Featured Research

from universities, journals, and other organizations

Radiofrequency ablation effectively treats Barrett's esophagus

Date:
October 2, 2013
Source:
American Gastroenterological Association
Summary:
Radiofrequency ablation leads to remission for 91 percent of patients with dysplastic Barrett's esophagus, according to new figures.

Radiofrequency ablation (RFA) leads to remission for 91 percent of patients with dysplastic Barrett's esophagus, according to new figures published in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association. Dysplastic Barrett's esophagus is the most serious grade of the condition in which precancerous cells are detected in the esophagus.

Related Articles


"In order to make appropriate informed decisions about the use of radiofrequency ablation, patients and providers need to be well versed in the risks and benefits of the procedure," said Nicholas J. Shaheen, MD, MPH, AGAF, study author from the Center for Esophageal Diseases and Swallowing at the University of North Carolina School of Medicine. "This study fills an important gap in research by combining the results of several smaller studies. We now have dependable figures showing that radiofrequency ablation is a safe and effective treatment for most patients with dysplastic Barrett's esophagus."

Investigators conducted a systematic review and meta-analysis of studies published in PubMed and EMBASE to determine trends among Barrett's esophagus patients with intestinal metaplasia (the first phase of the condition in which intestine-like cells develop in the esophagus) and dysplastic Barrett's esophagus. In addition to the high percentage of patients who achieved complete eradication of dysplasia, the investigators reported that complete eradication of intestinal metaplasia was achieved in 78 percent of patients.

The study also found that 13 percent of patients had recurrent intestinal metaplasia after successful eradication. While not substantial, this data should serve as a warning that physicians must keep patients in a surveillance program after completion of therapy. Adverse events (most commonly narrowing of the esophagus, pain and bleeding) were reported in less than 5 percent of patients.

Further analysis and follow up of the U.S. RFA Registry, a nationwide registry of patients treated with radiofrequency ablation for Barrett's esophagus, will be helpful in enhancing generalizability and defining radiofrequency ablation effectiveness in the broader population of patients with Barrett's esophagus.

Radiofrequency ablation is a minimally invasive treatment for Barrett's esophagus in which the inner lining of the esophagus is destroyed by applying high radiofrequency waves to it, causing a thermal injury or "burn." When these abnormal or precancerous cells are destroyed, normal tissue usually regenerates in its place.


Story Source:

The above story is based on materials provided by American Gastroenterological Association. Note: Materials may be edited for content and length.


Journal Reference:

  1. Eric S. Orman, Nan Li, Nicholas J. Shaheen. Efficacy and Durability of Radiofrequency Ablation for Barrett's Esophagus: Systematic Review and Meta-analysis. Clinical Gastroenterology and Hepatology, 2013; 11 (10): 1245 DOI: 10.1016/j.cgh.2013.03.039

Cite This Page:

American Gastroenterological Association. "Radiofrequency ablation effectively treats Barrett's esophagus." ScienceDaily. ScienceDaily, 2 October 2013. <www.sciencedaily.com/releases/2013/10/131002103306.htm>.
American Gastroenterological Association. (2013, October 2). Radiofrequency ablation effectively treats Barrett's esophagus. ScienceDaily. Retrieved March 31, 2015 from www.sciencedaily.com/releases/2013/10/131002103306.htm
American Gastroenterological Association. "Radiofrequency ablation effectively treats Barrett's esophagus." ScienceDaily. www.sciencedaily.com/releases/2013/10/131002103306.htm (accessed March 31, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Tuesday, March 31, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Solitair Device Aims to Takes Guesswork out of Sun Safety

Solitair Device Aims to Takes Guesswork out of Sun Safety

Reuters - Innovations Video Online (Mar. 31, 2015) — The Solitair device aims to take the confusion out of how much sunlight we should expose our skin to. Small enough to be worn as a tie or hair clip, it monitors the user&apos;s sun exposure by taking into account their skin pigment, location and schedule. Matthew Stock reports. Video provided by Reuters
Powered by NewsLook.com
Soda, Salt and Sugar: The Next Generation of Taxes

Soda, Salt and Sugar: The Next Generation of Taxes

Washington Post (Mar. 30, 2015) — Denisa Livingston, a health advocate for the Dinι Community Advocacy Alliance, and the Post&apos;s Abby Phillip discuss efforts around the country to make unhealthy food choices hurt your wallet as much as your waistline. Video provided by Washington Post
Powered by NewsLook.com
UnitedHealth Buys Catamaran

UnitedHealth Buys Catamaran

Reuters - Business Video Online (Mar. 30, 2015) — The $12.8 billion merger will combine the U.S.&apos; third and fourth largest pharmacy benefit managers. Analysts say smaller PBMs could also merge. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com
S. Leone in New Anti-Ebola Lockdown

S. Leone in New Anti-Ebola Lockdown

AFP (Mar. 28, 2015) — Sierra Leone imposed a three-day nationwide lockdown Friday for the second time in six months in a bid to prevent a resurgence of the deadly Ebola virus. Duration: 01:17 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins