Featured Research

from universities, journals, and other organizations

Overweight mothers who smoke while pregnant can damage baby's heart, study finds

Date:
January 30, 2012
Source:
BMJ-British Medical Journal
Summary:
Mothers-to-be who are both overweight and smoke during their pregnancy risk damaging their baby's developing heart, according to new research.

Mothers-to-be who are both overweight and smoke during their pregnancy risk damaging their baby's developing heart, finds research published online in Heart.

Related Articles


Congenital heart abnormalities are some of the most common defects found at birth, with around eight in every 1000 babies affected. A likely cause is only found in 15% of cases.

The authors base their findings on an analysis of almost 800 babies and foetuses who were born with congenital heart abnormalities, but no other defects, between 1997 and 2008.

These babies were compared with 322 children and foetuses who were born with chromosomal abnormalities, but without any heart defects.

The analysis pointed to an enhanced damaging effect for a combination of overweight and smoking as opposed to one of these factors alone, after taking account of influential factors, such as the mother's alcohol consumption and educational attainment.

Mums to be who both smoked and were overweight, with a BMI of 25 or more, were more than 2.5 times as likely to have a child with a congenital heart defect as women who either smoked or were overweight, but not both.

The risk of outflow tract obstructive abnormalities, whereby blood flow from the ventricles of the heart to the pulmonary artery or aorta is reduced/blocked, more than tripled in babies born to overweight mums who smoked while pregnant.

"These results indicate that maternal smoking and overweight may both be involved in the same pathway that causes congenital heart defects," write the authors.

While the exact mode of action is not clear, they point to disturbances in plasma cholesterol, which is independently associated with obesity and smoking, and which results in lower levels of "good" cholesterol and higher levels of "bad" cholesterol.

The findings add to the growing body of evidence for the links between smoking and overweight during pregnancy with, variously, miscarriage/stillbirth, stunted growth, and premature birth, say the authors.


Story Source:

The above story is based on materials provided by BMJ-British Medical Journal. Note: Materials may be edited for content and length.


Journal Reference:

  1. Maria E Baardman, Wilhelmina S Kerstjens-Frederikse, Eva Corpeleijn, Hermien E K de Walle, Robert M W Hofstra, Rolf M F Berger, Marian K Bakker. Combined adverse effects of maternal smoking and high body mass index on heart development in offspring: evidence for interaction? Heart, 2012; DOI: 10.1136/heartjnl-2011-300822

Cite This Page:

BMJ-British Medical Journal. "Overweight mothers who smoke while pregnant can damage baby's heart, study finds." ScienceDaily. ScienceDaily, 30 January 2012. <www.sciencedaily.com/releases/2012/01/120130184532.htm>.
BMJ-British Medical Journal. (2012, January 30). Overweight mothers who smoke while pregnant can damage baby's heart, study finds. ScienceDaily. Retrieved November 27, 2014 from www.sciencedaily.com/releases/2012/01/120130184532.htm
BMJ-British Medical Journal. "Overweight mothers who smoke while pregnant can damage baby's heart, study finds." ScienceDaily. www.sciencedaily.com/releases/2012/01/120130184532.htm (accessed November 27, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, November 27, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Leaves Orphans Alone in Sierra Leone

Ebola Leaves Orphans Alone in Sierra Leone

AFP (Nov. 27, 2014) — The Ebola epidemic sweeping Sierra Leone is having a profound effect on the country's children, many of whom have been left without any family members to support them. Duration: 01:02 Video provided by AFP
Powered by NewsLook.com
Experimental Ebola Vaccine Shows Promise In Human Trial

Experimental Ebola Vaccine Shows Promise In Human Trial

Newsy (Nov. 27, 2014) — A recent test of a prototype Ebola vaccine generated an immune response to the disease in subjects. Video provided by Newsy
Powered by NewsLook.com
Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) — Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
Today's Prostheses Are More Capable Than Ever

Today's Prostheses Are More Capable Than Ever

Newsy (Nov. 26, 2014) — Advances in prosthetics are making replacement body parts stronger and more lifelike than they’ve ever been. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins