Featured Research

from universities, journals, and other organizations

Probiotics prevent diarrhea related to antibiotic use, review shows

Date:
May 30, 2013
Source:
Wiley
Summary:
Probiotic supplements have the potential to prevent diarrhea caused by antibiotics, according to a new Cochrane systematic review. The authors studied Clostridium difficile (C. difficile) infections in patients taking antibiotics and found symptoms of diarrhea were substantially reduced when patients were also treated with probiotics.

Probiotic supplements have the potential to prevent diarrhea caused by antibiotics, according to a new Cochrane systematic review. The authors studied Clostridium difficile (C. difficile) infections in patients taking antibiotics and found symptoms of diarrhea were substantially reduced when patients were also treated with probiotics.

Related Articles


Antibiotics disturb the beneficial bacteria that live in the gut and allow other harmful bacteria like C. difficile to take hold. Although some people infected with C. difficile show no symptoms, others suffer diarrhea or colitis. The so-called "good bacteria" or yeast in probiotic foods and supplements may offer a safe, low-cost way to help prevent C. difficile-associated diarrhea (CDAD). This finding is important because CDAD is expensive to treat.

CDAD cases were reported in 23 trials involving 4,213 adults and children. Probiotics taken in conjunction with antibiotics reduced the number of people who suffered diarrhea by 64%. Only 2% of participants who took probiotics had CDAD compared to nearly 6% of those who took placebo. In 26 trials reporting on adverse events, there were fewer adverse events in the group taking probiotics.

"In the short-term, taking probiotics in conjunction with antibiotics appears to be a safe and effective way of preventing diarrhea associated with Clostridium difficile infection," said lead researcher Bradley Johnston of The Hospital for Sick Children Research Institute in Toronto, Canada. "The introduction of some probiotic regimens as adjuncts to antibiotics could have an immediate impact on patient outcomes, especially in outbreak settings. However, we still need to establish the probiotic strains and doses that provide the best results, and determine the safety of probiotics in immunocompromised patients."

Although taking probiotics in combination with antibiotics helped to prevent CDAD, it did not reduce the number of people who were infected with C. difficile. "We think it's possible that probiotics act to prevent the symptoms of C. difficile infection rather than to prevent the infection itself," said Johnston. "This possibility needs to be investigated further in future trials, which should help us to understand more about how probiotics work."


Story Source:

The above story is based on materials provided by Wiley. Note: Materials may be edited for content and length.


Journal Reference:

  1. Joshua Z Goldenberg, Stephanie SY Ma, Jane D Saxton, Mark R Martzen, Per O Vandvik, Kristian Thorlund, Gordon H Guyatt, Bradley C Johnston. Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children. Cochrane Review, 2013 DOI: 10.1002/14651858.CD006095.pub3

Cite This Page:

Wiley. "Probiotics prevent diarrhea related to antibiotic use, review shows." ScienceDaily. ScienceDaily, 30 May 2013. <www.sciencedaily.com/releases/2013/05/130530192404.htm>.
Wiley. (2013, May 30). Probiotics prevent diarrhea related to antibiotic use, review shows. ScienceDaily. Retrieved November 26, 2014 from www.sciencedaily.com/releases/2013/05/130530192404.htm
Wiley. "Probiotics prevent diarrhea related to antibiotic use, review shows." ScienceDaily. www.sciencedaily.com/releases/2013/05/130530192404.htm (accessed November 26, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Wednesday, November 26, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
Today's Prostheses Are More Capable Than Ever

Today's Prostheses Are More Capable Than Ever

Newsy (Nov. 26, 2014) Advances in prosthetics are making replacement body parts stronger and more lifelike than they’ve ever been. Video provided by Newsy
Powered by NewsLook.com
From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

Newsy (Nov. 25, 2014) The US FDA is announcing new calorie rules on Tuesday that will require everywhere from theaters to vending machines to include calorie counts. Video provided by Newsy
Powered by NewsLook.com
Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Newsy (Nov. 25, 2014) Need another reason to eat yogurt every day? Researchers now say it could reduce a person's risk of developing type 2 diabetes. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins