Featured Research

from universities, journals, and other organizations

Researchers demonstrate new DNA detection technique

Date:
December 19, 2011
Source:
University of Notre Dame
Summary:
Researchers have demonstrated a novel DNA detection method that could prove suitable for many real-world applications.

A team of researchers from the University of Notre Dame have demonstrated a novel DNA detection method that could prove suitable for many real-world applications.

Physicists Carol Tanner and Steven Ruggiero led the team in the application of a new technique called laser transmission spectroscopy (LTS). LTS is capable of rapidly determining the size, shape and number of nanoparticles in suspension.

In a new paper appearing in the international, peer-reviewed, open-access, online publication PLoS ONE, the team describes how they applied LTS as a novel method for detecting species-specific DNA where the presence of one invasive species, the quagga mussel, was differentiated from a closely related invasive sister species, the zebra mussel.

The research was carried out in support of and cooperation with Notre Dame's Environmental Change Initiative (ECI). Scientists from ECI are using environmental DNA (eDNA) as part of their surveillance of Asian carp in the Great Lakes region.

The results of the research demonstrate the basic premise of DNA detection by LTS in the laboratory.

The Notre Dame research team points out that the LTS technique has many benefits over established DNA detection techniques. The technique is highly sensitive and takes only a few seconds to genetically score a sample for species presence or absence. The researchers also feel that LTS technology will prove much more rapid, practical and cost effective than current detection methodologies and could ultimately reach the sensitivity required to eliminate the need for polymerase chain reaction (PCR) amplification.

Although the current paper describes the use of LTS in invasive species detection, the Notre Dame researchers believe that the technique could serve as an important tool in detecting human pathogens and understanding and indicating the presence of genetic diseases such as cancer.

The Notre Dame group is investigating the real-world applications of LTS technology generally and working on transitioning its success from the lab to the field.


Story Source:

The above story is based on materials provided by University of Notre Dame. The original article was written by William G. Gilroy. Note: Materials may be edited for content and length.


Journal Reference:

  1. Frank Li, Andrew R. Mahon, Matthew A. Barnes, Jeffery Feder, David M. Lodge, Ching-Ting Hwang, Robert Schafer, Steven T. Ruggiero, Carol E. Tanner. Quantitative and Rapid DNA Detection by Laser Transmission Spectroscopy. PLoS ONE, 2011; 6 (12): e29224 DOI: 10.1371/journal.pone.0029224

Cite This Page:

University of Notre Dame. "Researchers demonstrate new DNA detection technique." ScienceDaily. ScienceDaily, 19 December 2011. <www.sciencedaily.com/releases/2011/12/111216175240.htm>.
University of Notre Dame. (2011, December 19). Researchers demonstrate new DNA detection technique. ScienceDaily. Retrieved September 2, 2014 from www.sciencedaily.com/releases/2011/12/111216175240.htm
University of Notre Dame. "Researchers demonstrate new DNA detection technique." ScienceDaily. www.sciencedaily.com/releases/2011/12/111216175240.htm (accessed September 2, 2014).

Share This




More Health & Medicine News

Tuesday, September 2, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Get on Your Bike! London Cycling Popularity Soars Despite Danger

Get on Your Bike! London Cycling Popularity Soars Despite Danger

AFP (Sep. 1, 2014) Wedged between buses, lorries and cars, cycling in London isn't for the faint hearted. Nevertheless the number of people choosing to bike in the British capital has doubled over the past 15 years. Duration: 02:27 Video provided by AFP
Powered by NewsLook.com
Can You Train Your Brain To Eat Healthy?

Can You Train Your Brain To Eat Healthy?

Newsy (Sep. 1, 2014) New research says if you condition yourself to eat healthy foods, eventually you'll crave them instead of junk food. Video provided by Newsy
Powered by NewsLook.com
We've Got Mites Living In Our Faces And So Do You

We've Got Mites Living In Our Faces And So Do You

Newsy (Aug. 30, 2014) A new study suggests 100 percent of adult humans (those over 18 years of age) have Demodex mites living in their faces. Video provided by Newsy
Powered by NewsLook.com
Liberia Continues Fight Against Ebola

Liberia Continues Fight Against Ebola

AFP (Aug. 30, 2014) Authorities in Liberia try to stem the spread of the Ebola epidemic by raising awareness and setting up sanitation units for people to wash their hands. Duration: 00:41 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins