Featured Research

from universities, journals, and other organizations

Vitamin E in canola, other oils hurts lungs

Date:
May 20, 2014
Source:
Northwestern University
Summary:
A large new study advances our understanding of vitamin E and ties increasing consumption of supposedly healthy, vitamin E-rich oils -- canola, soybean and corn -- to the rising incidence of lung inflammation and, possibly, asthma. The good news: vitamin E in olive and sunflower oils improves lungs. The study shows drastically different health effects of vitamin E depending on its form: gamma-tocopherol in soybean, canola and corn oil and alpha-tocopherol in olive and sunflower oils.

A large new Northwestern Medicineฎ study upends our understanding of vitamin E and ties the increasing consumption of supposedly healthy vitamin E-rich oils -- canola, soybean and corn -- to the rising incidence of lung inflammation and, possibly, asthma.

The new study shows drastically different health effects of vitamin E depending on its form. The form of Vitamin E called gamma-tocopherol in the ubiquitous soybean, corn and canola oils is associated with decreased lung function in humans, the study reports. The other form of Vitamin E, alpha-tocopherol, which is found in olive and sunflower oils, does the opposite. It associated with better lung function.

"Considering the rate of affected people we found in this study, there could be 4.5 million individuals in the U.S. with reduced lung function as a result of their high gamma-tocopherol consumption," said senior author Joan Cook-Mills, an associate professor of medicine in allergy/immunology at Northwestern University Feinberg School of Medicine.

This is the first study to show gamma-tocopherol is associated with worse lung function.

Cook-Mills presented her research in May at the Oxidants and Antioxidants in Biology World Congress. It was also published in the journal Respiratory Research.

Rates of asthma in the U.S. have been climbing in the last 40 years, coinciding with a switch in U.S. diets from lard and butter to soybean, canola and corn oils, which were thought to be healthier for the heart. Looking at other countries' rates of asthma, Cook-Mills said those with significantly lower rates of asthma have diets high in olive and sunflower oils.

In the U.S., asthma prevalence (the percentage of people who have been diagnosed with asthma and still have asthma) was 8.4 percent in 2010, as reported by the U.S. Department of Health and Human Services Centers for Disease Control and Prevention.

In the U.S., the average blood plasma level of gamma-tocopherol is four or more times higher than those of European and Scandinavian countries that consume sunflower and olive oil, Cook-Mills noted.

"People in countries that consume olive and sunflower oil have the lowest rate of asthma and those that consume soybean, corn and canola oil have the highest rate of asthma," Cook-Mills said. "When people consume alpha-tocopherol, which is rich in olive oil and sunflower oil, their lung function is better."

The study examined 4,526 individuals from the Coronary Artery Risk Development in Young Adults Study (CARDIA). Cook-Mills had done previous allergy research in mice showing alpha-tocopherol decreased lung inflammation, protecting healthy lung function and gamma-tocopherol increased lung inflammation and airway hyperresponsiveness, a characteristic of asthma. She hypothesized that they might have similar effects in humans.

Cook-Mills examined the CARDIA results for individuals' lung function tests at four intervals from baseline to 20 years and the type of tocopherol levels in their blood plasma at three intervals from baseline to 15 years. She found that a high level of gamma-tocoperol, 10 micromolar in the blood plasma, was associated with a 10 to 17 percent reduction in lung function. Micromolar is a measure of the amount of gamma-tocopherol per liter volume of blood plasma.

"The blood plasma showed how much they had acquired in their tissues," Cook-Mills said. "You get vitamin E from your diet or supplements."

In 2012 research, she identified a mechanism for gamma-tocopherol increasing lung inflammation: protein kinase C-alpha, which binds both forms of vitamin E. Alpha-tocopherol inhibits the action of the protein and gamma-tocopherol increases the action of the protein.

"A 10 percent reduction in lung function is like an asthmatic condition," Cook-Mills said. "People have more trouble breathing. They take in less air, and it's harder to expel. Their lungs have reduced capacity."

People with asthma already have lower lung function, so if they have high gamma-tocopherol levels, they would have even more difficulty breathing, Cook-Mills said. The individuals in CARDIA with asthma and high gamma-tocopherol had the lowest lung function.

The study can be found online at: http://respiratory-research.com/content/pdf/1465-9921-15-31.pdf


Story Source:

The above story is based on materials provided by Northwestern University. Note: Materials may be edited for content and length.


Cite This Page:

Northwestern University. "Vitamin E in canola, other oils hurts lungs." ScienceDaily. ScienceDaily, 20 May 2014. <www.sciencedaily.com/releases/2014/05/140520220424.htm>.
Northwestern University. (2014, May 20). Vitamin E in canola, other oils hurts lungs. ScienceDaily. Retrieved July 29, 2014 from www.sciencedaily.com/releases/2014/05/140520220424.htm
Northwestern University. "Vitamin E in canola, other oils hurts lungs." ScienceDaily. www.sciencedaily.com/releases/2014/05/140520220424.htm (accessed July 29, 2014).

Share This




More Health & Medicine News

Tuesday, July 29, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Deadly Ebola Virus Threatens West Africa

Deadly Ebola Virus Threatens West Africa

AP (July 28, 2014) — West African nations and international health organizations are working to contain the largest Ebola outbreak in history. It's one of the deadliest diseases known to man, but the CDC says it's unlikely to spread in the U.S. (July 28) Video provided by AP
Powered by NewsLook.com
$15B Deal on Vets' Health Care Reached

$15B Deal on Vets' Health Care Reached

AP (July 28, 2014) — A bipartisan deal to improve veterans health care would authorize at least $15 billion in emergency spending to fix a veterans program scandalized by long patient wait times and falsified records. (July 28) Video provided by AP
Powered by NewsLook.com
Two Americans Contract Ebola in Liberia

Two Americans Contract Ebola in Liberia

Reuters - US Online Video (July 28, 2014) — Two American aid workers in Liberia test positive for Ebola while working to combat the deadliest outbreak of the virus ever. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Traditional African Dishes Teach Healthy Eating

Traditional African Dishes Teach Healthy Eating

AP (July 28, 2014) — Classes are being offered nationwide to encourage African Americans to learn about cooking fresh foods based on traditional African cuisine. The program is trying to combat obesity, heart disease and other ailments often linked to diet. (July 28) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins