Featured Research

from universities, journals, and other organizations

Electronically controlled drugs could minimize side effects

Date:
February 5, 2014
Source:
American Chemical Society
Summary:
Potential side effects of many of today's therapeutic drugs can be downright frightening -- just listen carefully to a drug commercial on TV. These effects often occur when a drug is active throughout the body, not just where and when it is needed. But scientists are reporting progress on a new tailored approach to deliver medicine in a much more targeted way.

Potential side effects of many of today's therapeutic drugs can be downright frightening -- just listen carefully to a drug commercial on TV. These effects often occur when a drug is active throughout the body, not just where and when it is needed. But scientists are reporting progress on a new tailored approach to deliver medicine in a much more targeted way. The study on these new electronically controlled drugs appears in the journal ACS Nano.

Related Articles


Xinyan Tracy Cui and colleagues note that in the lab, "smart" medical implants can now release drugs on demand when exposed to various cues, including ultraviolet light and electrical current. These advances are largely thanks to developments in nanomaterials that can be designed to carry drugs and then release them at specific times and dosages. Researchers have also experimented with loading anti-cancer drugs on thin, tiny sheets of graphene oxide (GO), which have a lot of traits that are useful in drug delivery. But current techniques still require tweaking before they'll be ready for prime time. Cui's team wanted to work out some of the final kinks.

They incorporated GO nanosheets into a polymer thin film that can conduct electricity, loaded it with an anti-inflammatory drug and coated an electrode with it. When they zapped the material with an electric current, they showed that it released the drug consistently in response. They could do this several hundred times. Also, by experimenting with the sizes and thicknesses of the GO sheets, the scientists could change how much drug the nanosheets could carry. Cui said this approach could be useful in treating epilepsy, for example. In that case, medication already lying in wait inside the body could be released at the onset of a seizure.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Cassandra L. Weaver, Jaclyn M. LaRosa, Xiliang Luo, Xinyan Tracy Cui. Electrically Controlled Drug Delivery from Graphene Oxide Nanocomposite Films. ACS Nano, 2014; 140117153145003 DOI: 10.1021/nn406223e

Cite This Page:

American Chemical Society. "Electronically controlled drugs could minimize side effects." ScienceDaily. ScienceDaily, 5 February 2014. <www.sciencedaily.com/releases/2014/02/140205113431.htm>.
American Chemical Society. (2014, February 5). Electronically controlled drugs could minimize side effects. ScienceDaily. Retrieved November 23, 2014 from www.sciencedaily.com/releases/2014/02/140205113431.htm
American Chemical Society. "Electronically controlled drugs could minimize side effects." ScienceDaily. www.sciencedaily.com/releases/2014/02/140205113431.htm (accessed November 23, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, November 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

WFP: Ebola Risks Heightened Among Women Throughout Africa

WFP: Ebola Risks Heightened Among Women Throughout Africa

AFP (Nov. 21, 2014) Having children has always been a frightening prospect in Sierra Leone, the world's most dangerous place to give birth, but Ebola has presented an alarming new threat for expectant mothers. Duration: 00:37 Video provided by AFP
Powered by NewsLook.com
Could Your Genes Be The Reason You're Single?

Could Your Genes Be The Reason You're Single?

Newsy (Nov. 21, 2014) Researchers in Beijing discovered a gene called 5-HTA1, and carriers are reportedly 20 percent more likely to be single. Video provided by Newsy
Powered by NewsLook.com
Raw: Paralyzed Marine Walks With Robotic Braces

Raw: Paralyzed Marine Walks With Robotic Braces

AP (Nov. 21, 2014) Marine Corps officials say a special operations officer left paralyzed by a sniper's bullet in Afghanistan walked using robotic leg braces in a ceremony to award him a Bronze Star. (Nov. 21) Video provided by AP
Powered by NewsLook.com
Milestone Birthdays Can Bring Existential Crisis, Study Says

Milestone Birthdays Can Bring Existential Crisis, Study Says

Newsy (Nov. 21, 2014) Researchers find that as people approach new decades in their lives they make bigger life decisions. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins