Featured Research

from universities, journals, and other organizations

On-field blood test can diagnose sports concussions

Date:
January 9, 2014
Source:
University of Rochester Medical Center
Summary:
A brain protein, S100B, which may soon be detected by a simple finger-stick blood test, accurately distinguishes a sports-related concussion from sports exertion, according to a study.

A brain protein, S100B, which may soon be detected by a simple finger-stick blood test, accurately distinguishes a sports-related concussion from sports exertion, according to a study of college athletes in Rochester, N.Y., and Munich, Germany, and published in PLOS ONE by Jeffrey J. Bazarian, M.D., professor at the University of Rochester.

For years Bazarian and others have been investigating the use of S100B for on-field diagnoses of head injuries. The current method of diagnosing concussion by evaluating symptoms such as loss of consciousness, confusion, and headache are notoriously inaccurate. This makes it difficult for coaches and trainers to decide who should come out of the game.

S100B is a well-accepted biomarker for traumatic brain injury, and Europeans are already using it to decide who is at high risk for intracranial bleeding and in need of head CT scanning.

However, the obstacle to using S100B to diagnose sports concussions has been the observation that brain protein levels tend to rise slightly after physical exertion, for reasons that are not exactly clear. Therefore, scientists must first have the ability to separate the effects of physical exertion from concussion when looking at S100B levels in the blood.

In this study, 46 athletes completed preseason baseline testing for S100B. Researchers re-tested 30 of them after exertion and found that their S100B levels rose on average only about 2% compared to baseline.

Twenty two of the 46 athletes suffered clinically confirmed concussions. And of the 22 athletes, 17 underwent S100B testing within 3 hours of injury. Results showed their S100B levels soared an average of about 81% compared to baseline. Bazarian and his colleagues concluded that in these athletes a rise in S100B levels greater than 45% was nearly diagnostic of concussion.


Story Source:

The above story is based on materials provided by University of Rochester Medical Center. Note: Materials may be edited for content and length.


Journal Reference:

  1. Karin Kiechle, Jeffrey J. Bazarian, Kian Merchant-Borna, Veit Stoecklein, Eric Rozen, Brian Blyth, Jason H. Huang, Samantha Dayawansa, Karl Kanz, Peter Biberthaler. Subject-Specific Increases in Serum S-100B Distinguish Sports-Related Concussion from Sports-Related Exertion. PLoS ONE, 2014; 9 (1): e84977 DOI: 10.1371/journal.pone.0084977

Cite This Page:

University of Rochester Medical Center. "On-field blood test can diagnose sports concussions." ScienceDaily. ScienceDaily, 9 January 2014. <www.sciencedaily.com/releases/2014/01/140109004257.htm>.
University of Rochester Medical Center. (2014, January 9). On-field blood test can diagnose sports concussions. ScienceDaily. Retrieved July 27, 2014 from www.sciencedaily.com/releases/2014/01/140109004257.htm
University of Rochester Medical Center. "On-field blood test can diagnose sports concussions." ScienceDaily. www.sciencedaily.com/releases/2014/01/140109004257.htm (accessed July 27, 2014).

Share This




More Mind & Brain News

Sunday, July 27, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Losing Sleep Leaves You Vulnerable To 'False Memories'

Losing Sleep Leaves You Vulnerable To 'False Memories'

Newsy (July 27, 2014) A new study shows sleep deprivation can make it harder for people to remember specific details of an event. Video provided by Newsy
Powered by NewsLook.com
University Quiz Implies Atheists Are Smarter Than Christians

University Quiz Implies Atheists Are Smarter Than Christians

Newsy (July 25, 2014) An online quiz from a required course at Ohio State is making waves for suggesting atheists are inherently smarter than Christians. Video provided by Newsy
Powered by NewsLook.com
Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

AFP (July 24, 2014) A so-called drugs rehab 'clinic' is closed down in Pakistan after police find scores of ‘patients’ chained up alleging serial abuse. Duration 03:05 Video provided by AFP
Powered by NewsLook.com
New Painkiller Designed To Discourage Abuse: Will It Work?

New Painkiller Designed To Discourage Abuse: Will It Work?

Newsy (July 24, 2014) The FDA approved Targiniq ER on Wednesday, a painkiller designed to keep users from abusing it. Like any new medication, however, it has doubters. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins