaily. Retrieved July 25, 2014 from www.sciencedaily.com/releases/2011/08/110824115846.htm
Linkoeping Universitet. "MRSA may increase mortality rate by 50 percent, study finds." ScienceDaily. www.sciencedaily.com/releases/2011/08/110824115846.htm (accessed July 25, 2014).

Share This




More Health & Medicine News

Friday, July 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

New Painkiller Designed To Discourage Abuse: Will It Work?

New Painkiller Designed To Discourage Abuse: Will It Work?

Newsy (July 24, 2014) — The FDA approved Targiniq ER on Wednesday, a painkiller designed to keep users from abusing it. Like any new medication, however, it has doubters. Video provided by Newsy
Powered by NewsLook.com
Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Newsy (July 24, 2014) — Sheik Umar Khan has treated many of the people infected in the Ebola outbreak, and now he's become one of them. Video provided by Newsy
Powered by NewsLook.com
Condemned Man's US Execution Takes Nearly Two Hours

Condemned Man's US Execution Takes Nearly Two Hours

AFP (July 24, 2014) — America's death penalty debate raged Thursday after it took nearly two hours for Arizona to execute a prisoner who lost a Supreme Court battle challenging the experimental lethal drug cocktail. Duration: 00:55 Video provided by AFP
Powered by NewsLook.com
Can Watching TV Make You Feel Like A Failure?

Can Watching TV Make You Feel Like A Failure?

Newsy (July 24, 2014) — A study by German researchers claims watching TV while you're stressed out can make you feel guilty and like a failure. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

    Health News

      Environment News

        Technology News



          Save/Print:
          Share:  

          Free Subscriptions


          Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

          Get Social & Mobile


          Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

          Have Feedback?


          Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
          Mobile iPhone Android Web
          Follow Facebook Twitter Google+
          Subscribe RSS Feeds Email Newsletters
          Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins