Featured Research

from universities, journals, and other organizations

Pre-op exam, nerve monitor provides valuable thyroid outcomes information

Date:
November 18, 2013
Source:
Massachusetts Eye and Ear Infirmary
Summary:
Researchers set out to elucidate the electrophysiologic responses LRNs that were preoperatively paralyzed or invaded by malignancy and to use this information for intraoperative management of cancerous RLNs.

Dr. Gregory Randolph (pictured right) has been a longtime advocate of LRN monitoring during thyroid surgery.
Credit: Massachusetts Eye and Ear Infirmary

Intraoperative recurrent laryngeal nerve (RLN) monitoring has gained popularity with approximately 53 percent of general surgeons and 65 percent of otolaryngologists using intraoperative nerve monitoring in select or all cases. The importance of laryngeal exam prior to thyroid surgery has also been increasingly recognized, but the relationship between surgical outcomes and these two parameters has not been studied.

Related Articles


Researchers at Massachusetts Eye and Ear/Harvard Medical School set out to elucidate the electrophysiologic responses LRNs that were preoperatively paralyzed or invaded by malignancy and to use this information for intraoperative management of cancerous RLNs. Their research is described in the November 2013 issue of the journal Otolaryngology -- Head and Neck Surgery.

The study involved retrospective review of all consecutive neck surgeries with nerve monitor performed by senior author Gregory W. Randolph, M.D., director of the division of Thyroid and Parathyroid Surgery at Massachusetts Eye and Ear/Harvard Medical School between December 1995 and January 2007.

Of the 1,138 surgeries performed, 25 patients had preoperative vocal cord dysfunction. In patients with preoperative vocal cord dysfunction, recognizable LRN electrophysiologic activity was preserved in more than 50 percent of the cases. Malignant invasion of the RLN was found in 22 patients. Neural invasion of the RLN was associated with preoperative vocal cord paralysis in only 50 percent of these patients. In nerves invaded by malignancy, 60 percent maintained recognizable electrophysiologic activity, which was more commonly present and robust when vocal cord function was preserved, the authors wrote.

"Knowledge of electrophysiologic intraoperative neural monitoring provides additional functional information and, along with information about the preoperative condition of the vocal cord function, helps to construct decision algorithms regarding intraoperative management of the LRN, predicting postoperative outcomes, and counseling patients on expectations after surgery," said Dr. Randolph, who is also a professor of Otology and Laryngology at Harvard Medical School.


Story Source:

The above story is based on materials provided by Massachusetts Eye and Ear Infirmary. Note: Materials may be edited for content and length.


Journal Reference:

  1. D. Kamani, E. A. Darr, G. W. Randolph. Electrophysiologic Monitoring Characteristics of the Recurrent Laryngeal Nerve Preoperatively Paralyzed or Invaded with Malignancy. Otolaryngology -- Head and Neck Surgery, 2013; 149 (5): 682 DOI: 10.1177/0194599813504735

Cite This Page:

Massachusetts Eye and Ear Infirmary. "Pre-op exam, nerve monitor provides valuable thyroid outcomes information." ScienceDaily. ScienceDaily, 18 November 2013. <www.sciencedaily.com/releases/2013/11/131118112002.htm>.
Massachusetts Eye and Ear Infirmary. (2013, November 18). Pre-op exam, nerve monitor provides valuable thyroid outcomes information. ScienceDaily. Retrieved December 19, 2014 from www.sciencedaily.com/releases/2013/11/131118112002.htm
Massachusetts Eye and Ear Infirmary. "Pre-op exam, nerve monitor provides valuable thyroid outcomes information." ScienceDaily. www.sciencedaily.com/releases/2013/11/131118112002.htm (accessed December 19, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, December 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Best Tips to Curb Holiday Carbs

The Best Tips to Curb Holiday Carbs

Buzz60 (Dec. 19, 2014) It's hard to resist those delicious but fattening carbs we all crave during the winter months, but there are some ways to stay satisfied without consuming the extra calories. Vanessa Freeman (@VanessaFreeTV) has the details. Video provided by Buzz60
Powered by NewsLook.com
Sierra Leone Bikers Spread the Message to Fight Ebola

Sierra Leone Bikers Spread the Message to Fight Ebola

AFP (Dec. 19, 2014) More than 100 motorcyclists hit the road to spread awareness messages about Ebola. Nearly 7,000 people have now died from the virus, almost all of them in west Africa, according to the World Health Organization. Video provided by AFP
Powered by NewsLook.com
Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
Kids Die While Under Protective Services

Kids Die While Under Protective Services

AP (Dec. 18, 2014) As part of a six-month investigation of child maltreatment deaths, the AP found that hundreds of deaths from horrific abuse and neglect could have been prevented. AP's Haven Daley reports. (Dec. 18) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins