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Heat in chili peppers can ease sinus problems, research shows

Date:
August 26, 2011
Source:
University of Cincinnati Academic Health Center
Summary:
Hot chili peppers are known to make people "tear up," but a new study found that a nasal spray containing an ingredient derived from hot chili peppers may help people "clear up" certain types of sinus inflammation.

Capsaicin, the main component of chili peppers, may help patients with a number of ailments.
Credit: David Wood / Fotolia

Hot chili peppers are known to make people "tear up," but a new study led by University of Cincinnati allergy researcher Jonathan Bernstein, MD, found that a nasal spray containing an ingredient derived from hot chili peppers (Capsicum annum) may help people "clear up" certain types of sinus inflammation.

The study, which appears in the August 2011 edition of Annals of Allergy, Asthma & Immunology, compares the use of the Capsicum annum nasal spray to a placebo nasal spray in 44 subjects with a significant component of nonallergic rhinitis (i.e., nasal congestion, sinus pain, sinus pressure) for a period of two weeks.

Capsicum annum contains capsaicin, which is the main component of chili peppers and produces a hot sensation. Capsaicin is also the active ingredient in several topical medications used for temporary pain relief. It is approved for use by the U.S. Food and Drug Administration and is available over the counter.

"Basically, we concluded that the spray was safe and effective on non-allergic rhinitis," Bernstein says of the study which showed that participants who used a nasal spray with Capsicum reported a faster onset of action or relief, on average within a minute of using the spray, than the control group.

Non-allergic rhinitis is an upper respiratory condition not caused by allergies but instead caused by environmental factors such as weather, household chemicals or perfumes; however, there are some people who have no triggers or don't know what triggers are causing the inflammation, Bernstein says.

This is the first controlled trial where capsaicin was able to be used on a continuous basis to control symptoms. It is considered a significant advance, "because we don't really have good therapies for non-allergic rhinitis," says Bernstein, adding that in previous trials the ingredient was too hot to administer without anesthesia.

The study was funded by Dynova Laboratories. Bernstein, a professor in the division of immunology, allergy and rheumatology at the UC College of Medicine, is a paid consultant for Dynova.


Story Source:

The above story is based on materials provided by University of Cincinnati Academic Health Center. Note: Materials may be edited for content and length.


Journal Reference:

  1. Jonathan A. Bernstein, Benjamin P. Davis, Jillian K. Picard, Jennifer P. Cooper, Shu Zheng, Linda S. Levin. A randomized, double-blind, parallel trial comparing capsaicin nasal spray with placebo in subjects with a significant component of nonallergic rhinitis. Annals of Allergy, Asthma & Immunology, 2011; 107 (2): 171 DOI: 10.1016/j.anai.2011.05.016

Cite This Page:

University of Cincinnati Academic Health Center. "Heat in chili peppers can ease sinus problems, research shows." ScienceDaily. ScienceDaily, 26 August 2011. <www.sciencedaily.com/releases/2011/08/110825164933.htm>.
University of Cincinnati Academic Health Center. (2011, August 26). Heat in chili peppers can ease sinus problems, research shows. ScienceDaily. Retrieved September 30, 2014 from www.sciencedaily.com/releases/2011/08/110825164933.htm
University of Cincinnati Academic Health Center. "Heat in chili peppers can ease sinus problems, research shows." ScienceDaily. www.sciencedaily.com/releases/2011/08/110825164933.htm (accessed September 30, 2014).

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