Featured Research

from universities, journals, and other organizations

Electronically controlled drugs could minimize side effects

Date:
February 5, 2014
Source:
American Chemical Society
Summary:
Potential side effects of many of today's therapeutic drugs can be downright frightening -- just listen carefully to a drug commercial on TV. These effects often occur when a drug is active throughout the body, not just where and when it is needed. But scientists are reporting progress on a new tailored approach to deliver medicine in a much more targeted way.

Potential side effects of many of today's therapeutic drugs can be downright frightening -- just listen carefully to a drug commercial on TV. These effects often occur when a drug is active throughout the body, not just where and when it is needed. But scientists are reporting progress on a new tailored approach to deliver medicine in a much more targeted way. The study on these new electronically controlled drugs appears in the journal ACS Nano.

Xinyan Tracy Cui and colleagues note that in the lab, "smart" medical implants can now release drugs on demand when exposed to various cues, including ultraviolet light and electrical current. These advances are largely thanks to developments in nanomaterials that can be designed to carry drugs and then release them at specific times and dosages. Researchers have also experimented with loading anti-cancer drugs on thin, tiny sheets of graphene oxide (GO), which have a lot of traits that are useful in drug delivery. But current techniques still require tweaking before they'll be ready for prime time. Cui's team wanted to work out some of the final kinks.

They incorporated GO nanosheets into a polymer thin film that can conduct electricity, loaded it with an anti-inflammatory drug and coated an electrode with it. When they zapped the material with an electric current, they showed that it released the drug consistently in response. They could do this several hundred times. Also, by experimenting with the sizes and thicknesses of the GO sheets, the scientists could change how much drug the nanosheets could carry. Cui said this approach could be useful in treating epilepsy, for example. In that case, medication already lying in wait inside the body could be released at the onset of a seizure.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Cassandra L. Weaver, Jaclyn M. LaRosa, Xiliang Luo, Xinyan Tracy Cui. Electrically Controlled Drug Delivery from Graphene Oxide Nanocomposite Films. ACS Nano, 2014; 140117153145003 DOI: 10.1021/nn406223e

Cite This Page:

American Chemical Society. "Electronically controlled drugs could minimize side effects." ScienceDaily. ScienceDaily, 5 February 2014. <www.sciencedaily.com/releases/2014/02/140205113431.htm>.
American Chemical Society. (2014, February 5). Electronically controlled drugs could minimize side effects. ScienceDaily. Retrieved July 31, 2014 from www.sciencedaily.com/releases/2014/02/140205113431.htm
American Chemical Society. "Electronically controlled drugs could minimize side effects." ScienceDaily. www.sciencedaily.com/releases/2014/02/140205113431.htm (accessed July 31, 2014).

Share This




More Health & Medicine News

Thursday, July 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Health Insurers' Profits Slide

Health Insurers' Profits Slide

Reuters - Business Video Online (July 30, 2014) Obamacare-related costs were said to be behind the profit plunge at Wellpoint and Humana, but Wellpoint sees the new exchanges boosting its earnings for the full year. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com
Concern Grows Over Worsening Ebola Crisis

Concern Grows Over Worsening Ebola Crisis

AFP (July 30, 2014) Pan-African airline ASKY has suspended all flights to and from the capitals of Liberia and Sierra Leone amid the worsening Ebola health crisis, which has so far caused 672 deaths in Guinea, Liberia and Sierra Leone. Duration: 00:43 Video provided by AFP
Powered by NewsLook.com
At Least 20 Chikungunya Cases in New Jersey

At Least 20 Chikungunya Cases in New Jersey

AP (July 30, 2014) At least 20 New Jersey residents have tested positive for chikungunya, a mosquito-borne virus that has spread through the Caribbean. (July 30) Video provided by AP
Powered by NewsLook.com
Xtreme Eating: Your Daily Caloric Intake All On One Plate

Xtreme Eating: Your Daily Caloric Intake All On One Plate

Newsy (July 30, 2014) The Center for Science in the Public Interest released its 2014 list of single meals with whopping calorie counts. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

    Environment News

    Technology News



      Save/Print:
      Share:

      Free Subscriptions


      Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

      Get Social & Mobile


      Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

      Have Feedback?


      Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
      Mobile: iPhone Android Web
      Follow: Facebook Twitter Google+
      Subscribe: RSS Feeds Email Newsletters
      Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins