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Lung cancer metastases may travel through airways to adjacent or distant lung tissue

Date:
December 30, 2014
Source:
American Roentgen Ray Society
Summary:
A new study supports the hypothesis that lung cancer, particularly adenocarcinoma, may spread through the airways. The putative occurrence of intrapulmonary aerogenous metastasis of lung cancer has staging, management, and prognostic implications.
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A new study by researchers in Canada supports the hypothesis that lung cancer, particularly adenocarcinoma, may spread through the airways. The putative occurrence of intrapulmonary aerogenous metastasis of lung cancer has staging, management, and prognostic implications.

Lung cancer is the most common and most lethal cancer worldwide. Its prognosis remains poor: The 5-year survival rate is 6-18%. Adenocarcinoma has surpassed squamous cell carcinoma as the leading histologic type, accounting for 30% of all cases of lung cancer. Hematogenous spread (i.e., carried by blood) is the most common mechanism of intrapulmonary metastasis. Although local venous spread can occur, systemic spread with secondary lung involvement is much more common.

"Cumulative evidence suggests that intrapulmonary aerogenous spread may exist and is underrecognized," say the authors of "Aerogenous Metastases: A Potential Game Changer in the Diagnosis and Management of Primary Lung Adenocarcinoma," published in the December 2014 issue of the American Journal of Roentgenology. "Aerogenous metastases must be differentiated from multiple synchronous lesions in the spectrum of lung adenocarcinoma, [and] imaging features are helpful in differentiating possible aerogenous spread of tumor."


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Materials provided by American Roentgen Ray Society. Note: Content may be edited for style and length.


Journal Reference:

  1. Anand Gaikwad, Carolina A. Souza, Joao R. Inacio, Ashish Gupta, Harmanjatinder S. Sekhon, Jean M. Seely, Carole Dennie, Marcio M. Gomes. Aerogenous Metastases: A Potential Game Changer in the Diagnosis and Management of Primary Lung Adenocarcinoma. American Journal of Roentgenology, 2014; 203 (6): W570 DOI: 10.2214/AJR.13.12088

Cite This Page:

American Roentgen Ray Society. "Lung cancer metastases may travel through airways to adjacent or distant lung tissue." ScienceDaily. ScienceDaily, 30 December 2014. <www.sciencedaily.com/releases/2014/12/141230101915.htm>.
American Roentgen Ray Society. (2014, December 30). Lung cancer metastases may travel through airways to adjacent or distant lung tissue. ScienceDaily. Retrieved June 18, 2024 from www.sciencedaily.com/releases/2014/12/141230101915.htm
American Roentgen Ray Society. "Lung cancer metastases may travel through airways to adjacent or distant lung tissue." ScienceDaily. www.sciencedaily.com/releases/2014/12/141230101915.htm (accessed June 18, 2024).

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