Featured Research

from universities, journals, and other organizations

Gene mutations caused by a father's lifestyle can be inherited by multiple generations

Date:
July 1, 2013
Source:
Federation of American Societies for Experimental Biology
Summary:
Gene mutations caused by a father's lifestyle can be inherited by his children, even if those mutations occurred before conception. These findings show that mutations in the germ-line are present in all cells of the children, including their germ cells. This means that a father's lifestyle may affect the DNA of multiple generations and not just his immediate offspring.

Gene mutations caused by a father's lifestyle can be inherited by his children, even if those mutations occurred before conception. What's more, these findings show that mutations in the germ-line are present in all cells of the children, including their own germ cells. This means that a father's lifestyle has the potential to affect the DNA of multiple generations and not just his immediate offspring. These findings were published in the July 2013 issue of The FASEB Journal.

Related Articles


"Our study should be regarded as a pilot study," said Roger Godschalk, Ph.D., a researcher involved in the work from the Department of Toxicology and the School for Nutrition, Toxicology and Metabolism at Maastricht University in the Netherlands. "We hope that our findings support the initiation of new, more elaborate studies that investigate the role of daily life exposures on germ-line mutations transmitted to offspring."

To make this discovery, Godschalk and colleagues looked at two groups of families (father, mother and child) from the Norwegian Mother and Child Cohort Study. The first group had a low yearly income, whereas the second group had a relatively high yearly income. The investigators chose income as a criterion because it generally correlates to lifestyle choices of the parents. For instance, fathers in the low income group were more often cigarette smokers than fathers in the high income group. Researchers looked for DNA mutations in the children and found that they were more frequent in the group with low income fathers than in the group of high income fathers. These results suggest that the parents living conditions before conception may directly impact the health of their children.

"We've known for a very long time that preventive care among expectant mothers is critical to the health and well-being of their children," said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal. "Now, we're learning that fathers don't get a free pass. How they take care of themselves -- even before conception -- affects the genetic makeup of their children, for better or worse."


Story Source:

The above story is based on materials provided by Federation of American Societies for Experimental Biology. Note: Materials may be edited for content and length.


Journal Reference:

  1. J. O. Linschooten, N. Verhofstad, K. Gutzkow, A.-K. Olsen, C. Yauk, Y. Oligschlager, G. Brunborg, F. J. van Schooten, R. W. L. Godschalk. Paternal lifestyle as a potential source of germline mutations transmitted to offspring. The FASEB Journal, 2013; DOI: 10.1096/fj.13-227694

Cite This Page:

Federation of American Societies for Experimental Biology. "Gene mutations caused by a father's lifestyle can be inherited by multiple generations." ScienceDaily. ScienceDaily, 1 July 2013. <www.sciencedaily.com/releases/2013/07/130701135550.htm>.
Federation of American Societies for Experimental Biology. (2013, July 1). Gene mutations caused by a father's lifestyle can be inherited by multiple generations. ScienceDaily. Retrieved April 19, 2015 from www.sciencedaily.com/releases/2013/07/130701135550.htm
Federation of American Societies for Experimental Biology. "Gene mutations caused by a father's lifestyle can be inherited by multiple generations." ScienceDaily. www.sciencedaily.com/releases/2013/07/130701135550.htm (accessed April 19, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, April 19, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Teen E-Cigarette Use Triples, Government Debates Regulations

Teen E-Cigarette Use Triples, Government Debates Regulations

Newsy (Apr. 19, 2015) The Centers for Disease Control and Prevention says in 2014, 13.4 percent of high school students reported smoking an e-cigarette within 30 days. Video provided by Newsy
Powered by NewsLook.com
India's Bidi Workers Suffer for 1,000-a-Day Habit

India's Bidi Workers Suffer for 1,000-a-Day Habit

AFP (Apr. 19, 2015) Popular because of their cheap price, bidis are the main source of income for millions of women and children who manufacture these Indian traditional cigarettes for roughly a dollar a day in dire conditions. Duration: 02:26 Video provided by AFP
Powered by NewsLook.com
Elmo Teams Up With Surgeon General To Promote Vaccinations

Elmo Teams Up With Surgeon General To Promote Vaccinations

Newsy (Apr. 18, 2015) Surgeon General Vivek Murthy released a video with Elmo to promote vaccinations. The video was released the same day the measles outbreak ended. Video provided by Newsy
Powered by NewsLook.com
Our Love Of Puppy Dog Eyes Explained By Science

Our Love Of Puppy Dog Eyes Explained By Science

Newsy (Apr. 17, 2015) Researchers found a spike in oxytocin occurs in both humans and dogs when they gaze into each other&apos;s eyes. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins