Featured Research

from universities, journals, and other organizations

Individuals who are extremely obese have higher rates of mortality

Date:
July 8, 2014
Source:
PLOS
Summary:
Class III obesity is linked to higher rates of mortality, according to a new study. Medical researchers found that mortality rates for a wide range of diseases, particularly heart disease, cancer, and diabetes, were higher in individuals with class III obesity compared to those in the normal weight range.

Class III obesity (BMI greater than 40 kg/m2) is linked to higher rates of mortality, according to a study published in this week's PLOS Medicine. Cari Kitahara and colleagues from National Cancer Institute, US, found that mortality rates for a wide range of diseases, particularly heart disease, cancer, and diabetes, were higher in individuals with class III obesity compared to those in the normal weight range.

Related Articles


The researchers reached these conclusions by pooling data from 20 prospective (mainly US) cohort studies from the National Cancer Institute Cohort Consortium. After excluding individuals who had ever smoked and people with a history of chronic disease, the analysis included 9,564 adults who were classified as class III obese based on self-reported height and weight at baseline and 304,011 normal-weight adults. Among the participants with class III obesity, mortality rates (deaths per 100,000 persons per year) during the 30-year study period were 856.0 and 663.0 for men and women, respectively, whereas the mortality rates among normal-weight men and women were 346.7 and 280.5, respectively. Heart disease was the major contributor to the higher mortality rate among class III obese individuals, followed by cancer and diabetes. Furthermore, the risk of all-cause death and death due to heart disease, cancer, diabetes, and several other diseases increased with increasing BMI. Compared with having a normal weight, having a BMI between 40 and 59 kg/m2 resulted in an estimated loss of 6.5 to 13.7 years of life.

The accuracy of these findings is limited by the use of mostly self-reported height and weight measurements to calculate BMI and by the use of BMI as the sole measure of obesity. These findings may not be generalizable to all populations. Nevertheless, these findings indicate that class III obesity is associated with a substantially increased rate of death and highlight the need to develop more effective interventions to reduce class III obesity.

The authors say: "Class III obesity is associated with excess rates of total mortality and mortality due to a wide range of causes, particularly heart disease, cancer, and diabetes, and that the risk of death overall and from these specific causes continues to rise with increasing values of BMI."

They continue: "We found that the reduction in life expectancy associated with class III obesity was similar to (and, for BMI values above 50 kg/m2, even greater than) that observed for current smoking."


Story Source:

The above story is based on materials provided by PLOS. Note: Materials may be edited for content and length.


Journal Reference:

  1. Cari M. Kitahara, Alan J. Flint, Amy Berrington de Gonzalez, Leslie Bernstein, Michelle Brotzman, Robert J. MacInnis, Steven C. Moore, Kim Robien, Philip S. Rosenberg, Pramil N. Singh, Elisabete Weiderpass, Hans Olov Adami, Hoda Anton-Culver, Rachel Ballard-Barbash, Julie E. Buring, D. Michal Freedman, Gary E. Fraser, Laura E. Beane Freeman, Susan M. Gapstur, John Michael Gaziano, Graham G. Giles, Niclas Hεkansson, Jane A. Hoppin, Frank B. Hu, Karen Koenig, Martha S. Linet, Yikyung Park, Alpa V. Patel, Mark P. Purdue, Catherine Schairer, Howard D. Sesso, Kala Visvanathan, Emily White, Alicja Wolk, Anne Zeleniuch-Jacquotte, Patricia Hartge. Association between Class III Obesity (BMI of 40–59 kg/m2) and Mortality: A Pooled Analysis of 20 Prospective Studies. PLoS Medicine, 2014; 11 (7): e1001673 DOI: 10.1371/journal.pmed.1001673

Cite This Page:

PLOS. "Individuals who are extremely obese have higher rates of mortality." ScienceDaily. ScienceDaily, 8 July 2014. <www.sciencedaily.com/releases/2014/07/140708153858.htm>.
PLOS. (2014, July 8). Individuals who are extremely obese have higher rates of mortality. ScienceDaily. Retrieved October 31, 2014 from www.sciencedaily.com/releases/2014/07/140708153858.htm
PLOS. "Individuals who are extremely obese have higher rates of mortality." ScienceDaily. www.sciencedaily.com/releases/2014/07/140708153858.htm (accessed October 31, 2014).

Share This



More Health & Medicine News

Friday, October 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Melafind: Spotting Melanoma Without a Biopsy

Melafind: Spotting Melanoma Without a Biopsy

Ivanhoe (Oct. 31, 2014) — The MelaFind device is a pain-free way to check suspicious moles for melanoma, without the need for a biopsy. Video provided by Ivanhoe
Powered by NewsLook.com
Battling Multiple Myeloma

Battling Multiple Myeloma

Ivanhoe (Oct. 31, 2014) — The answer isn’t always found in new drugs – repurposing an ‘old’ drug that could mean better multiple myeloma treatment, and hope. Video provided by Ivanhoe
Powered by NewsLook.com
Chronic Inflammation and Prostate Cancer

Chronic Inflammation and Prostate Cancer

Ivanhoe (Oct. 31, 2014) — New information that is linking chronic inflammation in the prostate and prostate cancer, which may help doctors and patients prevent cancer in the future. Video provided by Ivanhoe
Powered by NewsLook.com
Sickle Cell: Stopping Kids’ Silent Strokes

Sickle Cell: Stopping Kids’ Silent Strokes

Ivanhoe (Oct. 31, 2014) — Blood transfusions are proving crucial to young sickle cell patients by helping prevent strokes, even when there is no outward sign of brain injury. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

More Coverage


Extreme Obesity May Shorten Life Expectancy Up to 14 Years

July 8, 2014 — Adults with extreme obesity have increased risks of dying at a young age from cancer and many other causes including heart disease, stroke, diabetes, and kidney and liver diseases, according to ... read more

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins