Featured Research

from universities, journals, and other organizations

Electronically controlled drugs could minimize side effects

Date:
February 5, 2014
Source:
American Chemical Society
Summary:
Potential side effects of many of today's therapeutic drugs can be downright frightening -- just listen carefully to a drug commercial on TV. These effects often occur when a drug is active throughout the body, not just where and when it is needed. But scientists are reporting progress on a new tailored approach to deliver medicine in a much more targeted way.

Potential side effects of many of today's therapeutic drugs can be downright frightening -- just listen carefully to a drug commercial on TV. These effects often occur when a drug is active throughout the body, not just where and when it is needed. But scientists are reporting progress on a new tailored approach to deliver medicine in a much more targeted way. The study on these new electronically controlled drugs appears in the journal ACS Nano.

Related Articles


Xinyan Tracy Cui and colleagues note that in the lab, "smart" medical implants can now release drugs on demand when exposed to various cues, including ultraviolet light and electrical current. These advances are largely thanks to developments in nanomaterials that can be designed to carry drugs and then release them at specific times and dosages. Researchers have also experimented with loading anti-cancer drugs on thin, tiny sheets of graphene oxide (GO), which have a lot of traits that are useful in drug delivery. But current techniques still require tweaking before they'll be ready for prime time. Cui's team wanted to work out some of the final kinks.

They incorporated GO nanosheets into a polymer thin film that can conduct electricity, loaded it with an anti-inflammatory drug and coated an electrode with it. When they zapped the material with an electric current, they showed that it released the drug consistently in response. They could do this several hundred times. Also, by experimenting with the sizes and thicknesses of the GO sheets, the scientists could change how much drug the nanosheets could carry. Cui said this approach could be useful in treating epilepsy, for example. In that case, medication already lying in wait inside the body could be released at the onset of a seizure.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Cassandra L. Weaver, Jaclyn M. LaRosa, Xiliang Luo, Xinyan Tracy Cui. Electrically Controlled Drug Delivery from Graphene Oxide Nanocomposite Films. ACS Nano, 2014; 140117153145003 DOI: 10.1021/nn406223e

Cite This Page:

American Chemical Society. "Electronically controlled drugs could minimize side effects." ScienceDaily. ScienceDaily, 5 February 2014. <www.sciencedaily.com/releases/2014/02/140205113431.htm>.
American Chemical Society. (2014, February 5). Electronically controlled drugs could minimize side effects. ScienceDaily. Retrieved October 25, 2014 from www.sciencedaily.com/releases/2014/02/140205113431.htm
American Chemical Society. "Electronically controlled drugs could minimize side effects." ScienceDaily. www.sciencedaily.com/releases/2014/02/140205113431.htm (accessed October 25, 2014).

Share This



More Health & Medicine News

Saturday, October 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

IKEA Desk Converts From Standing to Sitting With One Button

IKEA Desk Converts From Standing to Sitting With One Button

Buzz60 (Oct. 24, 2014) IKEA is out with a new convertible desk that can convert from a sitting desk to a standing one with just the push of a button. Jen Markham explains. Video provided by Buzz60
Powered by NewsLook.com
Ebola Protective Suits Being Made in China

Ebola Protective Suits Being Made in China

AFP (Oct. 24, 2014) A factory in China is busy making Ebola protective suits for healthcare workers and others fighting the spread of the virus. Duration: 00:38 Video provided by AFP
Powered by NewsLook.com
WHO: Millions of Ebola Vaccine Doses by 2015

WHO: Millions of Ebola Vaccine Doses by 2015

AP (Oct. 24, 2014) The World Health Organization said on Friday that millions of doses of two experimental Ebola vaccines could be ready for use in 2015 and five more experimental vaccines would start being tested in March. (Oct. 24) Video provided by AP
Powered by NewsLook.com
Doctor in NYC Quarantined With Ebola

Doctor in NYC Quarantined With Ebola

AP (Oct. 24, 2014) An emergency room doctor who recently returned to the city after treating Ebola patients in West Africa has tested positive for the virus. He's quarantined in a hospital. (Oct. 24) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins