Featured Research

from universities, journals, and other organizations

The fat-burning zone: News on burning fat

Date:
November 17, 2011
Source:
University of Oslo
Summary:
Obesity-related diseases are an increasing health problem. Researchers have now uncovered a central component of fat metabolism.

Obesity-related diseases are an increasing health problem. Researchers at the University of Oslo have now uncovered a central component of fat metabolism.

Related Articles


It is well known that exercise results in "fat burning." Physical activity and fight-or-flight responses increase the levels of hormones like adrenaline, inducing the metabolism of fat. Until recently, some of the molecular details of exactly how this works have been a mystery.

Fats are stored inside fat cells within specialized compartments known as "lipid droplets" (LD), and their metabolism requires the cooperative action of several different proteins. Not only must these proteins act together, they must also be found within close physical proximity on the surface of the lipid droplets. This clustering of proteins is achieved by what are called anchoring proteins.

The essential role of the anchoring protein OPA1 in lipid metabolism was recently demonstrated by researchers in the Taskén group, and the study published in the EMBO Journal. Dr. Greenberg and colleagues from Harvard and Stanford University underlined on the importance of these findings in a research highlight: "The observation of [OPA1] on the LD surface provides an important step in understanding the regulation of LD biology.."

"It has taken a long time to sort this out." said Group Leader, Professor Kjetil Taskén. "In fact, the publication of this paper summarizes the work of two postdoctoral researchers and two PhD students over a period of more than seven years."


Story Source:

The above story is based on materials provided by University of Oslo. Note: Materials may be edited for content and length.


Journal References:

  1. Guillaume Pidoux, Oliwia Witczak, Elisabeth Jarnćss, Linda Myrvold, Henning Urlaub, Anne Jorunn Stokka, Thomas Küntziger, Kjetil Taskén. Optic atrophy 1 is an A-kinase anchoring protein on lipid droplets that mediates adrenergic control of lipolysis. The EMBO Journal, 2011; 30 (21): 4371 DOI: 10.1038/emboj.2011.365
  2. Andrew S Greenberg, Fredric B Kraemer, Krishnakant G Soni, Mark P Jedrychowski, Qing-Wu Yan, Christine E Graham, Thomas A Bowman, Ayla Mansur. Lipid droplet meets a mitochondrial protein to regulate adipocyte lipolysis. The EMBO Journal, 2011; 30 (21): 4337 DOI: 10.1038/emboj.2011.371

Cite This Page:

University of Oslo. "The fat-burning zone: News on burning fat." ScienceDaily. ScienceDaily, 17 November 2011. <www.sciencedaily.com/releases/2011/11/111116103819.htm>.
University of Oslo. (2011, November 17). The fat-burning zone: News on burning fat. ScienceDaily. Retrieved March 27, 2015 from www.sciencedaily.com/releases/2011/11/111116103819.htm
University of Oslo. "The fat-burning zone: News on burning fat." ScienceDaily. www.sciencedaily.com/releases/2011/11/111116103819.htm (accessed March 27, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, March 27, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

House Ready to Pass Medicare Doc Bill

House Ready to Pass Medicare Doc Bill

AP (Mar. 26, 2015) — In rare bipartisan harmony, congressional leaders pushed a $214 billion bill permanently blocking physician Medicare cuts toward House passage Thursday, moving lawmakers closer to resolving a problem that has plagued them for years. (March 26) Video provided by AP
Powered by NewsLook.com
HIV Outbreak Prompts Public Health Emergency In Indiana

HIV Outbreak Prompts Public Health Emergency In Indiana

Newsy (Mar. 26, 2015) — Indiana Gov. Mike Pence says he will bring additional state resources to help stop the epidemic. Video provided by Newsy
Powered by NewsLook.com
Indiana Permits Needle Exchange as HIV Cases Skyrocket

Indiana Permits Needle Exchange as HIV Cases Skyrocket

Reuters - US Online Video (Mar. 26, 2015) — Governor Mike Pence declares the recent HIV outbreak in rural Indiana a "public health emergency" and authorizes a short-term needle-exchange program. Rough Cut (no reporter narration) Video provided by Reuters
Powered by NewsLook.com
AAA: Distracted Driving a Serious Teen Problem

AAA: Distracted Driving a Serious Teen Problem

AP (Mar. 25, 2015) — While distracted driving is not a new problem for teens, new research from the AAA Foundation for Traffic Safety says it&apos;s much more serious than previously thought. (March 25) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins