Featured Research

from universities, journals, and other organizations

Cigarette smoking, male sex: Risk factors for ocular sarcoidosis

Date:
May 20, 2014
Source:
American Thoracic Society (ATS)
Summary:
Cigarette smoking and male sex are significant risk factors for developing ocular sarcoidosis, according to a new study. Sarcoidosis is a disease in which inflammation produces tiny lumps of cells (called granulomas) in organs throughout the body, most often in the lungs, but also in the eyes, lymph nodes, or skin. Ocular sarcoidosis, which can lead to blindness, affects 25-50% of sarcoidosis patients.

Cigarette smoking and male sex are significant risk factors for developing ocular sarcoidosis, according to a new study presented at the 2014 American Thoracic Society International Conference.

Related Articles


Sarcoidosis is a disease in which inflammation produces tiny lumps of cells (called granulomas) in organs throughout the body, most often in the lungs, but also in the eyes, lymph nodes, or skin. Ocular sarcoidosis, which can lead to blindness, affects 25-50% of sarcoidosis patients.

"Risk factors for ocular sarcoidosis have not been well studied," said lead author Adam Janot, MD, of the Virginia Commonwealth University School of Medicine in Richmond. "Accordingly, we reviewed the cases of 109 patients with biopsy-proven sarcoidosis and identified independent risk factors for developing ocular morbidity."

Of the 109 patients, 21 had ocular sarcoidosis. A significantly higher percentage of patients with ocular sarcoidosis were smokers (71.4% vs 42.0%, p=0.027) and were male (57.1% vs 26.1%, p=0.009). Median duration of sarcoidosis was 10 years among patients with ocular sarcoidosis and 4 years among those without (p=0.031).

In analyses adjusting for age, race, sex, and other factors, tobacco exposure was associated with a greater than 5-fold risk of developing ocular sarcoidosis (odds ratio 5.24, p=0.007, 95% CI 1.58-17.41) and male sex was associated with a greater than 7-fold risk (odds ratio 7.48, p=0.002, 95% CI 2.152-26.006). Disease duration was no longer significantly associated with developing ocular sarcoidosis in the multivariate analysis. "Our study is the first to correlate smoking and male sex as risk factors for developing ocular manifestations of sarcoidosis," said Dr. Janot. "If confirmed in other studies, this information may give some insight into the pathology of the disease, can be useful in guiding treatment, and it adds ocular sarcoidosis to the numerous adverse health consequences of tobacco use."


Story Source:

The above story is based on materials provided by American Thoracic Society (ATS). Note: Materials may be edited for content and length.


Cite This Page:

American Thoracic Society (ATS). "Cigarette smoking, male sex: Risk factors for ocular sarcoidosis." ScienceDaily. ScienceDaily, 20 May 2014. <www.sciencedaily.com/releases/2014/05/140520122955.htm>.
American Thoracic Society (ATS). (2014, May 20). Cigarette smoking, male sex: Risk factors for ocular sarcoidosis. ScienceDaily. Retrieved November 25, 2014 from www.sciencedaily.com/releases/2014/05/140520122955.htm
American Thoracic Society (ATS). "Cigarette smoking, male sex: Risk factors for ocular sarcoidosis." ScienceDaily. www.sciencedaily.com/releases/2014/05/140520122955.htm (accessed November 25, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Tuesday, November 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

Newsy (Nov. 25, 2014) The US FDA is announcing new calorie rules on Tuesday that will require everywhere from theaters to vending machines to include calorie counts. Video provided by Newsy
Powered by NewsLook.com
Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Newsy (Nov. 25, 2014) Need another reason to eat yogurt every day? Researchers now say it could reduce a person's risk of developing type 2 diabetes. Video provided by Newsy
Powered by NewsLook.com
Madagascar Working to Contain Plague Outbreak

Madagascar Working to Contain Plague Outbreak

AFP (Nov. 24, 2014) Madagascar said Monday it is trying to contain an outbreak of plague -- similar to the Black Death that swept Medieval Europe -- that has killed 40 people and is spreading to the capital Antananarivo. Duration: 00:42 Video provided by AFP
Powered by NewsLook.com
Are Female Bosses More Likely To Be Depressed?

Are Female Bosses More Likely To Be Depressed?

Newsy (Nov. 24, 2014) A new study links greater authority with increased depressive symptoms among women in the workplace. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins