Featured Research

from universities, journals, and other organizations

Breathable treatment to help prevent asthma attacks

Date:
August 31, 2012
Source:
University of Southampton
Summary:
Researchers in the UK are presenting details of a treatment that could help asthmatics fight infections that trigger 80 percent of asthma attacks.

Details of a treatment that could help asthmatics fight infections that trigger 80% of asthma attacks, developed by University of Southampton spin-out company Synairgen, will be presented to European respiratory experts on Sunday 2 September.

Related Articles


The study provides the first evidence that boosting asthmatics' immune systems can help reduce the number of asthma attacks due to the common cold and other viral infections for the 5.4 million asthmatics in the UK.

Professor Ratko Djukanovic, a respiratory specialist at the University of Southampton and Southampton General Hospital, led the study and will present findings to the European Respiratory Society's annual congress in Vienna.

He says: "We have demonstrated the potential of a treatment, simply breathed in by the patient, which significantly reduces worsening of asthma symptoms and the patient's need to use their asthma inhaler in response to common cold infection. By presenting an immune system protein molecule, interferon beta, to the patient's lungs we can prime their body to challenge infections more effectively."

Professor Djukanovic directs the National Institute for Health Research (NIHR) Southampton Respiratory Biomedical Research Unit, one of 20 sites involved in the trial and a partnership between the University of Southampton and University Hospital Southampton NHS Foundation Trust, funded by NIHR.

He continues: "Southampton researchers, working alongside asthma patients, made the original discovery that weakened immunity amongst asthmatics was key to viral impacts; now study participants are helping us to confirm that discovery and translate it into treatments for their, and other asthmatic patients', benefit through the work of the unit."

Professor Stephen Holgate CBE, leading international asthma specialist at the University of Southampton and founder of Synairgen, says: "This is a really promising breakthrough for the future treatment of asthma and one of the most exciting developments that I have seen in years. These impressive findings across different endpoints, together with the accumulating body of evidence we have generated for other respiratory viruses such as influenza (Swine and Bird flu) and respiratory syncytial virus (RSV), strongly suggest that inhaled interferon beta has the potential to be used as a powerful broad spectrum antiviral respiratory drug in lung diseases such as COPD and pandemic flu."

Richard Marsden, Chief Executive of Synairgen, adds: "This is a great result for the development of our programme. To put this treatment's potential into context, it is estimated that in the US alone there are some 2 to 4 million difficult to treat (Step 4 and 5) adult asthma sufferers who could benefit from this therapy. We continue to analyse the wealth of data generated by this important trial and to plan the next phase of its development, ideally alongside an industry partner."


Story Source:

The above story is based on materials provided by University of Southampton. Note: Materials may be edited for content and length.


Cite This Page:

University of Southampton. "Breathable treatment to help prevent asthma attacks." ScienceDaily. ScienceDaily, 31 August 2012. <www.sciencedaily.com/releases/2012/08/120831104151.htm>.
University of Southampton. (2012, August 31). Breathable treatment to help prevent asthma attacks. ScienceDaily. Retrieved January 27, 2015 from www.sciencedaily.com/releases/2012/08/120831104151.htm
University of Southampton. "Breathable treatment to help prevent asthma attacks." ScienceDaily. www.sciencedaily.com/releases/2012/08/120831104151.htm (accessed January 27, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Tuesday, January 27, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Mistakes Should Serve a Lesson Says WHO

Ebola Mistakes Should Serve a Lesson Says WHO

AFP (Jan. 25, 2015) The World Health Organization&apos;s chief on Sunday admitted the UN agency had been caught napping on Ebola, saying it should serve a lesson to avoid similar mistakes in future. Duration: 00:55 Video provided by AFP
Powered by NewsLook.com
Disneyland Measles Outbreak Spreads To 5 States

Disneyland Measles Outbreak Spreads To 5 States

Newsy (Jan. 24, 2015) Much of the Disneyland measles outbreak is being blamed on the anti-vaccination movement. The CDC encourages just about everyone get immunized. Video provided by Newsy
Powered by NewsLook.com
Growing Measles Outbreak Worries Calif. Parents

Growing Measles Outbreak Worries Calif. Parents

AP (Jan. 23, 2015) Public health officials are rushing to contain a measles outbreak that has sickened 70 people across 6 states and Mexico. The AP&apos;s Raquel Maria Dillon has more. (Jan. 23) Video provided by AP
Powered by NewsLook.com
Smart Wristband to Shock Away Bad Habits

Smart Wristband to Shock Away Bad Habits

Reuters - Innovations Video Online (Jan. 23, 2015) A Boston start-up is developing a wristband they say will help users break bad habits by jolting them with an electric shock. Ben Gruber reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins