Featured Research

from universities, journals, and other organizations

Soy supplements appear to be safe, beneficial in diabetic men

Date:
June 23, 2014
Source:
Endocrine Society
Summary:
Soy protein supplements, which contain natural estrogens, do not reduce testosterone levels in men with Type 2 diabetes who already have borderline-low testosterone, according to a new study. In addition, soy protein supplements significantly improved diastolic blood pressure (the bottom number in a blood pressure reading) but not systolic blood pressure (the top number).

Soy protein supplements, which contain natural estrogens, do not reduce testosterone levels in men with Type 2 diabetes who already have borderline-low testosterone, according to a new study. The results were presented Saturday at the joint meeting of the International Society of Endocrinology and the Endocrine Society: ICE/ENDO 2014 in Chicago.

"Because soy contains phytoestrogens that are similar to the female hormone estrogen, it was not known whether consumption of soy could reduce testosterone levels in men with Type 2 diabetes, who are at increased risk of low testosterone," said the study's lead investigator, Thozhukat Sathyapalan, MD, an endocrinologist researcher at Hull York Medical School, University of Hull, Hull, U.K.

"It was important to know this because prior studies have found that daily consumption of soy reduces the risk of Type 2 diabetes and heart problems. Our study found that soy protein and phytoestrogen supplementation is safe in diabetic men and may improve their diabetes control and their risk factors for heart disease," Sathyapalan said.

Their study included 210 men ages 55 to 70 who had Type 2 diabetes and a borderline-low total testosterone level: less than or equal to 12 nanomoles per liter (nmol/L) or 345.8 nanograms per deciliter. For three months, the men ate two cereal bars a day, each containing 30 grams of soy protein. The bars in one group of 100 men contained 66 milligrams of soy phytoestrogens, which is equivalent to the amount in soy supplements or in a typical Southeast Asian diet. The second group of 100 men received soy protein bars in which phytoestrogens were removed. Patients were asked to avoid eating foods containing soy.

The men had testosterone blood tests before and after treatment at the same time of day. Both groups experienced an increase in total testosterone level, the investigators reported. On average, testosterone level increased from 9.8 to 11.3 nmol/L in the soy protein-phytoestrogen group and from 9.2 to 10.3 nmol/L in the group receiving only soy protein.

Sathyapalan said it is unclear why testosterone levels rose, but it could be a direct effect of soy.

Soy protein with phytoestrogens also improved diabetes control much better than did soy protein alone. Specifically, the first group significantly lowered their fasting blood glucose (sugar) levels and hemoglobin A1c, a measure of blood sugar control over the past three months, as well as fasting insulin levels and estimated insulin resistance, which showed an improved use of the hormone insulin. Neither group lost or gained weight, according to Sathyapalan.

In addition, the phytoestrogen-containing soy protein reportedly led to better improvements in certain cardiovascular risk factors, he said. These included triglycerides -- a type of fat in the blood -- and high-sensitivity C-reactive protein, which measures inflammation in the body and is a predictor of heart disease risk. Total cholesterol and "bad" (LDL) cholesterol levels rose (worsened) in both groups but not enough to be statistically significant, according to Sathyapalan.

Both soy protein supplements significantly improved diastolic blood pressure (the bottom number in a blood pressure reading) but not systolic blood pressure (the top number).


Story Source:

The above story is based on materials provided by Endocrine Society. Note: Materials may be edited for content and length.


Cite This Page:

Endocrine Society. "Soy supplements appear to be safe, beneficial in diabetic men." ScienceDaily. ScienceDaily, 23 June 2014. <www.sciencedaily.com/releases/2014/06/140623092013.htm>.
Endocrine Society. (2014, June 23). Soy supplements appear to be safe, beneficial in diabetic men. ScienceDaily. Retrieved September 21, 2014 from www.sciencedaily.com/releases/2014/06/140623092013.htm
Endocrine Society. "Soy supplements appear to be safe, beneficial in diabetic men." ScienceDaily. www.sciencedaily.com/releases/2014/06/140623092013.htm (accessed September 21, 2014).

Share This



More Health & Medicine News

Sunday, September 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Sierra Leone in Lockdown to Control Ebola

Sierra Leone in Lockdown to Control Ebola

AP (Sep. 21, 2014) Sierra Leone residents remained in lockdown on Saturday as part of a massive effort to confine millions of people to their homes in a bid to stem the biggest Ebola outbreak in history. (Sept. 20) Video provided by AP
Powered by NewsLook.com
Sierra Leone's Nationwide Ebola Curfew Underway

Sierra Leone's Nationwide Ebola Curfew Underway

Newsy (Sep. 20, 2014) Sierra Leone is locked down as aid workers and volunteers look for new cases of Ebola. Video provided by Newsy
Powered by NewsLook.com
Changes Found In Brain After One Dose Of Antidepressants

Changes Found In Brain After One Dose Of Antidepressants

Newsy (Sep. 19, 2014) A study suggest antidepressants can kick in much sooner than previously thought. Video provided by Newsy
Powered by NewsLook.com
Could Grief Affect The Immune Systems Of Senior Citizens?

Could Grief Affect The Immune Systems Of Senior Citizens?

Newsy (Sep. 19, 2014) The study found elderly people are much more likely to become susceptible to infection than younger adults going though a similar situation. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins