Featured Research

from universities, journals, and other organizations

Unnecessary TB deaths to be thing of the past thanks to mobile drug resistance test device

Date:
November 6, 2013
Source:
University of St George's London
Summary:
Thousands of deaths from tuberculosis (or TB), an infectious bacterial disease, could be prevented using a new hand-held device that is being developed to detect potentially fatal drug resistance in less than 15 minutes.

Thousands of deaths from tuberculosis (or TB), an infectious bacterial disease, could be prevented using a new hand-held device that is being developed to detect potentially fatal drug resistance in less than 15 minutes.

Presently of all infectious diseases, only HIV that causes AIDS kills more people than TB. In 2012, an estimated 8.6 million people globally developed TB and 1.3 million died from the disease.

The UK reported 8,751 cases of TB in 2012 with most cases occurring in its cities and London, where mobile TB X-ray units have reappeared, with 3,500 cases being reported last year, more than the Netherlands, Norway, Belgium, and Greece combined, and also more than some African countries, such as The Gambia and Eritrea.

Most cases of TB are curable if treated effectively and promptly and early treatment also prevents the spread of infection.

TB most commonly affects the lungs; although anyone can catch TB if exposed, for most healthy people infection causes no symptoms, but certain people are more vulnerable such as the old or those with weak immune systems.

Currently neither the TB infection itself, nor those people with strains of the disease that are resistant to the most common drugs, can be identified quickly enough for patients to be given a specific prescription without considerable delays.

The World Health Organisation has recently declared the fact that about 3 million people with TB are being missed by health systems across the world as "a public health crisis." The need for better and faster diagnostic tests to help solve this crisis is globally agreed.

But now British biotech firm QuantuMDx has been awarded a 1m government grant towards developing a new rapid test, called Q-TB™, for diagnosis and drug resistance and will build on expertise from specialists at St George's University of London and collaboration with South African laboratories.

The test which uses a small cartridge to hold the sputum sample from patients could be used by doctors, nurses and health professionals in developing countries and in cities where TB is seeing a re-emergence. The test will integrate the DNA analysis device with sputum analysing technology and a TB identification system developed by St George's, University of London and its partners.

Professor Philip Butcher, professor of molecular medical microbiology at St George's, University of London, said: "A simple, fast and accurate method to diagnose TB is urgently needed to effectively fight the disease and prevent its spread."

"It is a major advantage that this new test will also guide the treatment of patients."

Dr Jonathan O'Halloran, QuantuMDx's Chief Scientific Officer and co-founder, said: "The only way we can effectively treat and prevent the spread of MDR-TB is to perform rapid testing at the patients' side, enabling the immediate prescription of targeted drug treatments."

"Our robust handheld device is ideal for use in field settings, and is responsive to the addition of hundreds, even thousands, of new diagnostic targets for disease as these are discovered, thus providing a one-stop testing device meeting the testing needs of communities worldwide."


Story Source:

The above story is based on materials provided by University of St George's London. Note: Materials may be edited for content and length.


Cite This Page:

University of St George's London. "Unnecessary TB deaths to be thing of the past thanks to mobile drug resistance test device." ScienceDaily. ScienceDaily, 6 November 2013. <www.sciencedaily.com/releases/2013/11/131106084404.htm>.
University of St George's London. (2013, November 6). Unnecessary TB deaths to be thing of the past thanks to mobile drug resistance test device. ScienceDaily. Retrieved October 22, 2014 from www.sciencedaily.com/releases/2013/11/131106084404.htm
University of St George's London. "Unnecessary TB deaths to be thing of the past thanks to mobile drug resistance test device." ScienceDaily. www.sciencedaily.com/releases/2013/11/131106084404.htm (accessed October 22, 2014).

Share This



More Health & Medicine News

Wednesday, October 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Orthodontist Mom Jennifer Salzer on the Best Time for Braces

Orthodontist Mom Jennifer Salzer on the Best Time for Braces

Working Mother (Oct. 22, 2014) Is your child ready? Video provided by Working Mother
Powered by NewsLook.com
U.S. Issues Ebola Travel Restrictions, Are Visa Bans Next?

U.S. Issues Ebola Travel Restrictions, Are Visa Bans Next?

Newsy (Oct. 22, 2014) Now that the U.S. is restricting travel from West Africa, some are dropping questions about a travel ban and instead asking about visa bans. Video provided by Newsy
Powered by NewsLook.com
US to Track Everyone Coming from Ebola Nations

US to Track Everyone Coming from Ebola Nations

AP (Oct. 22, 2014) Stepping up their vigilance against Ebola, federal authorities said Wednesday that everyone traveling into the US from Ebola-stricken nations will be monitored for symptoms for 21 days. (Oct. 22) Video provided by AP
Powered by NewsLook.com
Doctors Help Paralysed Man Walk Again, Patient in Disbelief

Doctors Help Paralysed Man Walk Again, Patient in Disbelief

AFP (Oct. 22, 2014) Polish doctors describe how they helped a paralysed man walk again, with the patient in disbelief at the return of sensation to his legs. Duration: 1:04 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins