Featured Research

from universities, journals, and other organizations

New model gives hands-on help for learning the secrets of molecules

Date:
August 24, 2012
Source:
American Institute of Physics (AIP)
Summary:
Squishy models are anything but child’s play as they help researchers understand the building-block nature of proteins.

The models will enable researchers to quickly and collaboratively see, touch, and test ideas about molecular interactions and the behavior of proteins.
Credit: Masaru Kawakami/ Review of Scientific Instruments

For biology researchers, the complex world of molecular proteins -- where tens of thousands of atoms can comprise a single protein -- may be getting clearer with the help of a new soft, transparent, and squishy silicone model they can hold in their hands.

Its advantage over traditional computer and solid models is that it is mostly transparent and easy to manipulate, which will help researchers more intuitively understand protein structures, positions, and interactions. The models will enable researchers to quickly and collaboratively see, touch, and test ideas about molecular interactions and the behavior of proteins. These insights are keys to innovation in drug design because they help generate discussion about what a particular molecular surface might be like and how a protein is shaped and structured.

The models also allow researchers to simulate docking maneuvers involving molecules known as ligands and their partners, a chemical binding step that can turn a biological process on or off.

This boost to molecular modeling comes from Masaru Kawakami, Ph.D., a biophysicist researcher at JAIST (Japan Advanced Institute of Science and Technology) in Ishikawa, Japan. It appears in the current issue of the American Institute of Physics (AIP) journal Review of Scientific Instruments.

"Because my new model is soft, users can deform the model and experience ligand binding or protein-protein association, which has never been possible with other physical molecule models," said Kawakami. "I believe my model would be an effective discussion tool for the classroom or laboratory to stimulate inspired learning."


Story Source:

The above story is based on materials provided by American Institute of Physics (AIP). Note: Materials may be edited for content and length.


Journal Reference:

  1. Masaru Kawakami. A soft and transparent handleable protein model. Review of Scientific Instruments, 2012; 83 (8): 084303 DOI: 10.1063/1.4739961

Cite This Page:

American Institute of Physics (AIP). "New model gives hands-on help for learning the secrets of molecules." ScienceDaily. ScienceDaily, 24 August 2012. <www.sciencedaily.com/releases/2012/08/120824081921.htm>.
American Institute of Physics (AIP). (2012, August 24). New model gives hands-on help for learning the secrets of molecules. ScienceDaily. Retrieved September 22, 2014 from www.sciencedaily.com/releases/2012/08/120824081921.htm
American Institute of Physics (AIP). "New model gives hands-on help for learning the secrets of molecules." ScienceDaily. www.sciencedaily.com/releases/2012/08/120824081921.htm (accessed September 22, 2014).

Share This



More Matter & Energy News

Monday, September 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Thousands March in NYC Over Climate Change

Thousands March in NYC Over Climate Change

AP (Sep. 21, 2014) — Accompanied by drumbeats, wearing costumes and carrying signs, thousands of demonstrators filled the streets of Manhattan and other cities around the world on Sunday to urge policy makers to take action on climate change. (Sept. 21) Video provided by AP
Powered by NewsLook.com
What This MIT Sensor Could Mean For The Future Of Robotics

What This MIT Sensor Could Mean For The Future Of Robotics

Newsy (Sep. 20, 2014) — MIT researchers developed a light-based sensor that gives robots 100 times the sensitivity of a human finger, allowing for "unprecedented dexterity." Video provided by Newsy
Powered by NewsLook.com
MIT BioSuit A New Take On Traditional Spacesuits

MIT BioSuit A New Take On Traditional Spacesuits

Newsy (Sep. 19, 2014) — The MIT BioSuit could be an alternative to big, bulky traditional spacesuits, but the concept needs some work. Video provided by Newsy
Powered by NewsLook.com
New Music With Recycled Instruments at Colombia Fest

New Music With Recycled Instruments at Colombia Fest

AFP (Sep. 19, 2014) — Jars, bottles, caps and even a pizza box, recovered from the trash, were the elements used by four musical groups at the "RSFEST2014 Sonorities Recycling Festival", in Colombian city of Cali. Duration: 00:49 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins