Featured Research

from universities, journals, and other organizations

Antiestrogen therapy may decrease risk for melanoma

Date:
January 4, 2012
Source:
American Association for Cancer Research
Summary:
Women with breast cancer who take antiestrogen supplements may be decreasing their risk for melanoma, according to a new study.

Women with breast cancer who take antiestrogen supplements may be decreasing their risk for melanoma, according to a study published in Cancer Prevention Research, a journal of the American Association for Cancer Research.

Related Articles


Christine Bouchardy, M.D., Ph.D., professor at the University of Geneva and head of the Geneva Cancer Registry, and colleagues analyzed data from 7,360 women who had breast cancer between 1980 and 2005. About half (54 percent) of these women received antiestrogen therapy.

The researchers followed the patients until 2008 and recorded 34 melanoma cases during the follow-up period. Risk for melanoma was 60 percent higher among patients who did not receive antiestrogen therapy compared with patients who received antiestrogen therapy.

According to Bouchardy, the increased focus on estrogen's role in breast cancer has led scientists to start questioning what role estrogen is playing in other cancers. "These data reinforce the hypothesis that estrogens play a role in melanoma occurrence," she said.

Bouchardy said this may be due to the fact that estrogens are associated with increased levels of melanocytes and melanin production in human skin, which have been linked to early-stage melanoma. However, she cautioned against widespread antiestrogen supplementation to prevent melanoma in the general population.

"These results need to be replicated in other studies, particularly given the numerous side effects linked to this kind of drug," said Bouchardy.

The study was funded by a grant from the Swiss Research Foundation against Cancer, a nonprofit group.


Story Source:

The above story is based on materials provided by American Association for Cancer Research. Note: Materials may be edited for content and length.


Journal Reference:

  1. C. Huber, C. Bouchardy, R. Schaffar, I. Neyroud-Caspar, G. Vlastos, F.-A. Le Gal, E. Rapiti, S. Benhamou. Antiestrogen Therapy for Breast Cancer Modifies the Risk of Subsequent Cutaneous Melanoma. Cancer Prevention Research, 2011; 5 (1): 82 DOI: 10.1158/1940-6207.CAPR-11-0332

Cite This Page:

American Association for Cancer Research. "Antiestrogen therapy may decrease risk for melanoma." ScienceDaily. ScienceDaily, 4 January 2012. <www.sciencedaily.com/releases/2012/01/120104115124.htm>.
American Association for Cancer Research. (2012, January 4). Antiestrogen therapy may decrease risk for melanoma. ScienceDaily. Retrieved October 26, 2014 from www.sciencedaily.com/releases/2012/01/120104115124.htm
American Association for Cancer Research. "Antiestrogen therapy may decrease risk for melanoma." ScienceDaily. www.sciencedaily.com/releases/2012/01/120104115124.htm (accessed October 26, 2014).

Share This



More Health & Medicine News

Sunday, October 26, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Texas Nurse Nina Pham Cured of Ebola

Texas Nurse Nina Pham Cured of Ebola

AFP (Oct. 25, 2014) — An American nurse who contracted Ebola while caring for a Liberian patient in Texas has been declared free of the virus and will leave the hospital. Duration: 01:01 Video provided by AFP
Powered by NewsLook.com
Toxin-Packed Stem Cells Used To Kill Cancer

Toxin-Packed Stem Cells Used To Kill Cancer

Newsy (Oct. 25, 2014) — A Harvard University Research Team created genetically engineered stem cells that are able to kill cancer cells, while leaving other cells unharmed. Video provided by Newsy
Powered by NewsLook.com
IKEA Desk Converts From Standing to Sitting With One Button

IKEA Desk Converts From Standing to Sitting With One Button

Buzz60 (Oct. 24, 2014) — IKEA is out with a new convertible desk that can convert from a sitting desk to a standing one with just the push of a button. Jen Markham explains. Video provided by Buzz60
Powered by NewsLook.com
Ebola Protective Suits Being Made in China

Ebola Protective Suits Being Made in China

AFP (Oct. 24, 2014) — A factory in China is busy making Ebola protective suits for healthcare workers and others fighting the spread of the virus. Duration: 00:38 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins