Featured Research

from universities, journals, and other organizations

New standards proposed for gauging muscle decline in older adults

Date:
April 15, 2014
Source:
The Gerontological Society of America
Summary:
Sarcopenia -- the age-related loss of muscle mass and strength -- may put up to 50 percent of seniors at greater risk for disability, yet there is no consensus within the medical community for how this condition should be measured. However, a new collection of articles lays out an empirically derived set of criteria for diagnosing sarcopenia.

Sarcopenia -- the age-related loss of muscle mass and strength -- may put up to 50 percent of seniors at greater risk for disability, yet there is no consensus within the medical community for how this condition should be measured. However, a new collection of articles appearing in The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences (volume 69, number 5) lays out an empirically derived set of criteria for diagnosing sarcopenia.

Related Articles


These recommendations are a result of the Foundation for the National Institutes of Health Biomarkers Consortium Sarcopenia Project, which includes scientists and grantees from the National Institutes of Health, along with other partners in government, academia, and the private sector.

"Low muscle mass and weakness are common and potentially disabling in older adults, but in order to become recognized as a clinical condition, criteria for diagnosis should be based on clinically relevant thresholds and independently validated," state the authors in the lead article of the series.

Their findings suggest that evidence-based cutpoints of grip strength (the force applied by the hand to grip an object) and lean mass could be used in identifying sacropenia. To arrive at the recommended criteria, the scientists working within the Sarcopenia Project pooled data from nine large studies of older people living in the community and analyzed it for grip strength, gait speed, body mass index (BMI), and appendicular lean mass (ALM), which is a measurement of muscle mass in the arms and legs. The total sample included more than 26,000 participants. The average age of the men was about 75.2 years, and the average age of the women was 78.6 years. Women comprised 57 percent of the sample.

Based on their analyses, the investigators recommend that weakness be defined as grip strength less than 57 pounds (26 kilograms) for men and 35 pounds (16 kilograms) or less in women, and low muscle mass defined as an ALM-to-BMI ratio of less than 0.789 for men and 0.512 for women. Both of these criteria were associated with increased risk of developing mobility impairment over three-years of follow-up.

They also noted that the datasets included primarily healthy older people who lived within the community; they noted that additional research is needed in more vulnerable older populations where disability rates are higher.

In the final article in the series, the authors propose adopting the term "skeletal muscle function deficit" as a new terminology to embrace the evolving conceptualization of sarcopenia and other age-related muscle dysfunction; they argue it has the potential to provide a framework for developing diagnostic categories that are useful for both clinical practice and research.

The table of contents for these articles can be found at: http://biomedgerontology.oxfordjournals.org/content/69/5.toc


Story Source:

The above story is based on materials provided by The Gerontological Society of America. Note: Materials may be edited for content and length.


Cite This Page:

The Gerontological Society of America. "New standards proposed for gauging muscle decline in older adults." ScienceDaily. ScienceDaily, 15 April 2014. <www.sciencedaily.com/releases/2014/04/140415181403.htm>.
The Gerontological Society of America. (2014, April 15). New standards proposed for gauging muscle decline in older adults. ScienceDaily. Retrieved November 28, 2014 from www.sciencedaily.com/releases/2014/04/140415181403.htm
The Gerontological Society of America. "New standards proposed for gauging muscle decline in older adults." ScienceDaily. www.sciencedaily.com/releases/2014/04/140415181403.htm (accessed November 28, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, November 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Rural India's Low-Cost Sanitary Pad Revolution

Rural India's Low-Cost Sanitary Pad Revolution

AFP (Nov. 28, 2014) — One man hopes his invention -– a machine that produces cheap sanitary pads –- will help empower Indian women. Duration: 01:51 Video provided by AFP
Powered by NewsLook.com
Research on Bats Could Help Develop Drugs Against Ebola

Research on Bats Could Help Develop Drugs Against Ebola

AFP (Nov. 28, 2014) — In Africa's only biosafety level 4 laboratory, scientists have been carrying out experiments on bats to understand how virus like Ebola are being transmitted, and how some of them resist to it. Duration: 01:18 Video provided by AFP
Powered by NewsLook.com
WHO Says Male Ebola Survivors Should Abstain From Sex

WHO Says Male Ebola Survivors Should Abstain From Sex

Newsy (Nov. 28, 2014) — WHO cites four studies that say Ebola can still be detected in semen up to 82 days after the onset of symptoms. Video provided by Newsy
Powered by NewsLook.com
Ebola Leaves Orphans Alone in Sierra Leone

Ebola Leaves Orphans Alone in Sierra Leone

AFP (Nov. 27, 2014) — The Ebola epidemic sweeping Sierra Leone is having a profound effect on the country's children, many of whom have been left without any family members to support them. Duration: 01:02 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins