Featured Research

from universities, journals, and other organizations

IUD reduces the risk of cervical cancer, study suggests

Date:
September 14, 2011
Source:
IDIBELL-Bellvitge Biomedical Research Institute
Summary:
Intrauterine devices (IUDs) may protect against cervical cancer. This is the conclusion of the broadest epidemiological study to date on the topic.

Intrauterine devices (IUDs) may protect against cervical cancer. This is the conclusion of the broadest epidemiological study to date in which has participated the research group in Viruses and Cancer of IDIBELL, published at The Lancet Oncology.

The results show that women who use IUD halved the risk of developing cervical cancer compared to those that had never used an IUD. These results are contrary to popular belief that IUD could be a risk factor of cervical cancer. Previous studies on possible effects of IUDs use on the development of this cancer have yielded inconsistent results.

To assess the effects of IUD use on the risk of cervical human papillomavirus (HPV) infection and the risk of developing cervical cancer, Xavier Castellsagué, researcher of Virus and Cancer research group at IDIBELL and of the Cancer Epidemiological Research Program at the Catalan Institute of Oncology (ICO), and colleagues analysed data from ten case-control studies of cervical cancer done in eight countries, and 16 HPV prevalence surveys in women from 4 continents.

Findings were adjusted for confounding factors such as number of Papanicolaou (Pap) smears, number of sexual partners, and age at first intercourse, among others.

Reduces the risk by half

IUD use did not affect the risk of HPV infection, but was associated with a significantly lower risk of cervical cancer for both major cervical cancer types -- reducing the likelihood of developing squamous-cell carcinoma by 44% and adenocarcinoma or adenosquamous carcinoma by 54%.

Interestingly, the length of IUD use did not significantly alter cervical cancer risk. The risk was reduced by nearly half in the first year of use and the protective effect remained significant even after 10 years of use.

The authors say that "the associations found in our study strongly suggest that IUD use does not modify the likelihood of prevalent HPV infection [the cause of cervical cancer], but might affect the likelihood of HPV progression to cervical cancer."

They suggest a number of possible explanations for the protective effect of IUDs including that the process of device insertion or removal may destroy precancerous lesions or that it may induce chronic mucosal inflammation and a long lasting immune response, thereby reducing the likelihood of HPV progression.


Story Source:

The above story is based on materials provided by IDIBELL-Bellvitge Biomedical Research Institute. Note: Materials may be edited for content and length.


Journal Reference:

  1. Xavier Castellsagué, Mireia Díaz, Salvatore Vaccarella, Silvia de Sanjosé, Nubia Muñoz, Rolando Herrero, Silvia Franceschi, Chris J L M Meijer, F Xavier Bosch. Intrauterine device use, cervical infection with human papillomavirus, and risk of cervical cancer: a pooled analysis of 26 epidemiological studies. The Lancet Oncology, 2011; DOI: 10.1016/S1470-2045(11)70223-6

Cite This Page:

IDIBELL-Bellvitge Biomedical Research Institute. "IUD reduces the risk of cervical cancer, study suggests." ScienceDaily. ScienceDaily, 14 September 2011. <www.sciencedaily.com/releases/2011/09/110913103100.htm>.
IDIBELL-Bellvitge Biomedical Research Institute. (2011, September 14). IUD reduces the risk of cervical cancer, study suggests. ScienceDaily. Retrieved October 23, 2014 from www.sciencedaily.com/releases/2011/09/110913103100.htm
IDIBELL-Bellvitge Biomedical Research Institute. "IUD reduces the risk of cervical cancer, study suggests." ScienceDaily. www.sciencedaily.com/releases/2011/09/110913103100.htm (accessed October 23, 2014).

Share This



More Health & Medicine News

Thursday, October 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Fears Keep Guinea Hospitals Empty

Ebola Fears Keep Guinea Hospitals Empty

AP (Oct. 23, 2014) — Fears of Ebola are keeping doctors and patients alike away from hospitals in the West African nation of Guinea. (Oct. 23) Video provided by AP
Powered by NewsLook.com
Orthodontist Mom Jennifer Salzer on the Best Time for Braces

Orthodontist Mom Jennifer Salzer on the Best Time for Braces

Working Mother (Oct. 22, 2014) — Is your child ready? Video provided by Working Mother
Powered by NewsLook.com
U.S. Issues Ebola Travel Restrictions, Are Visa Bans Next?

U.S. Issues Ebola Travel Restrictions, Are Visa Bans Next?

Newsy (Oct. 22, 2014) — Now that the U.S. is restricting travel from West Africa, some are dropping questions about a travel ban and instead asking about visa bans. Video provided by Newsy
Powered by NewsLook.com
More People Diagnosed With TB In 2013, But There's Good News

More People Diagnosed With TB In 2013, But There's Good News

Newsy (Oct. 22, 2014) — The World Health Organizations says TB numbers rose in 2013, but it's partly due to better detection and more survivors. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins