Featured Research

from universities, journals, and other organizations

Telephone call is effective support when breast cancer treatment includes weight loss

Date:
June 19, 2014
Source:
Lunenfeld-Tanenbaum Research Institute
Summary:
A series of simple telephone calls can make a profound difference in helping women to meet their treatment goals for breast cancer, according to a randomized trial of women who are also obese. Women who received advice about weight loss from a trained lifestyle coach by telephone achieved weight loss that was still evident after two years, lowering their risk of breast cancer recurrence.

A series of simple telephone calls can make a profound difference in helping women to meet their treatment goals for breast cancer, according to a randomized trial of women who are also obese, published online today in Journal of Clinical Oncology by Dr. Pamela Goodwin of Mount Sinai Hospital and the Lunenfeld-Tanenbaum Research Institute.

Related Articles


Women who received advice about weight loss from a trained lifestyle coach by telephone achieved weight loss that was still evident after two years, lowering their risk of breast cancer recurrence.

It's already known that women who are obese have about a 25-30% greater risk of death compared to women who are not obese, says Dr. Goodwin. Excess fat tissue in the body stimulates inflammation, and is associated with alterations in hormones such as insulin, leptin, and estradiol, which play a part in cancer growth and recurrence. "That's why breast cancer treatment for women who are overweight often includes weight loss as an important treatment goal," she adds. Dr. Goodwin is the Director of Mount Sinai's Marvelle Koffler Breast Centre, an investigator at theLunenfeld-Tanenbaum research Institute at Mount Sinai Hospital, and a Professor in the Department of Medicine at University of Toronto.

Low-cost intervention

"This study demonstrates a powerful result for lifestyle change that is notoriously challenging," Dr. Goodwin explains. "As much as we look to the technology and medical side of treatment, it's just as vital to understand the power of low-cost interventions that can make difference in breast cancer survival and quality of life," she adds.

The randomized trial of 338 women in Canada and the US compared results in women who received advice about weight loss from a lifestyle coach on the telephone to results in women who received a mailing. All the study participants were post-menopausal and received an aromatase inhibitor (estrogen blocker). The results in terms of sustained weight loss after two years were comparable to that achieved by women who had an in-person consultation about weight loss.

"For women who face the compounded challenge of breast cancer and obesity, we can't ignore the importance of low-cost supports to that may contribute to improved survival," says Dr. Goodwin. Large-scale randomized trials are being planned to investigate effects of a telephone-based weight loss intervention on breast cancer outcomes.

The paper is "A randomized trial of a telephone-based weight loss intervention in postmenopausal women with breast cancer receiving letrozole: The LISA Trial," with coauthors across Canada and at Harvard Medical School. Funders include Lunenfeld-Tanenbaum Research Institute and Mount Sinai Hospital Foundation.


Story Source:

The above story is based on materials provided by Lunenfeld-Tanenbaum Research Institute. Note: Materials may be edited for content and length.


Journal Reference:

  1. P. J. Goodwin, R. J. Segal, M. Vallis, J. A. Ligibel, G. R. Pond, A. Robidoux, G. L. Blackburn, B. Findlay, J. R. Gralow, S. Mukherjee, M. Levine, K. I. Pritchard. Randomized Trial of a Telephone-Based Weight Loss Intervention in Postmenopausal Women With Breast Cancer Receiving Letrozole: The LISA Trial. Journal of Clinical Oncology, 2014; DOI: 10.1200/JCO.2013.53.1517

Cite This Page:

Lunenfeld-Tanenbaum Research Institute. "Telephone call is effective support when breast cancer treatment includes weight loss." ScienceDaily. ScienceDaily, 19 June 2014. <www.sciencedaily.com/releases/2014/06/140619095930.htm>.
Lunenfeld-Tanenbaum Research Institute. (2014, June 19). Telephone call is effective support when breast cancer treatment includes weight loss. ScienceDaily. Retrieved October 31, 2014 from www.sciencedaily.com/releases/2014/06/140619095930.htm
Lunenfeld-Tanenbaum Research Institute. "Telephone call is effective support when breast cancer treatment includes weight loss." ScienceDaily. www.sciencedaily.com/releases/2014/06/140619095930.htm (accessed October 31, 2014).

Share This



More Health & Medicine News

Friday, October 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Melafind: Spotting Melanoma Without a Biopsy

Melafind: Spotting Melanoma Without a Biopsy

Ivanhoe (Oct. 31, 2014) The MelaFind device is a pain-free way to check suspicious moles for melanoma, without the need for a biopsy. Video provided by Ivanhoe
Powered by NewsLook.com
Battling Multiple Myeloma

Battling Multiple Myeloma

Ivanhoe (Oct. 31, 2014) The answer isn’t always found in new drugs – repurposing an ‘old’ drug that could mean better multiple myeloma treatment, and hope. Video provided by Ivanhoe
Powered by NewsLook.com
Chronic Inflammation and Prostate Cancer

Chronic Inflammation and Prostate Cancer

Ivanhoe (Oct. 31, 2014) New information that is linking chronic inflammation in the prostate and prostate cancer, which may help doctors and patients prevent cancer in the future. Video provided by Ivanhoe
Powered by NewsLook.com
Sickle Cell: Stopping Kids’ Silent Strokes

Sickle Cell: Stopping Kids’ Silent Strokes

Ivanhoe (Oct. 31, 2014) Blood transfusions are proving crucial to young sickle cell patients by helping prevent strokes, even when there is no outward sign of brain injury. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins