Featured Research

from universities, journals, and other organizations

Prenatal risk factors may put children at risk of developing kidney disease

Date:
April 17, 2014
Source:
American Society of Nephrology (ASN)
Summary:
Certain prenatal risk factors are associated with the development of chronic kidney disease in children, according to a study. Future studies should investigate whether modifying these factors could help protect children’s kidney health. Risks for certain types of kidney disease may arise before birth, and researchers suspect that the development of chronic kidney disease (CKD) may be programmed prenatally. These may include birth weight, maternal diabetes, and maternal overweight/obesity.

Certain prenatal risk factors are associated with the development of chronic kidney disease in children, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN). Future studies should investigate whether modifying these factors could help protect children's kidney health.

Related Articles


Risks for certain types of kidney disease may arise before birth, and researchers suspect that the development of chronic kidney disease (CKD) may be programmed prenatally. Christine Hsu, MD (University of Washington) and her colleagues sought to determine the association of childhood CKD with prenatal risk factors, including birth weight, maternal diabetes, and maternal overweight/obesity.

The researchers studied 1994 patients with childhood CKD and 20,032 controls without the disease, and the team linked maternal and infant characteristics in birth records from 1987 to 2008 to hospital discharge data.

The prevalence of CKD was 126.7 cases per 100,000 births. Infants with low birth weight were nearly three times more likely to develop childhood CKD than infants with normal birth weight. Infants were also at increased risk if their mothers developed diabetes during pregnancy of if their mothers were overweight or obese.

"We hope this research leads to further research on ways to reduce kidney disease through either early treatment or prevention that might begin even before birth," said Dr. Hsu. "Previous studies show that strict control of maternal diabetes significantly reduces the risk of congenital malformations in children. We hope our work leads to future studies to investigate whether strict control of maternal diabetes and/or reducing maternal obesity/overweight reduces childhood CKD."


Story Source:

The above story is based on materials provided by American Society of Nephrology (ASN). Note: Materials may be edited for content and length.


Journal Reference:

  1. C. W. Hsu, K. T. Yamamoto, R. K. Henry, A. J. De Roos, J. T. Flynn. Prenatal Risk Factors for Childhood CKD. Journal of the American Society of Nephrology, 2014; DOI: 10.1681/ASN.2013060582

Cite This Page:

American Society of Nephrology (ASN). "Prenatal risk factors may put children at risk of developing kidney disease." ScienceDaily. ScienceDaily, 17 April 2014. <www.sciencedaily.com/releases/2014/04/140417191129.htm>.
American Society of Nephrology (ASN). (2014, April 17). Prenatal risk factors may put children at risk of developing kidney disease. ScienceDaily. Retrieved March 1, 2015 from www.sciencedaily.com/releases/2014/04/140417191129.htm
American Society of Nephrology (ASN). "Prenatal risk factors may put children at risk of developing kidney disease." ScienceDaily. www.sciencedaily.com/releases/2014/04/140417191129.htm (accessed March 1, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, March 1, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Rehab Robot Helps Restore Damaged Muscles and Nerves

Rehab Robot Helps Restore Damaged Muscles and Nerves

Reuters - Innovations Video Online (Mar. 1, 2015) A rehabilitation robot prototype to help restore deteriorated nerves and muscles using electromyography and computer games. Ben Gruber reports. Video provided by Reuters
Powered by NewsLook.com
Could a $34 Smartphone Device Improve HIV Diagnosis in Africa?

Could a $34 Smartphone Device Improve HIV Diagnosis in Africa?

Reuters - Innovations Video Online (Feb. 27, 2015) A dongle that plugs into a Smartphone mimics a lab-based blood test for HIV and syphilis and can detect the diseases in 15 minutes, say researchers. Tara Cleary reports. Video provided by Reuters
Powered by NewsLook.com
Doctor Says Head Transplants Possible Within Two Years

Doctor Says Head Transplants Possible Within Two Years

Buzz60 (Feb. 27, 2015) An Italian doctor is saying he could stick someone&apos;s head onto someone else&apos;s body. Patrick Jones (@Patrick_E_Jones) reports. Video provided by Buzz60
Powered by NewsLook.com
How Your Dentist Could Help Screen You For Diabetes

How Your Dentist Could Help Screen You For Diabetes

Newsy (Feb. 27, 2015) A new study from researchers at New York University suggests dentists could soon use blood samples taken from patients&apos; mouths to test for diabetes. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins