Featured Research

from universities, journals, and other organizations

Vitamin E in canola, other oils hurts lungs

Date:
May 20, 2014
Source:
Northwestern University
Summary:
A large new study advances our understanding of vitamin E and ties increasing consumption of supposedly healthy, vitamin E-rich oils -- canola, soybean and corn -- to the rising incidence of lung inflammation and, possibly, asthma. The good news: vitamin E in olive and sunflower oils improves lungs. The study shows drastically different health effects of vitamin E depending on its form: gamma-tocopherol in soybean, canola and corn oil and alpha-tocopherol in olive and sunflower oils.

A large new Northwestern Medicineฎ study upends our understanding of vitamin E and ties the increasing consumption of supposedly healthy vitamin E-rich oils -- canola, soybean and corn -- to the rising incidence of lung inflammation and, possibly, asthma.

Related Articles


The new study shows drastically different health effects of vitamin E depending on its form. The form of Vitamin E called gamma-tocopherol in the ubiquitous soybean, corn and canola oils is associated with decreased lung function in humans, the study reports. The other form of Vitamin E, alpha-tocopherol, which is found in olive and sunflower oils, does the opposite. It associated with better lung function.

"Considering the rate of affected people we found in this study, there could be 4.5 million individuals in the U.S. with reduced lung function as a result of their high gamma-tocopherol consumption," said senior author Joan Cook-Mills, an associate professor of medicine in allergy/immunology at Northwestern University Feinberg School of Medicine.

This is the first study to show gamma-tocopherol is associated with worse lung function.

Cook-Mills presented her research in May at the Oxidants and Antioxidants in Biology World Congress. It was also published in the journal Respiratory Research.

Rates of asthma in the U.S. have been climbing in the last 40 years, coinciding with a switch in U.S. diets from lard and butter to soybean, canola and corn oils, which were thought to be healthier for the heart. Looking at other countries' rates of asthma, Cook-Mills said those with significantly lower rates of asthma have diets high in olive and sunflower oils.

In the U.S., asthma prevalence (the percentage of people who have been diagnosed with asthma and still have asthma) was 8.4 percent in 2010, as reported by the U.S. Department of Health and Human Services Centers for Disease Control and Prevention.

In the U.S., the average blood plasma level of gamma-tocopherol is four or more times higher than those of European and Scandinavian countries that consume sunflower and olive oil, Cook-Mills noted.

"People in countries that consume olive and sunflower oil have the lowest rate of asthma and those that consume soybean, corn and canola oil have the highest rate of asthma," Cook-Mills said. "When people consume alpha-tocopherol, which is rich in olive oil and sunflower oil, their lung function is better."

The study examined 4,526 individuals from the Coronary Artery Risk Development in Young Adults Study (CARDIA). Cook-Mills had done previous allergy research in mice showing alpha-tocopherol decreased lung inflammation, protecting healthy lung function and gamma-tocopherol increased lung inflammation and airway hyperresponsiveness, a characteristic of asthma. She hypothesized that they might have similar effects in humans.

Cook-Mills examined the CARDIA results for individuals' lung function tests at four intervals from baseline to 20 years and the type of tocopherol levels in their blood plasma at three intervals from baseline to 15 years. She found that a high level of gamma-tocoperol, 10 micromolar in the blood plasma, was associated with a 10 to 17 percent reduction in lung function. Micromolar is a measure of the amount of gamma-tocopherol per liter volume of blood plasma.

"The blood plasma showed how much they had acquired in their tissues," Cook-Mills said. "You get vitamin E from your diet or supplements."

In 2012 research, she identified a mechanism for gamma-tocopherol increasing lung inflammation: protein kinase C-alpha, which binds both forms of vitamin E. Alpha-tocopherol inhibits the action of the protein and gamma-tocopherol increases the action of the protein.

"A 10 percent reduction in lung function is like an asthmatic condition," Cook-Mills said. "People have more trouble breathing. They take in less air, and it's harder to expel. Their lungs have reduced capacity."

People with asthma already have lower lung function, so if they have high gamma-tocopherol levels, they would have even more difficulty breathing, Cook-Mills said. The individuals in CARDIA with asthma and high gamma-tocopherol had the lowest lung function.

The study can be found online at: http://respiratory-research.com/content/pdf/1465-9921-15-31.pdf


Story Source:

The above story is based on materials provided by Northwestern University. Note: Materials may be edited for content and length.


Cite This Page:

Northwestern University. "Vitamin E in canola, other oils hurts lungs." ScienceDaily. ScienceDaily, 20 May 2014. <www.sciencedaily.com/releases/2014/05/140520220424.htm>.
Northwestern University. (2014, May 20). Vitamin E in canola, other oils hurts lungs. ScienceDaily. Retrieved December 19, 2014 from www.sciencedaily.com/releases/2014/05/140520220424.htm
Northwestern University. "Vitamin E in canola, other oils hurts lungs." ScienceDaily. www.sciencedaily.com/releases/2014/05/140520220424.htm (accessed December 19, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, December 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Best Tips to Curb Holiday Carbs

The Best Tips to Curb Holiday Carbs

Buzz60 (Dec. 19, 2014) — It's hard to resist those delicious but fattening carbs we all crave during the winter months, but there are some ways to stay satisfied without consuming the extra calories. Vanessa Freeman (@VanessaFreeTV) has the details. Video provided by Buzz60
Powered by NewsLook.com
Kids Die While Under Protective Services

Kids Die While Under Protective Services

AP (Dec. 18, 2014) — As part of a six-month investigation of child maltreatment deaths, the AP found that hundreds of deaths from horrific abuse and neglect could have been prevented. AP's Haven Daley reports. (Dec. 18) Video provided by AP
Powered by NewsLook.com
Dads-To-Be Also Experience Hormone Changes During Pregnancy

Dads-To-Be Also Experience Hormone Changes During Pregnancy

Newsy (Dec. 18, 2014) — A study from University of Michigan researchers found that expectant fathers see a decrease in testosterone as the baby's birth draws near. Video provided by Newsy
Powered by NewsLook.com
Prenatal Exposure To Pollution Might Increase Autism Risk

Prenatal Exposure To Pollution Might Increase Autism Risk

Newsy (Dec. 18, 2014) — Harvard researchers found children whose mothers were exposed to high pollution levels in the third trimester were twice as likely to develop autism. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins