Featured Research

from universities, journals, and other organizations

Mother to child HIV transmission at record low in the UK

Date:
February 25, 2014
Source:
University College London
Summary:
The rate of mother to child HIV transmission is at an all-time low in the United Kingdom, according to a new paper. The study examined over 12,000 pregnancies in women diagnosed with HIV before or during pregnancy and delivered in 2000-2011; there was a four-fold drop in the rate of mother to child transmissions, from 2.1% in 2000-2001 to 0.46% in 2010-2011. The study also highlighted the extensive inequalities in the availability of interventions to prevent mother to child HIV transmission worldwide.

The rate of mother to child HIV transmission is at an all-time low in the UK, according to a paper published in the journal AIDS.

Related Articles


The study examined over 12,000 pregnancies in women diagnosed with HIV before or during pregnancy and delivered in 2000-2011; there was a four-fold drop in the rate of mother to child transmissions, from 2.1% in 2000-2001 to 0.46% in 2010-2011.

Dr Claire Townsend (UCL Institute of Child Health) said: "Mother to child HIV transmission is now at the lowest level ever in the UK & Ireland, and as far as we're aware such low levels have never been reported on such a large scale."

The continued fall in transmission rates is thought to be due to a combination of factors including earlier initiation of antenatal combination antiretroviral therapy (cART) and an increase in the number of women already on cART when they conceive.

These new statistics are in line with the World Health Organization's goal of virtual elimination of mother to child transmission by 2015. The dramatic fall in the transmission rate in the UK can also be attributed to a very high uptake of antenatal HIV screening, which is offered to all pregnant women, and a multi-disciplinary approach to the management of HIV positive pregnant women and their babies.

The study found that there was a marked decline in the proportion of diagnosed HIV-positive pregnant women who received no antenatal cART from 3.3% in 2000-2006 to 1% in 2007-2011 and an increase in the duration of treatment during pregnancy. A longer duration of treatment was significantly associated with reduced transmission risk.

The study also highlighted the extensive inequalities in the availability of interventions to prevent mother to child HIV transmission worldwide. In the UK 99% of diagnosed HIV positive pregnant women receive cART, whilst UNAIDS estimates that similar treatment regimes in West and Central Africa reach only 27%. The statistics within Europe also show a large gap in access to treatment with transmission rates as much as 4-10 times higher in some parts of Eastern Europe (0.46% transmission in the UK, compared to 2-4% in Russia and 4-5% in the Ukraine), where prevalence of HIV in pregnant women is higher and access to antiretroviral drugs more limited.

Dr Townsend added: "To maintain, and even improve on, these low transmission rates it's vital that we continue to test early for HIV in pregnancy and provide appropriate support to all HIV-positive mothers."


Story Source:

The above story is based on materials provided by University College London. Note: Materials may be edited for content and length.


Journal Reference:

  1. Claire L. Townsend, Laura Byrne, Mario Cortina-Borja, Claire Thorne, Annemiek de Ruiter, Hermione Lyall, Graham P. Taylor, Catherine S. Peckham, Pat A. Tookey. Earlier initiation of ART and further decline in mother-to-child HIV transmission rates, 2000–2011. AIDS, 2014; 1 DOI: 10.1097/QAD.0000000000000212

Cite This Page:

University College London. "Mother to child HIV transmission at record low in the UK." ScienceDaily. ScienceDaily, 25 February 2014. <www.sciencedaily.com/releases/2014/02/140225101646.htm>.
University College London. (2014, February 25). Mother to child HIV transmission at record low in the UK. ScienceDaily. Retrieved March 3, 2015 from www.sciencedaily.com/releases/2014/02/140225101646.htm
University College London. "Mother to child HIV transmission at record low in the UK." ScienceDaily. www.sciencedaily.com/releases/2014/02/140225101646.htm (accessed March 3, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Tuesday, March 3, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Treadmill Test Can Predict Chance Of Death Within A Decade

Treadmill Test Can Predict Chance Of Death Within A Decade

Newsy (Mar. 2, 2015) Johns Hopkins researchers analyzed 58,000 heart stress tests to come up with a formula that predicts a person&apos;s chances of dying in the next decade. Video provided by Newsy
Powered by NewsLook.com
Going Gluten-Free Could Get You A Tax Break

Going Gluten-Free Could Get You A Tax Break

Newsy (Mar. 2, 2015) If a doctor advises you to remove gluten from your diet, you could get a tax deduction on the amount you spend on gluten-free foods. Video provided by Newsy
Powered by NewsLook.com
GlaxoSmithKline and Novartis Try Swapping Success

GlaxoSmithKline and Novartis Try Swapping Success

Reuters - Business Video Online (Mar. 2, 2015) GlaxoSmithKline and Novartis have completed a series of asset swaps worth more than $20 billion. As Grace Pascoe reports they say the deal will reshape both drugmakers. Video provided by Reuters
Powered by NewsLook.com
How Can West Africa Rebuild After Ebola?

How Can West Africa Rebuild After Ebola?

Reuters - Business Video Online (Mar. 2, 2015) How best to rebuild the three West African countries struggling with Ebola will be discussed in Brussels this week. As Hayley Platt reports Sierra Leone has the toughest job ahead - its once thriving economy has been ravaged by the disease. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins