Featured Research

from universities, journals, and other organizations

Integrons hold key to antibiotic resistance crisis

Date:
August 12, 2014
Source:
Investigación y Desarrollo
Summary:
In Mexico, the sale of antibiotics for human consumption is controlled to prevent misuse, although in the veterinary sector failure in the implementation of the "Guidelines for veterinarian products prescription”, has prompted common bacteria such as Escherichia coli and Salmonella to become resistant to regular drugs such as streptomycin, trimethoprim, ampicillin, gentamicin, and tetracycline as a result of excess drug use.

In Mexico the sale of antibiotics for human consumption is controlled to prevent misuse, although in the veterinary sector failure in the implementation of the Official Mexican Standard NOM-064-ZOO-2000, "Guidelines for veterinarian products prescription," has prompted common bacteria such as Escherichia coli and Salmonella spp to become resistant to regular drugs such as streptomycin, trimethoprim, ampicillin, gentamicin, and tetracycline as a result of excess drug use.

Related Articles


The use of antibiotics without prescription for veterinary use is a problem that may seem minimal, but the importance is that each improper administration of these drugs, is conducive to bacteria normally present in the intestinal tract of animals are being subjected to a selective pressure, causing them to acquire different mechanisms for its survival.

In order to discover the origin of bacterial resistance, Martín Talavera Rojas, professor at the Centre for Research and Advanced Studies in Animal Health of the Autonomous University of the State of Mexico (UAEM), analyzed different isolates of bacteria from animals for human consumption and reports that such resistance is due to the presence of various resistance genes specific for each class of antibiotics.

The results of the studies were used to detect the presence of genetic fragments (integrons) that cause resistance to various antibiotics, due to the insertion of genes in these structures, which results in increased resistance and prevent income of bactericidal agents, said the scientists.

The cause of bacterial strains that have become more resistant to drugs is that there is not a controlled sale of antibiotics in veterinary and in using them indiscriminately causing bacteria acquire resistance factors that allow it to survive affecting food production.

UAEM researcher concluded that the damage caused by the infection "superbugs" such as Escherichia coli serovar O157: H7 causes bloody diarrhea, severe abdominal pain and in some cases can cause kidney and neurological complications, including uremic syndrome hemolytic; while Salmonella causes bleeding blood and fever.

Talavera Rojas said the isolates of Salmonella spp where resistant to various antibiotics and integrons were present in 40 percent of the isolates (31/77). Afterwards the bacteria were subjected to trimethoprim-sulfa antibiotics, tetracycline, ampicillin, and streptomycin, to check resistance to these drugs.


Story Source:

The above story is based on materials provided by Investigación y Desarrollo. Note: Materials may be edited for content and length.


Cite This Page:

Investigación y Desarrollo. "Integrons hold key to antibiotic resistance crisis." ScienceDaily. ScienceDaily, 12 August 2014. <www.sciencedaily.com/releases/2014/08/140812121735.htm>.
Investigación y Desarrollo. (2014, August 12). Integrons hold key to antibiotic resistance crisis. ScienceDaily. Retrieved November 29, 2014 from www.sciencedaily.com/releases/2014/08/140812121735.htm
Investigación y Desarrollo. "Integrons hold key to antibiotic resistance crisis." ScienceDaily. www.sciencedaily.com/releases/2014/08/140812121735.htm (accessed November 29, 2014).

Share This


More From ScienceDaily



More Plants & Animals News

Saturday, November 29, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Research on Bats Could Help Develop Drugs Against Ebola

Research on Bats Could Help Develop Drugs Against Ebola

AFP (Nov. 28, 2014) — In Africa's only biosafety level 4 laboratory, scientists have been carrying out experiments on bats to understand how virus like Ebola are being transmitted, and how some of them resist to it. Duration: 01:18 Video provided by AFP
Powered by NewsLook.com
New Dinosaur Species Found in Museum Collection

New Dinosaur Species Found in Museum Collection

Reuters - Innovations Video Online (Nov. 27, 2014) — A British palaeontologist has discovered a new species of dinosaur while studying fossils in a Canadian museum. Pentaceratops aquilonius was related to Triceratops and lived at the end of the Cretaceous Period, around 75 million years ago. Jim Drury has more. Video provided by Reuters
Powered by NewsLook.com
Tryptophan Isn't Making You Sleepy On Thanksgiving

Tryptophan Isn't Making You Sleepy On Thanksgiving

Newsy (Nov. 27, 2014) — Tryptophan, a chemical found naturally in turkey meat, gets blamed for sleepiness after Thanksgiving meals. But science points to other culprits. Video provided by Newsy
Powered by NewsLook.com
Classic Hollywood Memorabilia Goes Under the Hammer

Classic Hollywood Memorabilia Goes Under the Hammer

Reuters - Entertainment Video Online (Nov. 26, 2014) — The iconic piano from "Casablanca" and the Cowardly Lion suit from "The Wizard of Oz" fetch millions at auction. Sara Hemrajani reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins