Featured Research

from universities, journals, and other organizations

Antimicrobial therapies linked to neonatal infection outbreaks

Date:
October 1, 2013
Source:
Elsevier
Summary:
Administration of antibiotics may have caused successive outbreaks of vancomycin-resistant enterococci (VRE) in a Greek neonatal intensive care unit (NICU), according to a study.

Administration of antibiotics may have caused successive outbreaks of vancomycin-resistant enterococci (VRE) in a Greek neonatal intensive care unit (NICU), according to a study in the October issue of the American Journal of Infection Control, the official publication of the Association for Professionals in Infection Control and Epidemiology (APIC).

Related Articles


A team of physicians at the Aristotle University School of Medicine in Greece responded to two occurrences of VRE in their 44-bed NICU with a bundled intervention of active surveillance, enhanced infection control measures, optimization of antimicrobial usage, and investigation of potential risk factors for VRE colonization over a six-month period. Out of 253 newborns screened, 39.9 percent were found to be carriers of VRE. During the first wave of this outbreak a single clone predominated.

Antimicrobial usage, particularly administration of vancomycin and other glycopeptide antibiotics, was reduced significantly until the outbreak appeared to be over. Just as antimicrobial usage returned to previous levels, a new case of VRE was discovered and a second wave of the outbreak began.

Analysis of the data revealed antimicrobial treatment for late-onset neonatal sepsis and hospitalization during the outbreak as significant risk factors for VRE.

The authors conclude, "Both a high prevalence of VRE colonization and antimicrobial use promoted the transmission of VRE during this biphasic outbreak. Adherence to infection control measures and antimicrobial stewardship policies are of utmost importance."

Enterococci can cause serious healthcare-associated infections in adults, children, and neonates. Vancomycin-resistant enterococci are resistant to vancomycin, the drug often used to treat serious infections for which other medicines may not work. Each year an estimated 20,000 hospitalized U.S. patients become infected with VRE, leading to approximately 1,300 deaths, according to a recent report (www.cdc.gov/drugresistance/threat-report-2013) on antibiotic resistance issued by the Centers for Disease Control and Prevention (CDC).

According to the CDC, the most important action needed to slow the spread of antibiotic-resistant infections is to improve the use of antibiotics. The CDC warns that using antibiotics when they are not needed can lead to the development of antibiotic resistance and can increase a patient's risk of developing a resistant infection in the future.


Story Source:

The above story is based on materials provided by Elsevier. Note: Materials may be edited for content and length.


Journal Reference:

  1. Elisa Civardi, Chryssoula Tzialla, Fausto Baldanti, Luisa Strocchio, Paolo Manzoni, Mauro Stronati. Viral outbreaks in neonatal intensive care units: What we do not know. American Journal of Infection Control, 2013; 41 (10): 854 DOI: 10.1016/j.ajic.2013.01.026

Cite This Page:

Elsevier. "Antimicrobial therapies linked to neonatal infection outbreaks." ScienceDaily. ScienceDaily, 1 October 2013. <www.sciencedaily.com/releases/2013/10/131001115510.htm>.
Elsevier. (2013, October 1). Antimicrobial therapies linked to neonatal infection outbreaks. ScienceDaily. Retrieved October 31, 2014 from www.sciencedaily.com/releases/2013/10/131001115510.htm
Elsevier. "Antimicrobial therapies linked to neonatal infection outbreaks." ScienceDaily. www.sciencedaily.com/releases/2013/10/131001115510.htm (accessed October 31, 2014).

Share This



More Health & Medicine News

Friday, October 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Melafind: Spotting Melanoma Without a Biopsy

Melafind: Spotting Melanoma Without a Biopsy

Ivanhoe (Oct. 31, 2014) The MelaFind device is a pain-free way to check suspicious moles for melanoma, without the need for a biopsy. Video provided by Ivanhoe
Powered by NewsLook.com
Battling Multiple Myeloma

Battling Multiple Myeloma

Ivanhoe (Oct. 31, 2014) The answer isn’t always found in new drugs – repurposing an ‘old’ drug that could mean better multiple myeloma treatment, and hope. Video provided by Ivanhoe
Powered by NewsLook.com
Chronic Inflammation and Prostate Cancer

Chronic Inflammation and Prostate Cancer

Ivanhoe (Oct. 31, 2014) New information that is linking chronic inflammation in the prostate and prostate cancer, which may help doctors and patients prevent cancer in the future. Video provided by Ivanhoe
Powered by NewsLook.com
Sickle Cell: Stopping Kids’ Silent Strokes

Sickle Cell: Stopping Kids’ Silent Strokes

Ivanhoe (Oct. 31, 2014) Blood transfusions are proving crucial to young sickle cell patients by helping prevent strokes, even when there is no outward sign of brain injury. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins