Featured Research

from universities, journals, and other organizations

New device creates lipid spheres that mimic cell membranes

Date:
January 18, 2012
Source:
American Institute of Physics
Summary:
A new way of manipulating fluids on microscopic levels brings us one step closer to "bottom-up" artificial cell constructs.

Opening up a new door in synthetic biology, a team of researchers has developed a microfluidic device that produces a continuous supply of tiny lipid spheres that are similar in many ways to a cell's outer membrane. "Cells are essentially small, complex bioreactors enclosed by phospholipid membranes," said Abraham Lee from the University of California, Irvine.

Related Articles


"Effectively producing vesicles with lipid membranes that mimic those of natural cells is a valuable tool for fundamental biology research, and it's also an important first step in the hoped-for production of an artificial cell." The researchers have taken an important step in advancing this field by developing a single system that quickly and efficiently performs all the necessary steps to create stable lipid vesicles. Current multistep production methods create vesicles that have inconsistent sizes and layers and short usable lifespans, and they are often contaminated with solvents used in their production.

A paper accepted for publication in the AIP's journal Biomicrofluidics reports that the new microfluidic design overcomes these previous hurdles by generating and manipulating precisely sized droplets of water in an oil environment. This produces an oil-and-water membrane that serves as a scaffold around which lipids molecules assemble. As the membrane dissolves over time, the accumulated lipids form a stable, uniform vesicle that shares many of a natural cell membrane's chemical and physical attributes.

Article: "Stable, Biocompatible Lipid Vesicle Generation by Solvent Extraction-based Droplet Microfluidics" is accepted for publication in the journal Biomicrofluidics.

Authors: Shai-Yen The, Ruba Khnouf, Hugh Fan, Abraham Lee


Story Source:

The above story is based on materials provided by American Institute of Physics. Note: Materials may be edited for content and length.


Cite This Page:

American Institute of Physics. "New device creates lipid spheres that mimic cell membranes." ScienceDaily. ScienceDaily, 18 January 2012. <www.sciencedaily.com/releases/2011/12/111216112856.htm>.
American Institute of Physics. (2012, January 18). New device creates lipid spheres that mimic cell membranes. ScienceDaily. Retrieved March 27, 2015 from www.sciencedaily.com/releases/2011/12/111216112856.htm
American Institute of Physics. "New device creates lipid spheres that mimic cell membranes." ScienceDaily. www.sciencedaily.com/releases/2011/12/111216112856.htm (accessed March 27, 2015).

Share This


More From ScienceDaily



More Plants & Animals News

Friday, March 27, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Jockey Motion Tracking Reveals Racing Prowess

Jockey Motion Tracking Reveals Racing Prowess

Reuters - Innovations Video Online (Mar. 26, 2015) Using motion tracking technology, researchers from the Royal Veterinary College (RVC) are trying to establish an optimum horse riding style to train junior jockeys, as well as enhance safety, health and well-being of both racehorses and jockeys. Matthew Stock reports. Video provided by Reuters
Powered by NewsLook.com
Botswana Talks to End Illegal Wildlife Trade

Botswana Talks to End Illegal Wildlife Trade

AFP (Mar. 25, 2015) Experts are gathering in Botswana to try to end the illegal wildlife trade that is decimating populations of elephants, rhinos and other threatened species. Duration: 01:05 Video provided by AFP
Powered by NewsLook.com
Elephants Help Keep 18-Wheeler From Toppling Over

Elephants Help Keep 18-Wheeler From Toppling Over

Newsy (Mar. 25, 2015) The Natchitoches Parish Sheriff&apos;s Office discovered two elephants keeping a tractor-trailer that had gotten stuck in some mud upright on a highway. Video provided by Newsy
Powered by NewsLook.com
Baby 'pet' Orangutan Rescued from Chicken Cage Takes First Steps

Baby 'pet' Orangutan Rescued from Chicken Cage Takes First Steps

Reuters - Light News Video Online (Mar. 25, 2015) Buti, a baby orangutan who was left malnourished in a chicken cage before his rescue, takes his first steps after months of painful physical therapy. Mana Rabiee reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins