Featured Research

from universities, journals, and other organizations

Understanding the mechanics of cells to provide new medical insights

Date:
September 4, 2013
Source:
University of Southampton
Summary:
Mechanobiology is an emerging field of science combining biology and engineering, which investigates the influence of mechanical forces on cellular and molecular processes. Mechanobiology has a large potential to bring new insights into physiological function, aetiology (the study of the causes of diseases) and prevention of chronic diseases including heart failure, cancer, osteoporosis and neuromuscular disorders. It could also contribute to the development of effective regenerative therapies and ultimately, lead to innovations in biomedicine and biotechnology in the coming years.

Computational model of human skin.
Credit: Image courtesy of University of Southampton

University of Southampton researchers are at the forefront of research into mechanobiology, an emerging field of science combining biology and engineering, which investigates the influence of mechanical forces on cellular and molecular processes.

Related Articles


Mechanobiology has a large potential to bring new insights into physiological function, aetiology (the study of the causes of diseases) and prevention of chronic diseases including heart failure, cancer, osteoporosis and neuromuscular disorders. It could also contribute to the development of effective regenerative therapies and ultimately, lead to innovations in biomedicine and biotechnology in the coming years.

Cells reside in mechanically rich and dynamic microenvironments and the complex relationship between mechanics and biology provide cells with the ability to sense and respond to this microenvironment.

Understanding the behaviour of cells from a mechanical viewpoint and the relationship between mechanical deformation and biological response offers an opportunity for halting disease mechanisms, differentiating stem cells and remodelling of engineered and regenerated tissues. Southampton researchers are conducting computational research into cell mechanics and mechanobiology, which is providing new insights not previously available.

Dr Georges Limbert, from the national Centre for Advanced Tribology at Southampton (nCATS), is conducting research that focusses on the modelling of the mechanobiology of biological soft tissues and the physical behaviour of biomaterials. Dr Limbert says: "The multidisciplinary combination of computational simulation and experimental approaches allows exploring phenomena in cell mechanics that are not easily accessible with experimental methods alone. This also offers the potential to accelerate the development of practical solutions in regenerative medicine."

Southampton researchers will present their current work next week to an international audience at the International Workshop on Cell Mechanics and Mechanobiology, taking place on 9 and 10 September in Cape Town, South Africa. This two-day workshop, organised by researchers from the universities of Southampton and Cape Town, will offer lectures from international experts from academia and industry on experimental and computational research in cell mechanics and mechanobiology and its application to chronic diseases.

The event is funded from the Global Partnership Fund programme of the UK Department of Business, Innovation and Skills that aims to promote UK international collaborations in research and innovation. Part of the workshop involves consortium meetings to develop research and innovation proposals and includes a meeting with the UK Minister of State for Universities and Science, Rt Hon David Willets MP.


Story Source:

The above story is based on materials provided by University of Southampton. Note: Materials may be edited for content and length.


Cite This Page:

University of Southampton. "Understanding the mechanics of cells to provide new medical insights." ScienceDaily. ScienceDaily, 4 September 2013. <www.sciencedaily.com/releases/2013/09/130904093530.htm>.
University of Southampton. (2013, September 4). Understanding the mechanics of cells to provide new medical insights. ScienceDaily. Retrieved November 27, 2014 from www.sciencedaily.com/releases/2013/09/130904093530.htm
University of Southampton. "Understanding the mechanics of cells to provide new medical insights." ScienceDaily. www.sciencedaily.com/releases/2013/09/130904093530.htm (accessed November 27, 2014).

Share This


More From ScienceDaily



More Plants & Animals News

Thursday, November 27, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

New Dinosaur Species Found in Museum Collection

New Dinosaur Species Found in Museum Collection

Reuters - Innovations Video Online (Nov. 27, 2014) A British palaeontologist has discovered a new species of dinosaur while studying fossils in a Canadian museum. Pentaceratops aquilonius was related to Triceratops and lived at the end of the Cretaceous Period, around 75 million years ago. Jim Drury has more. Video provided by Reuters
Powered by NewsLook.com
Classic Hollywood Memorabilia Goes Under the Hammer

Classic Hollywood Memorabilia Goes Under the Hammer

Reuters - Entertainment Video Online (Nov. 26, 2014) The iconic piano from "Casablanca" and the Cowardly Lion suit from "The Wizard of Oz" fetch millions at auction. Sara Hemrajani reports. Video provided by Reuters
Powered by NewsLook.com
Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

Newsy (Nov. 25, 2014) The US FDA is announcing new calorie rules on Tuesday that will require everywhere from theaters to vending machines to include calorie counts. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins