Featured Research

from universities, journals, and other organizations

Frog-in-bucket-of-milk folklore leads to potential new antibiotics

Date:
December 12, 2012
Source:
American Chemical Society
Summary:
Following up on an ancient Russian way of keeping milk from going sour -- by putting a frog in the bucket of milk -- scientists have identified a wealth of new antibiotic substances in the skin of the Russian Brown frog.

Following up on an ancient Russian way of keeping milk from going sour -- by putting a frog in the bucket of milk -- scientists have identified a wealth of new antibiotic substances in the skin of the Russian Brown frog. The study appears in ACS' Journal of Proteome Research.

A. T. Lebedev and colleagues explain that amphibians secrete antimicrobial substances called peptides through their skin. These compounds make up the majority of their skin secretions and act as a first line of defense against bacteria and other microorganisms that thrive in the wet places frogs, toads, salamanders and other amphibians live. A previous study identified on the skin of the Russian Brown frog 21 substances with antibiotic and other potential medical activity. Lebedev's team set out to find more of these potential medical treasures.

They used a sensitive laboratory technique to expand the list of such substances on the frogs' skin, identifying 76 additional substances of this kind. They describe lab tests in which some of the substances performed as well against Salmonella and Staphylococcus bacteria as some prescription antibiotic medicines. "These peptides could be potentially useful for the prevention of both pathogenic and antibiotic resistant bacterial strains while their action may also explain the traditional experience of rural populations," the scientists concluded.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. T. Yu. Samgina, E. A Vorontsov, V. A. Gorshkov, E. Hakalehto, O. Hanninen, R. A. Zubarev, A. T. Lebedev. Composition and Antimicrobial Activity of the Skin Peptidome of Russian Brown FrogRana temporaria. Journal of Proteome Research, 2012; 121113155850001 DOI: 10.1021/pr300890m

Cite This Page:

American Chemical Society. "Frog-in-bucket-of-milk folklore leads to potential new antibiotics." ScienceDaily. ScienceDaily, 12 December 2012. <www.sciencedaily.com/releases/2012/12/121212130858.htm>.
American Chemical Society. (2012, December 12). Frog-in-bucket-of-milk folklore leads to potential new antibiotics. ScienceDaily. Retrieved July 25, 2014 from www.sciencedaily.com/releases/2012/12/121212130858.htm
American Chemical Society. "Frog-in-bucket-of-milk folklore leads to potential new antibiotics." ScienceDaily. www.sciencedaily.com/releases/2012/12/121212130858.htm (accessed July 25, 2014).

Share This




More Plants & Animals News

Friday, July 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Boy Attacked by Shark in Florida

Boy Attacked by Shark in Florida

Reuters - US Online Video (July 24, 2014) An 8-year-old boy is bitten in the leg by a shark while vacationing at a Florida beach. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Goma Cheese Brings Whiff of New Hope to DRC

Goma Cheese Brings Whiff of New Hope to DRC

Reuters - Business Video Online (July 24, 2014) The eastern region of the Democratic Republic of Congo, mainly known for conflict and instability, is an unlikely place for the production of fine cheese. But a farm in the village of Masisi, in North Kivu is slowly transforming perceptions of the area. Known simply as Goma cheese, the Congolese version of Dutch gouda has gained popularity through out the region. Ciara Sutton reports. Video provided by Reuters
Powered by NewsLook.com
Dogs Appear To Become Jealous Of Owners' Attention

Dogs Appear To Become Jealous Of Owners' Attention

Newsy (July 23, 2014) A U.C. San Diego researcher says jealousy isn't just a human trait, and dogs aren't the best at sharing the attention of humans with other dogs. Video provided by Newsy
Powered by NewsLook.com
Professor Creates Site Revealing Where People's Cats Live

Professor Creates Site Revealing Where People's Cats Live

Newsy (July 23, 2014) ​It's called I Know Where Your Cat Lives, and you can keep hitting the "Random Cat" button to find more real cats all over the world. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

    Health News

      Environment News

        Technology News



          Save/Print:
          Share:

          Free Subscriptions


          Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

          Get Social & Mobile


          Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

          Have Feedback?


          Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
          Mobile: iPhone Android Web
          Follow: Facebook Twitter Google+
          Subscribe: RSS Feeds Email Newsletters
          Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins