Featured Research

from universities, journals, and other organizations

Sleep apnea common after acute respiratory failure

Date:
May 18, 2014
Source:
American Thoracic Society (ATS)
Summary:
Clinically important sleep apnea is common among survivors of acute respiratory failure, according to a new study. “Insomnia is a frequent complaint among survivors of critical illness,” said one researcher. “We examined a small cohort of survivors of acute respiratory failure to understand modifiable contributors to insomnia, including sleep apnea.”

Clinically important sleep apnea is common among survivors of acute respiratory failure, according to a new study presented at the 2014 American Thoracic Society International Conference.

“Insomnia is a frequent complaint among survivors of critical illness,” said Dr. Elizabeth Parsons, MD, MSc, of the Division of Pulmonary & Critical Care Medicine at the University of Washington in Seattle. “We examined a small cohort of survivors of acute respiratory failure to understand modifiable contributors to insomnia, including sleep apnea.”

The study involved 21 patients with acute respiratory failure, defined as an acute need for at least 48 hours of mechanical ventilation. Assessment included the Insomnia Severity Index and in-home level II overnight polysomnography three months after hospital discharge. Sleep-disordered breathing was assessed with the Apnea Hypopnea Index (AHI) and the Respiratory Distress Index (RDI). The AHI measures the average number of apneas (breathing cessations) and hypopneas (partial obstructions) per hour. The Respiratory Distress Index (RDI) measures the average number of respiratory disturbances per hour (apneas, hypopneas, and milder events called respiratory effort–related arousals). An RDI of 15 or greater was considered clinically relevant to sleep quality and daytime function. An AHI of 15 or greater may be a risk factor for cardiovascular morbidity.

Among the 14 patients who underwent polysomnography, the majority met criteria for clinically-relevant sleep apnea, with 13 having an RDI of 15 or greater and 10 having an AHI of 15 or greater. Mean RDI was 38 and mean AHI was 29. Oxygen desaturations were generally mild, with an average 3% oxygen desaturation index of 8 (number of times per hour that oxygen level drops by 3 percent or more). Insomnia severity did not significantly correlate with the presence of sleep-disordered breathing.

“The incidence and severity of sleep apnea we observed among survivors of acute respiratory failure, if replicated in larger studies, are cause for concern,” said Dr. Parsons. “Some patients had clinically significant sleep apnea despite lack of sleep complaints. Evaluating and treating sleep apnea may significantly impact the health and well-being of these patients.”

“It is important to note that trauma was the inciting event for acute respiratory failure in 57% of our tested subjects. By subject report, 29% were actively taking an opiate pain medication at the time of testing. Opiates can worsen sleep apnea by reducing upper airway tone and central respiratory drive. Our results suggest that sleep apnea is common after acute respiratory failure, with central-acting medications serving as one potential contributor.”


Story Source:

The above story is based on materials provided by American Thoracic Society (ATS). Note: Materials may be edited for content and length.


Cite This Page:

American Thoracic Society (ATS). "Sleep apnea common after acute respiratory failure." ScienceDaily. ScienceDaily, 18 May 2014. <www.sciencedaily.com/releases/2014/05/140518164103.htm>.
American Thoracic Society (ATS). (2014, May 18). Sleep apnea common after acute respiratory failure. ScienceDaily. Retrieved July 23, 2014 from www.sciencedaily.com/releases/2014/05/140518164103.htm
American Thoracic Society (ATS). "Sleep apnea common after acute respiratory failure." ScienceDaily. www.sciencedaily.com/releases/2014/05/140518164103.htm (accessed July 23, 2014).

Share This




More Health & Medicine News

Wednesday, July 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Courts Conflicted Over Healthcare Law

Courts Conflicted Over Healthcare Law

AP (July 22, 2014) Two federal appeals courts issued conflicting rulings Tuesday on the legality of the federally-run healthcare exchange that operates in 36 states. (July 22) Video provided by AP
Powered by NewsLook.com
Why Do People Believe We Only Use 10 Percent Of Our Brains?

Why Do People Believe We Only Use 10 Percent Of Our Brains?

Newsy (July 22, 2014) The new sci-fi thriller "Lucy" is making people question whether we really use all our brainpower. But, as scientists have insisted for years, we do. Video provided by Newsy
Powered by NewsLook.com
Scientists Find New Way To Make Human Platelets

Scientists Find New Way To Make Human Platelets

Newsy (July 22, 2014) Boston scientists have discovered a new way to create fully functioning human platelets using a bioreactor and human stem cells. Video provided by Newsy
Powered by NewsLook.com
Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

TheStreet (July 21, 2014) New research shows Gilead Science's drug Sovaldi helps in curing hepatitis C in those who suffer from HIV. In a medical study, the combination of Gilead's Hep C drug with anti-viral drug Ribavirin cured 76% of HIV-positive patients suffering from the most common hepatitis C strain. Hepatitis C and related complications have been a top cause of death in HIV-positive patients. Typical medication used to treat the disease, including interferon proteins, tended to react badly with HIV drugs. However, Sovaldi's %1,000-a-pill price tag could limit the number of patients able to access the treatment. TheStreet's Keris Lahiff reports from New York. Video provided by TheStreet
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins