Featured Research

from universities, journals, and other organizations

Antiestrogen therapy may decrease risk for melanoma

Date:
January 4, 2012
Source:
American Association for Cancer Research
Summary:
Women with breast cancer who take antiestrogen supplements may be decreasing their risk for melanoma, according to a new study.

Women with breast cancer who take antiestrogen supplements may be decreasing their risk for melanoma, according to a study published in Cancer Prevention Research, a journal of the American Association for Cancer Research.

Related Articles


Christine Bouchardy, M.D., Ph.D., professor at the University of Geneva and head of the Geneva Cancer Registry, and colleagues analyzed data from 7,360 women who had breast cancer between 1980 and 2005. About half (54 percent) of these women received antiestrogen therapy.

The researchers followed the patients until 2008 and recorded 34 melanoma cases during the follow-up period. Risk for melanoma was 60 percent higher among patients who did not receive antiestrogen therapy compared with patients who received antiestrogen therapy.

According to Bouchardy, the increased focus on estrogen's role in breast cancer has led scientists to start questioning what role estrogen is playing in other cancers. "These data reinforce the hypothesis that estrogens play a role in melanoma occurrence," she said.

Bouchardy said this may be due to the fact that estrogens are associated with increased levels of melanocytes and melanin production in human skin, which have been linked to early-stage melanoma. However, she cautioned against widespread antiestrogen supplementation to prevent melanoma in the general population.

"These results need to be replicated in other studies, particularly given the numerous side effects linked to this kind of drug," said Bouchardy.

The study was funded by a grant from the Swiss Research Foundation against Cancer, a nonprofit group.


Story Source:

The above story is based on materials provided by American Association for Cancer Research. Note: Materials may be edited for content and length.


Journal Reference:

  1. C. Huber, C. Bouchardy, R. Schaffar, I. Neyroud-Caspar, G. Vlastos, F.-A. Le Gal, E. Rapiti, S. Benhamou. Antiestrogen Therapy for Breast Cancer Modifies the Risk of Subsequent Cutaneous Melanoma. Cancer Prevention Research, 2011; 5 (1): 82 DOI: 10.1158/1940-6207.CAPR-11-0332

Cite This Page:

American Association for Cancer Research. "Antiestrogen therapy may decrease risk for melanoma." ScienceDaily. ScienceDaily, 4 January 2012. <www.sciencedaily.com/releases/2012/01/120104115124.htm>.
American Association for Cancer Research. (2012, January 4). Antiestrogen therapy may decrease risk for melanoma. ScienceDaily. Retrieved December 19, 2014 from www.sciencedaily.com/releases/2012/01/120104115124.htm
American Association for Cancer Research. "Antiestrogen therapy may decrease risk for melanoma." ScienceDaily. www.sciencedaily.com/releases/2012/01/120104115124.htm (accessed December 19, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, December 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Kids Die While Under Protective Services

Kids Die While Under Protective Services

AP (Dec. 18, 2014) As part of a six-month investigation of child maltreatment deaths, the AP found that hundreds of deaths from horrific abuse and neglect could have been prevented. AP's Haven Daley reports. (Dec. 18) Video provided by AP
Powered by NewsLook.com
Dads-To-Be Also Experience Hormone Changes During Pregnancy

Dads-To-Be Also Experience Hormone Changes During Pregnancy

Newsy (Dec. 18, 2014) A study from University of Michigan researchers found that expectant fathers see a decrease in testosterone as the baby's birth draws near. Video provided by Newsy
Powered by NewsLook.com
Prenatal Exposure To Pollution Might Increase Autism Risk

Prenatal Exposure To Pollution Might Increase Autism Risk

Newsy (Dec. 18, 2014) Harvard researchers found children whose mothers were exposed to high pollution levels in the third trimester were twice as likely to develop autism. Video provided by Newsy
Powered by NewsLook.com
UN: Up to One Million Facing Hunger in Ebola-Hit Countries

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

AFP (Dec. 17, 2014) Border closures, quarantines and crop losses in West African nations battling the Ebola virus could lead to as many as one million people going hungry, UN food agencies said on Wednesday. Duration: 00:52 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins