Featured Research

from universities, journals, and other organizations

Statin use in postmenopausal women associated with increased diabetes risk

Date:
January 20, 2012
Source:
JAMA and Archives Journals
Summary:
The use of statins in postmenopausal women is associated with increased diabetes risk, according to a new study.

The use of statins in postmenopausal women is associated with increased diabetes risk, according to a study published Online First by the Archives of Internal Medicine, one of the JAMA/Archives journals.

Related Articles


But researchers note statins address the cardiovascular consequences of diabetes and current American Diabetes Association guidelines for primary and secondary prevention should not change. Likewise, researchers write that guidelines for statin use in nondiabetic populations also should not change.

Annie L. Culver, B. Pharm, Rochester Methodist Hospital, Mayo Clinic, Rochester, Minn., and colleagues analyzed data from the national, multiyear Women's Health Initiative in the study.

In this study, researchers used WHI data through 2005 and included 153,840 women without diabetes and with a mean (average) age of 63.2 years. Statin use was assessed at enrollment and in year three. At baseline, 7.04 percent of women reported taking statin medication.

The results indicate 10,242 new cases of diabetes and statin use at baseline was associated with an increased risk of diabetes. This association remained after adjusting for other potential variables, including age, race/ethnicity and body mass index, and was observed for all types of statins.

"The results of this study imply that statin use conveys an increased risk of new-onset DM in postmenopausal woman. In keeping with the findings of other studies, our results suggest that statin-induced DM is a medication class effect and not related to potency or to individual statin," the researchers write.

"However, the consequences of statin-induced DM (diabetes mellitus) have not been specifically defined and deserve more attention. Given the wide use of statins in the aging population, further studies among women, men, and diverse ethnicities will clarify DM risk and risk management to optimize therapy," researchers conclude.


Story Source:

The above story is based on materials provided by JAMA and Archives Journals. Note: Materials may be edited for content and length.


Journal Reference:

  1. A. L. Culver, I. S. Ockene, R. Balasubramanian, B. C. Olendzki, D. M. Sepavich, J. Wactawski-Wende, J. E. Manson, Y. Qiao, S. Liu, P. A. Merriam, C. Rahilly-Tierny, F. Thomas, J. S. Berger, J. K. Ockene, J. D. Curb, Y. Ma. Statin Use and Risk of Diabetes Mellitus in Postmenopausal Women in the Women's Health Initiative. Archives of Internal Medicine, 2012; DOI: 10.1001/archinternmed.2011.625

Cite This Page:

JAMA and Archives Journals. "Statin use in postmenopausal women associated with increased diabetes risk." ScienceDaily. ScienceDaily, 20 January 2012. <www.sciencedaily.com/releases/2012/01/120109212017.htm>.
JAMA and Archives Journals. (2012, January 20). Statin use in postmenopausal women associated with increased diabetes risk. ScienceDaily. Retrieved March 29, 2015 from www.sciencedaily.com/releases/2012/01/120109212017.htm
JAMA and Archives Journals. "Statin use in postmenopausal women associated with increased diabetes risk." ScienceDaily. www.sciencedaily.com/releases/2012/01/120109212017.htm (accessed March 29, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, March 29, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

S. Leone in New Anti-Ebola Lockdown

S. Leone in New Anti-Ebola Lockdown

AFP (Mar. 28, 2015) — Sierra Leone imposed a three-day nationwide lockdown Friday for the second time in six months in a bid to prevent a resurgence of the deadly Ebola virus. Duration: 01:17 Video provided by AFP
Powered by NewsLook.com
These Popular Antibiotics Can Cause Permanent Nerve Damage

These Popular Antibiotics Can Cause Permanent Nerve Damage

Newsy (Mar. 27, 2015) — A popular class of antibiotic can leave patients in severe pain and even result in permanent nerve damage. Video provided by Newsy
Powered by NewsLook.com
WH Plan to Fight Antibiotic-Resistant Germs

WH Plan to Fight Antibiotic-Resistant Germs

AP (Mar. 27, 2015) — The White House on Friday announced a five-year plan to fight the threat posed by antibiotic-resistant bacteria amid fears that once-treatable germs could become deadly. (March 27) Video provided by AP
Powered by NewsLook.com
House Ready to Pass Medicare Doc Bill

House Ready to Pass Medicare Doc Bill

AP (Mar. 26, 2015) — In rare bipartisan harmony, congressional leaders pushed a $214 billion bill permanently blocking physician Medicare cuts toward House passage Thursday, moving lawmakers closer to resolving a problem that has plagued them for years. (March 26) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins