Featured Research

from universities, journals, and other organizations

New biosensor benefits from melding of carbon nanotubes, DNA

Date:
November 15, 2011
Source:
Purdue University
Summary:
Scientists have developed a method for stacking synthetic DNA and carbon nanotubes onto a biosensor electrode, a development that may lead to more accurate measurements for research related to diabetes and other diseases.

Purdue University scientists have developed a method for stacking synthetic DNA and carbon nanotubes onto a biosensor electrode, a development that may lead to more accurate measurements for research related to diabetes and other diseases.

Standard sensors employ metal electrodes coated with enzymes that react with compounds and produce an electrical signal that can be measured. But the inefficiency of those sensors leads to imperfect measurements.

Carbon nanotubes, cylindrically shaped carbon molecules known to have excellent thermal and electrical properties, have been seen as a possibility for improving sensor performance. The problem is that the materials are not fully compatible with water, which limits their application in biological fluids.

Marshall Porterfield, a professor of agricultural and biological engineering and biomedical engineering, and Jong Hyun Choi, an assistant professor of mechanical engineering, have found a solution. Their findings, reported in the journal The Analyst, describe a sensor that essentially builds itself.

"In the future, we will be able to create a DNA sequence that is complementary to the carbon nanotubes and is compatible with specific biosensor enzymes for the many different compounds we want to measure," Porterfield said. "It will be a self-assembling platform for biosensors at the biomolecular level."

Choi developed a synthetic DNA that will attach to the surface of the carbon nanotubes and make them more water-soluble.

"Once the carbon nanotubes are in a solution, you only have to place the electrode into the solution and charge it. The carbon nanotubes will then coat the surface," Choi said.

The electrode coated with carbon nanotubes will attract the enzymes to finish the sensor's assembly.

The sensor described in the findings was designed for glucose. But Porterfield said it could be easily adapted for various compounds.

"You could mass produce these sensors for diabetes, for example, for insulin management for diabetic patients," Porterfield said.

Porterfield said it may one day be possible to develop other sensors using this technology that could lead to more personalized medicines that could test in real time the effectiveness of drugs on their targets as with cancer patients.

Porterfield said he would continue to develop biosensors to detect different compounds.

The National Institutes of Health and the Office of Naval Research funded the research.


Story Source:

The above story is based on materials provided by Purdue University. The original article was written by Brian Wallheimer. Note: Materials may be edited for content and length.


Journal Reference:

  1. Jin Shi, Tae-Gon Cha, Jonathan C. Claussen, Alfred R. Diggs, Jong Hyun Choi, D. Marshall Porterfield. Microbiosensors based on DNA modified single-walled carbon nanotube and Pt black nanocomposites. The Analyst, 2011; 136 (23): 4916 DOI: 10.1039/c1an15179g

Cite This Page:

Purdue University. "New biosensor benefits from melding of carbon nanotubes, DNA." ScienceDaily. ScienceDaily, 15 November 2011. <www.sciencedaily.com/releases/2011/11/111115133038.htm>.
Purdue University. (2011, November 15). New biosensor benefits from melding of carbon nanotubes, DNA. ScienceDaily. Retrieved September 16, 2014 from www.sciencedaily.com/releases/2011/11/111115133038.htm
Purdue University. "New biosensor benefits from melding of carbon nanotubes, DNA." ScienceDaily. www.sciencedaily.com/releases/2011/11/111115133038.htm (accessed September 16, 2014).

Share This



More Matter & Energy News

Tuesday, September 16, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Manufacturer Prints 3-D Car In Record Time

Manufacturer Prints 3-D Car In Record Time

Newsy (Sep. 15, 2014) — Automobile manufacturer Local Motors created a drivable electric car using a 3-D printer. Printing the body only took 44 hours. Video provided by Newsy
Powered by NewsLook.com
Refurbished New York Subway Tunnel Unveiled After Sandy Damage

Refurbished New York Subway Tunnel Unveiled After Sandy Damage

Reuters - US Online Video (Sep. 15, 2014) — New York officials unveil subway tunnels that were refurbished after Superstorm Sandy. Nathan Frandino reports. Video provided by Reuters
Powered by NewsLook.com
Frustration As Drone Industry Outpaces Regulation In U.S.

Frustration As Drone Industry Outpaces Regulation In U.S.

Newsy (Sep. 14, 2014) — U.S. firms worry they’re falling behind in the marketplace as the FAA considers how to regulate commercial drones. Video provided by Newsy
Powered by NewsLook.com
Smart Gun Innovators Fear Backlash From Gun Rights Advocates

Smart Gun Innovators Fear Backlash From Gun Rights Advocates

Newsy (Sep. 14, 2014) — Winners of a contest for smart gun design are asking not to be named after others in the industry received threats for marketing similar products. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins