Featured Research

from universities, journals, and other organizations

MRSA may increase mortality rate by 50 percent, study finds

Date:
September 10, 2011
Source:
Linkoeping Universitet
Summary:
Does the Methicillin-resistant Staphylococcus aureus, MRSA, cause more deaths in hospitals than the bacteria that are sensitive to common antibiotics? Opinions have been varied, but now a worldwide study indicates that the mortality rate can be 50 percent higher for intensive care patients infected with MRSA.

Does the Methicillin-resistant Staphylococcus aureus, MRSA, cause more deaths in hospitals than the bacteria that are sensitive to common antibiotics? Opinions have been varied, but now a worldwide study at, among others, Linköping University in Sweden, indicates that the mortality rate can be 50 percent higher for intensive care patients infected with MRSA.

Golden staph (Staphylococcus aureus) is a common cause of infections in patients in intensive care and in many countries often methicillin-resistant, i.e. it is resistant to most staphylococcus antibiotics. Only a few, very expensive antibiotics remain and they produce challenging side effects. The infection is easily transmitted in hospital settings where many patients are especially vulnerable to infection.

However whether or not MRSA retains an increased mortality rate in patients has been a controversial point. Now, Håkan Hanberger, Professor of Infectious Diseases at Linköping University, has published a study conducted in 75 countries that delivers an unequivocal result: Intensive care patients who received treatment for an infection caused by golden staph 50% increased risk for fatality if the bacterium is resistant.

"The study also shows that every second staph was resistant to the golden staph penicillin which remains the standard treatment in the Swedish health care," says Håkan Hanberger.

Hanberger is principal author of the article published in the International Journal of Antimicrobial Agents, and is now available on the journal's Web edition.

The study, entitled EPIC II, was conducted on May 8, 2007 at 1265 intensive care units In 75 countries in 13,796 hospitalized patients. Over half of the patients had some kind of infection: 999 patients were infected with Staphylococcus aureus including 494 with MRSA. The subjects were reassessed 60 days later.

Patients infected with MRSA were slightly older than the others in the group and to a greater extent, suffered from cancer and chronic renal failure. However once the results were adjusted for these and other factors in the so-called multivariate analysis, it became evident that infections with resistant staphylococci accounted for nearly a 50% increase in mortality.

There was considerable variation among patients from different geographical regions.

"In Sweden, the incidence of MRSA remains low, less than 5%. Therefore it is very important that patients infected with staphylococci are isolated and screened in order to prevent the spread of the disease," says Håkan Hanberger.


Story Source:

The above story is based on materials provided by Linkoeping Universitet. Note: Materials may be edited for content and length.


Journal Reference:

  1. Hanberger H, et al. Increased mortality associated with meticillin-resistant Staphylococcus aureus (MRSA) infection in the Intensive Care Unit: results from the EPIC II study. International Journal of Antimicrobial Agents, 2011 DOI: 10.1016/j.ijantimicag.2011.05.013

Cite This Page:

Linkoeping Universitet. "MRSA may increase mortality rate by 50 percent, study finds." ScienceDaily. ScienceDaily, 10 September 2011. <www.sciencedaily.com/releases/2011/08/110824115846.htm>.
Linkoeping Universitet. (2011, September 10). MRSA may increase mortality rate by 50 percent, study finds. ScienceDaily. Retrieved April 19, 2014 from www.sciencedaily.com/releases/2011/08/110824115846.htm
Linkoeping Universitet. "MRSA may increase mortality rate by 50 percent, study finds." ScienceDaily. www.sciencedaily.com/releases/2011/08/110824115846.htm (accessed April 19, 2014).

Share This



More Health & Medicine News

Saturday, April 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

'Holy Grail' Of Weight Loss? New Find Could Be It

'Holy Grail' Of Weight Loss? New Find Could Be It

Newsy (Apr. 18, 2014) — In a potential breakthrough for future obesity treatments, scientists have used MRI scans to pinpoint brown fat in a living adult for the first time. Video provided by Newsy
Powered by NewsLook.com
Little Progress Made In Fighting Food Poisoning, CDC Says

Little Progress Made In Fighting Food Poisoning, CDC Says

Newsy (Apr. 18, 2014) — A new report shows rates of two foodborne infections increased in the U.S. in recent years, while salmonella actually dropped 9 percent. Video provided by Newsy
Powered by NewsLook.com
Scientists Create Stem Cells From Adult Skin Cells

Scientists Create Stem Cells From Adult Skin Cells

Newsy (Apr. 17, 2014) — The breakthrough could mean a cure for some serious diseases and even the possibility of human cloning, but it's all still a way off. Video provided by Newsy
Powered by NewsLook.com
Obama: 8 Million Healthcare Signups

Obama: 8 Million Healthcare Signups

AP (Apr. 17, 2014) — President Barack Obama gave a briefing Thursday announcing 8 million people have signed up under the Affordable Care Act. He blasted continued Republican efforts to repeal the law. (April 17) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins