Featured Research

from universities, journals, and other organizations

Statin users consume more calories, fat, and weigh more, than their predecessors

Date:
April 28, 2014
Source:
University of California, Los Angeles (UCLA), Health Sciences
Summary:
People who took statins in the 2009–10 year were consuming more calories and fat than those who used statins 10 years earlier, research shows. There was no similar increase in caloric and fat intake among non–stain users during that decade. Researchers believe this is connected to a false sense of security that could lead to heart disease and other obesity-related illnesses.

People who take statin drugs to lower their cholesterol appear to have developed a false sense of security that could lead to heart disease and other obesity-related illnesses.

A new UCLA-led study suggests that people who took statins in the 2009-10 year were consuming more calories and fat than those who used statins 10 years earlier. There was no similar increase in caloric and fat intake among non-stain users during that decade, researchers said.

In 1999-2000, statin users were consuming fewer calories and less fat than individuals who didn't take these medications, but that is no longer the case. Increases in body mass index -- a measure of obesity that considers body weight and height -- were greater for statin-users than for non-users.

"We believe that this is the first major study to show that people on statins eat more calories and fat than people on those medications did a decade earlier," said the study's primary investigator, Takehiro Sugiyama, who led the research while a visiting scholar in the division of general internal medicine and health services research at the David Geffen School of Medicine at UCLA. "Statins are used by about one-sixth of adults. We may need to reemphasize the importance of dietary modification for those who are taking these medications, now that obesity and diabetes are important problems in society."

The study, subtitled "Gluttony in the Time of Statins?," is published online in the peer-reviewed journal JAMA Internal Medicine. The findings were also presented April 24 at the annual meeting of the Society of General Internal Medicine.

For the study, the researchers used data from the National Health and Nutrition Examination Survey to compare fat and caloric intake among statin users and non-users in 1999-2000 and 2009-10. They found that caloric intake among statin users had risen by 9.6 percent over that decade and that fat consumption had jumped by 14.4 percent. In contrast, caloric and fat intake by non-statin users did not change significantly during the 10-year period.

Statin-users ate roughly 180 kilogram calories less each day and 9 grams of fat less each day than non-users in 1999-2000. But as a result of increases over the decade, the researchers observed no difference in caloric and fat intake between statin users and non-users in 2009-10.

The differences may be explained by the fact that statin users simply don't feel the urgency to reduce their caloric and fat consumption or to lose weight the way statin users 10 years ago did, said Sugiyama, who is now a clinical fellow at the National Center for Global Health and Medicine in Japan. Also, doctors today may be more likely to prescribe statins for patients who eat and weigh more.

Because of the design of this study, the researchers were not able to disentangle the mechanism of the different dietary intake trends. Longitudinal study will be required to answer this question.

"Regardless of the mechanism, there are problems, because eating more fat, especially saturated fat, will lead to higher cholesterol levels, which will undermine the effect of statins and may lead to unnecessary cost of medications," Sugiyama said. "Being overweight also increases the risk of diabetes and hypertension, which also are risk factors for heart disease and stroke.

"Ethical considerations should be included in the discussion. We believe that when physicians prescribe statins, the goal is to decrease patients' cardiovascular risks that cannot be achieved without medications, not to empower them to put butter on steaks."


Story Source:

The above story is based on materials provided by University of California, Los Angeles (UCLA), Health Sciences. The original article was written by Enrique Rivero. Note: Materials may be edited for content and length.


Journal Reference:

  1. Takehiro Sugiyama, Yusuke Tsugawa, Chi-Hong Tseng, Yasuki Kobayashi, Martin F. Shapiro. Different Time Trends of Caloric and Fat Intake Between Statin Users and Nonusers Among US Adults. JAMA Internal Medicine, 2014; DOI: 10.1001/jamainternmed.2014.1927

Cite This Page:

University of California, Los Angeles (UCLA), Health Sciences. "Statin users consume more calories, fat, and weigh more, than their predecessors." ScienceDaily. ScienceDaily, 28 April 2014. <www.sciencedaily.com/releases/2014/04/140428094048.htm>.
University of California, Los Angeles (UCLA), Health Sciences. (2014, April 28). Statin users consume more calories, fat, and weigh more, than their predecessors. ScienceDaily. Retrieved August 30, 2014 from www.sciencedaily.com/releases/2014/04/140428094048.htm
University of California, Los Angeles (UCLA), Health Sciences. "Statin users consume more calories, fat, and weigh more, than their predecessors." ScienceDaily. www.sciencedaily.com/releases/2014/04/140428094048.htm (accessed August 30, 2014).

Share This




More Health & Medicine News

Saturday, August 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

3 Things To Know About The Ebola Outbreak's Progression

3 Things To Know About The Ebola Outbreak's Progression

Newsy (Aug. 29, 2014) Here are three things you need to know about the deadly Ebola outbreak's progression this week. Video provided by Newsy
Powered by NewsLook.com
Killer Amoeba Found in Louisiana Water System

Killer Amoeba Found in Louisiana Water System

AP (Aug. 28, 2014) State health officials say testing has confirmed the presence of a killer amoeba in a water system serving three St. John the Baptist Parish towns. (Aug. 28) Video provided by AP
Powered by NewsLook.com
Who Could Be Burnt by WHO's E-Cigs Move?

Who Could Be Burnt by WHO's E-Cigs Move?

Reuters - Business Video Online (Aug. 28, 2014) The World Health Organisation has called for the regulation of electronic cigarettes as both tobacco and medical products. Ciara Lee looks at the impact of the move on the tobacco industry. Video provided by Reuters
Powered by NewsLook.com
CDC Director On Ebola Outbreak: 'It's Worse Than I Feared'

CDC Director On Ebola Outbreak: 'It's Worse Than I Feared'

Newsy (Aug. 28, 2014) CDC director Tom Frieden says the Ebola outbreak is even worse than he feared. But he also said there's still hope to contain it. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins