Featured Research

from universities, journals, and other organizations

X-ray microscopy seen as next wave in structural biology research

Date:
February 17, 2012
Source:
DOE/Pacific Northwest National Laboratory
Summary:
Researchers will explore how X-ray imaging can surpass X-ray crystallography for gathering detailed structural and functional information.

Snapshots of proteins in repose might someday be replaced by views of proteins caught in action, if researchers presenting at the 2012 annual meeting of the American Association for the Advancement of Science have their way. Researchers will explore how X-ray imaging can surpass X-ray crystallography for gathering detailed structural and functional information, even going as far as CAT-scan-like tomography of cells at the nanometer scale.

X-ray crystallography has served structural biologists well -- researchers who painstakingly purify individual proteins, DNA or other molecules of interest, form them into crystals and bombard them with X-rays to learn what they look like, how they work and how they've evolved over time. But with more than 60,000 unique molecules crystallized, some researchers, such as technologist Louis Terminello, say the relatively easy to crystallize ones are out of the way and biologists need a new tool for structural biology. From the Department of Energy's Pacific Northwest National Laboratory, Terminello has assembled this symposium to explore X-ray imaging as that next powerful tool.

"X-ray imaging allows you to peer through a collection of cells and tissue and keep things as close to their natural state as possible," said Terminello. "Other methods require processes that perturb reality. With the advent of high spatially resolved X-ray technology, we are just on the edge of X-ray microscopy that can show us the architecture inside cells." Terminello hopes the X-ray microscope will transform structural biology the way van Leeuwenhoek's microscope created the field of biology centuries ago.


Story Source:

The above story is based on materials provided by DOE/Pacific Northwest National Laboratory. Note: Materials may be edited for content and length.


Cite This Page:

DOE/Pacific Northwest National Laboratory. "X-ray microscopy seen as next wave in structural biology research." ScienceDaily. ScienceDaily, 17 February 2012. <www.sciencedaily.com/releases/2012/02/120217145916.htm>.
DOE/Pacific Northwest National Laboratory. (2012, February 17). X-ray microscopy seen as next wave in structural biology research. ScienceDaily. Retrieved July 28, 2014 from www.sciencedaily.com/releases/2012/02/120217145916.htm
DOE/Pacific Northwest National Laboratory. "X-ray microscopy seen as next wave in structural biology research." ScienceDaily. www.sciencedaily.com/releases/2012/02/120217145916.htm (accessed July 28, 2014).

Share This




More Plants & Animals News

Monday, July 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Deadly Ebola Virus Threatens West Africa

Deadly Ebola Virus Threatens West Africa

AP (July 28, 2014) West African nations and international health organizations are working to contain the largest Ebola outbreak in history. It's one of the deadliest diseases known to man, but the CDC says it's unlikely to spread in the U.S. (July 28) Video provided by AP
Powered by NewsLook.com
Traditional African Dishes Teach Healthy Eating

Traditional African Dishes Teach Healthy Eating

AP (July 28, 2014) Classes are being offered nationwide to encourage African Americans to learn about cooking fresh foods based on traditional African cuisine. The program is trying to combat obesity, heart disease and other ailments often linked to diet. (July 28) Video provided by AP
Powered by NewsLook.com
Asteroid's Timing Was 'Colossal Bad Luck' For The Dinosaurs

Asteroid's Timing Was 'Colossal Bad Luck' For The Dinosaurs

Newsy (July 28, 2014) The asteroid that killed the dinosaurs struck at the worst time for them. A new study says that if it hit earlier or later, they might've survived. Video provided by Newsy
Powered by NewsLook.com
Raw: Sea Turtle Hatchlings Emerge from Nest

Raw: Sea Turtle Hatchlings Emerge from Nest

AP (July 27, 2014) A live-streaming webcam catches loggerhead sea turtle hatchlings emerging from a nest in the Florida Keys. (July 27) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins