Featured Research

from universities, journals, and other organizations

Better blood transfusions for preterm babies

Date:
November 23, 2012
Source:
University of Adelaide
Summary:
Results of new research are a promising step forward in helping to improve the quality of life-saving blood transfusions for preterm babies, by reducing the likelihood of adverse inflammatory responses to the blood.

Results of new research from the University of Adelaide are a promising step forward in helping to improve the quality of life-saving blood transfusions for preterm babies, by reducing the likelihood of adverse inflammatory responses to the blood.

Related Articles


Blood transfusions are among the most common medical procedures experienced by preterm babies, who are often anemic and suffer blood loss.

Researchers from the University of Adelaide's Robinson Institute studied 28 preterm babies (at 28 weeks' gestation or less) who were given packed red blood cell transfusions. The results of this study are now published in the journal Pediatric Research.

"Blood transfusions are a safe and life-saving medical procedure -- they are an important part of modern-day medical care," says the lead author, Dr Michael Stark from the University of Adelaide's Robinson Institute.

"It has been suggested that blood transfusions themselves may be associated with medical complications that are unrelated to the reason for which the transfusion is given, and we don't really know why that is.

"These associations include bronchopulmonary dysplasia and necrotizing entercolitis, inflammatory conditions that affect the lungs and gut of very preterm babies."

The researchers have found a potential mechanism associated with the inflammatory response in the body.

"Within two to four hours of preterm babies receiving a blood transfusion, we have seen elevated levels of cytokines and chemokines -- signaling cells -- that stimulate inflammatory responses in the body," Dr Stark says.

"We believe that the bioactive components of packed red blood cell transfusions are initiating or amplifying these inflammatory processes in the body.

"We hope that by better understanding how the body responds to the blood, we can make improvements to blood transfusions that will reduce the likelihood of inflammatory responses. In this way, the patient will benefit from a life-saving procedure and also experience less complications as a result of that procedure.

"More research is now needed to determine exactly how this response is triggered, and how we might be able to prevent it," he says.


Story Source:

The above story is based on materials provided by University of Adelaide. Note: Materials may be edited for content and length.


Journal Reference:

  1. Amy K. Keir, Andrew J. McPhee, Chad C. Andersen, Michael J. Stark. Plasma cytokines and markers of endothelial activation increase after packed red blood cell transfusion in the preterm infant. Pediatric Research, 2012; DOI: 10.1038/pr.2012.144

Cite This Page:

University of Adelaide. "Better blood transfusions for preterm babies." ScienceDaily. ScienceDaily, 23 November 2012. <www.sciencedaily.com/releases/2012/11/121123132635.htm>.
University of Adelaide. (2012, November 23). Better blood transfusions for preterm babies. ScienceDaily. Retrieved March 1, 2015 from www.sciencedaily.com/releases/2012/11/121123132635.htm
University of Adelaide. "Better blood transfusions for preterm babies." ScienceDaily. www.sciencedaily.com/releases/2012/11/121123132635.htm (accessed March 1, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, March 1, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Could a $34 Smartphone Device Improve HIV Diagnosis in Africa?

Could a $34 Smartphone Device Improve HIV Diagnosis in Africa?

Reuters - Innovations Video Online (Feb. 27, 2015) A dongle that plugs into a Smartphone mimics a lab-based blood test for HIV and syphilis and can detect the diseases in 15 minutes, say researchers. Tara Cleary reports. Video provided by Reuters
Powered by NewsLook.com
Doctor Says Head Transplants Possible Within Two Years

Doctor Says Head Transplants Possible Within Two Years

Buzz60 (Feb. 27, 2015) An Italian doctor is saying he could stick someone&apos;s head onto someone else&apos;s body. Patrick Jones (@Patrick_E_Jones) reports. Video provided by Buzz60
Powered by NewsLook.com
How Your Dentist Could Help Screen You For Diabetes

How Your Dentist Could Help Screen You For Diabetes

Newsy (Feb. 27, 2015) A new study from researchers at New York University suggests dentists could soon use blood samples taken from patients&apos; mouths to test for diabetes. Video provided by Newsy
Powered by NewsLook.com
The Best Tips to Makeover Your Health

The Best Tips to Makeover Your Health

Buzz60 (Feb. 27, 2015) If you&apos;re looking to boost your health this season, there are a few quick and easy steps to prompt you for success. Krystin Goodwin (@Krystingoodwin) has the best tips to give your health a makeover this spring! Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins