Featured Research

from universities, journals, and other organizations

IUD reduces the risk of cervical cancer, study suggests

Date:
September 14, 2011
Source:
IDIBELL-Bellvitge Biomedical Research Institute
Summary:
Intrauterine devices (IUDs) may protect against cervical cancer. This is the conclusion of the broadest epidemiological study to date on the topic.

Intrauterine devices (IUDs) may protect against cervical cancer. This is the conclusion of the broadest epidemiological study to date in which has participated the research group in Viruses and Cancer of IDIBELL, published at The Lancet Oncology.

Related Articles


The results show that women who use IUD halved the risk of developing cervical cancer compared to those that had never used an IUD. These results are contrary to popular belief that IUD could be a risk factor of cervical cancer. Previous studies on possible effects of IUDs use on the development of this cancer have yielded inconsistent results.

To assess the effects of IUD use on the risk of cervical human papillomavirus (HPV) infection and the risk of developing cervical cancer, Xavier Castellsagué, researcher of Virus and Cancer research group at IDIBELL and of the Cancer Epidemiological Research Program at the Catalan Institute of Oncology (ICO), and colleagues analysed data from ten case-control studies of cervical cancer done in eight countries, and 16 HPV prevalence surveys in women from 4 continents.

Findings were adjusted for confounding factors such as number of Papanicolaou (Pap) smears, number of sexual partners, and age at first intercourse, among others.

Reduces the risk by half

IUD use did not affect the risk of HPV infection, but was associated with a significantly lower risk of cervical cancer for both major cervical cancer types -- reducing the likelihood of developing squamous-cell carcinoma by 44% and adenocarcinoma or adenosquamous carcinoma by 54%.

Interestingly, the length of IUD use did not significantly alter cervical cancer risk. The risk was reduced by nearly half in the first year of use and the protective effect remained significant even after 10 years of use.

The authors say that "the associations found in our study strongly suggest that IUD use does not modify the likelihood of prevalent HPV infection [the cause of cervical cancer], but might affect the likelihood of HPV progression to cervical cancer."

They suggest a number of possible explanations for the protective effect of IUDs including that the process of device insertion or removal may destroy precancerous lesions or that it may induce chronic mucosal inflammation and a long lasting immune response, thereby reducing the likelihood of HPV progression.


Story Source:

The above story is based on materials provided by IDIBELL-Bellvitge Biomedical Research Institute. Note: Materials may be edited for content and length.


Journal Reference:

  1. Xavier Castellsagué, Mireia Díaz, Salvatore Vaccarella, Silvia de Sanjosé, Nubia Muñoz, Rolando Herrero, Silvia Franceschi, Chris J L M Meijer, F Xavier Bosch. Intrauterine device use, cervical infection with human papillomavirus, and risk of cervical cancer: a pooled analysis of 26 epidemiological studies. The Lancet Oncology, 2011; DOI: 10.1016/S1470-2045(11)70223-6

Cite This Page:

IDIBELL-Bellvitge Biomedical Research Institute. "IUD reduces the risk of cervical cancer, study suggests." ScienceDaily. ScienceDaily, 14 September 2011. <www.sciencedaily.com/releases/2011/09/110913103100.htm>.
IDIBELL-Bellvitge Biomedical Research Institute. (2011, September 14). IUD reduces the risk of cervical cancer, study suggests. ScienceDaily. Retrieved December 19, 2014 from www.sciencedaily.com/releases/2011/09/110913103100.htm
IDIBELL-Bellvitge Biomedical Research Institute. "IUD reduces the risk of cervical cancer, study suggests." ScienceDaily. www.sciencedaily.com/releases/2011/09/110913103100.htm (accessed December 19, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, December 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Kids Die While Under Protective Services

Kids Die While Under Protective Services

AP (Dec. 18, 2014) — As part of a six-month investigation of child maltreatment deaths, the AP found that hundreds of deaths from horrific abuse and neglect could have been prevented. AP's Haven Daley reports. (Dec. 18) Video provided by AP
Powered by NewsLook.com
Dads-To-Be Also Experience Hormone Changes During Pregnancy

Dads-To-Be Also Experience Hormone Changes During Pregnancy

Newsy (Dec. 18, 2014) — A study from University of Michigan researchers found that expectant fathers see a decrease in testosterone as the baby's birth draws near. Video provided by Newsy
Powered by NewsLook.com
Prenatal Exposure To Pollution Might Increase Autism Risk

Prenatal Exposure To Pollution Might Increase Autism Risk

Newsy (Dec. 18, 2014) — Harvard researchers found children whose mothers were exposed to high pollution levels in the third trimester were twice as likely to develop autism. Video provided by Newsy
Powered by NewsLook.com
UN: Up to One Million Facing Hunger in Ebola-Hit Countries

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

AFP (Dec. 17, 2014) — Border closures, quarantines and crop losses in West African nations battling the Ebola virus could lead to as many as one million people going hungry, UN food agencies said on Wednesday. Duration: 00:52 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins