Featured Research

from universities, journals, and other organizations

Mapping immune genes in salmon

Date:
October 3, 2011
Source:
Norwegian School of Veterinary Science
Summary:
Scientists have identified and mapped a group of immune genes that are the key to warding off infectious agents such as viruses and bacteria in salmon.

Morten F. Lukacs' doctoral research at The Norwegian School of Veterinary Science has identified and mapped a group of immune genes that are the key to warding off infectious agents such as viruses and bacteria in salmon.

The Norwegian fish farming industry is continually growing and the production of Atlantic salmon is one of the country's flagships. One of the problems facing the industry is the threat from viral diseases and parasites, and it is difficult to find effective vaccines against these. But by increasing our knowledge of how salmon defend themselves against bacteria and viruses, we can develop better vaccines and breeding tools.

Salmon have an immune defence system designed to combat both bacterial and viral diseases, but we still do not know exactly how it works. One group of genes, called MHC, which can be found in everything from sharks to humans, is known to affect the development of diseases, such as diabetes in humans and viral infections in chickens. Earlier studies have also shown that in salmon, these genes affect the ability of the fish to withstand viruses and bacteria. In order to discover whether these effects are due to MHC or to closely linked genes, Lukacs carried out a characterization of the areas of DNA where MHC genes are localised in Atlantic salmon.

Through his research, Lukacs has shown that most of the MHC class I genes are to be found in two duplicated areas which have undergone an extensive reshuffling, compared to those of the rainbow trout. These two species of fish are very closely related in their development, but they react differently to, for example, various kinds of viruses.

By mapping the genes, Lukacs found 16 MHC genes, of which many may have new and interesting functions. The overall results of this doctoral research provide a solid platform for the understanding of MHC genes in salmon and for further studies of how these genes affect the fish's defence system against infectious agents.

Cand.scient. Morten F. Lukacs defended his doctoral thesis on 29th September 2011 at The Norwegian School of Veterinary Science. The thesis is entitled: "Characterization of Major Histocompatibility Complex Class I and II Regions in Atlantic Salmon."


Story Source:

The above story is based on materials provided by Norwegian School of Veterinary Science. Note: Materials may be edited for content and length.


Cite This Page:

Norwegian School of Veterinary Science. "Mapping immune genes in salmon." ScienceDaily. ScienceDaily, 3 October 2011. <www.sciencedaily.com/releases/2011/10/111003151043.htm>.
Norwegian School of Veterinary Science. (2011, October 3). Mapping immune genes in salmon. ScienceDaily. Retrieved October 21, 2014 from www.sciencedaily.com/releases/2011/10/111003151043.htm
Norwegian School of Veterinary Science. "Mapping immune genes in salmon." ScienceDaily. www.sciencedaily.com/releases/2011/10/111003151043.htm (accessed October 21, 2014).

Share This



More Plants & Animals News

Tuesday, October 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

White Lion Cubs Born in Belgrade Zoo

White Lion Cubs Born in Belgrade Zoo

AFP (Oct. 20, 2014) Two white lion cubs, an extremely rare subspecies of the African lion, were recently born at Belgrade Zoo. They are being bottle fed by zoo keepers after they were rejected by their mother after birth. Duration: 00:42 Video provided by AFP
Powered by NewsLook.com
Traditional Farming Methods Gaining Ground in Mali

Traditional Farming Methods Gaining Ground in Mali

AFP (Oct. 20, 2014) He is leading a one man agricultural revolution in Mali - Oumar Diatabe uses traditional farming methods to get the most out of his land and is teaching others across the country how to do the same. Duration: 01:44 Video provided by AFP
Powered by NewsLook.com
Goliath Spider Will Give You Nightmares

Goliath Spider Will Give You Nightmares

Buzz60 (Oct. 20, 2014) An entomologist stumbled upon a South American Goliath Birdeater. With a name like that, you know it's a terrifying creepy crawler. Sean Dowling (@SeanDowlingTV) has the details. Video provided by Buzz60
Powered by NewsLook.com
Adorable Video of Baby Rhino and Lamb Friend Playing

Adorable Video of Baby Rhino and Lamb Friend Playing

Buzz60 (Oct. 20, 2014) Gertjie the Rhino and Lammie the Lamb are teaching the world about animal conservation and friendship. TC Newman (@PurpleTCNewman) has the adorable video! Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins