Personalized Medicine News
April 29, 2016

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updated 7:34pm EDT

More Personalized Medicine News
April 29, 2016

Apr. 18, 2016 — Cancer is rarely the result of a single mutation in a single gene. Rather, tumors arise from the complex interplay between any number of mutually exclusive abnormal changes in the genome, the ... read more

Apr. 15, 2016 — As medical professionals search for new ways to personalize diagnosis and treatment of disease, researchers have already put into practice what may be the next big step in precision medicine: ... read more

Study Uncovers Genetic Variation That Predicted Type and Rate of Physical Decline in Patients With Parkinson's Disease

Apr. 14, 2016 — A site of genetic variation has been found that identified which patients with Parkinson's disease are more likely to have tremors versus difficulty with balance and walking. The team also found ... read more

Specific Gene in the Tumor Determines the Effectiveness of Cancer Treatment

Apr. 14, 2016 — A cancer treatment can be basically effective but, equally, it may have negative consequences. Therefore, it has not been possible to determine prior to treatment whether a patient will benefit from ... read more

Researchers Discover Liver Metastases Have Different Radiation Sensitivities

Apr. 12, 2016 — Radiation is a commonly used therapeutic option to treat liver metastases, with the majority of tumors maintained under control after one year. However, some patients do not respond as well to ... read more

Apr. 11, 2016 — When a targeted therapy blocks a pathway that enables tumors to grow, the cells usually manage to get around that obstacle. The result is drug resistance. Researchers have now found a way to map ... read more

Apr. 6, 2016 — A new computational tool successfully tested in a small pilot trial harnesses clinical data to predict the optimal drug dose for an ... read more

Precision Medicine Brings New Hope to Those With Advanced Urothelial Cancer

Apr. 4, 2016 — Five of six patients with advanced metastatic urothelial cancer and one of two specific genetic abnormalities responded to treatment with afatinib, approved in 2013 for lung cancer. One patient with ... read more

Personalized Ratings App May Improve Patient’s Choice of Nursing Home

Apr. 4, 2016 — A new app can improve a patient’s choice of a nursing home. This is important, because when rating quality measures for nursing homes, patients and experts at the Centers for Medicare and Medicaid ... read more

Landmark Study May Pave Way for Personalized Treatment of Lupus, Other Complex Autoimmune Diseases

Mar. 31, 2016 — New research that may dramatically improve drug development for systemic lupus erythematosus patients has been released by researchers. Lupus is a chronic disease that causes the body’s immune ... read more

Gene Variant May Contribute to Increased Cancer Risk in African-Americans

Mar. 30, 2016 — New research has pinpointed a single variant in a gene that is only found in Africans and African-Americans, which makes cancer resistant to cell death and may contribute to increased cancer ... read more

Individualized Treatment Duration of Blood Thinning Drugs After Heart Stent Procedures

Mar. 29, 2016 — Nearly 1 million people in the United States receive coronary artery stents each year. Nearly all stent patients are expected to take dual antiplatelet therapy (DAPT) using the combination of aspirin ... read more

Model of Tumor Spreading May Help Doctors Pinpoint Best Treatment

Mar. 23, 2016 — Scientists have invented a “metastasis-on-a-chip” system believed to be one of the first laboratory models of cancer spreading from one 3D tissue to another. They hope the technology can one day ... read more

More Cost-Effective Cure for Hepatitis C May Be Close

Mar. 22, 2016 — The cost of treating hepatitis C virus could be cut up to 50 percent if mathematical models are used to predict when patients can safely stop taking direct-acting antiviral medication, according to a ... read more

Precision Medicine's Potential to Define the Genetics of Autoimmune Disease

Mar. 18, 2016 — Demonstrating the potential of precision medicine, an international study used next-generation DNA sequencing technology to identify more than 1,000 gene variants that affect susceptibility to ... read more

New Recessive Disease Identified

Mar. 17, 2016 — Each gene variation has the potential to trigger specific defects. Among all genetic conditions, diseases recessive occur only when both the father and the mother are healthy carriers of the same ... read more

Genomic Profiling Helps Provide Targeted Therapy Options for Hard to Treat Cancers

Mar. 16, 2016 — Research examining difficult to treat tumors through genomic profiling shows that tumors with alterations in a signaling pathway responsible for cell regulation may respond to targeted therapy ... read more

Mar. 14, 2016 — Colorectal cancer, one of the most commonly diagnosed cancers in the United States, is not a commonly discussed disease. Often symptom-less in early stages, the cancer is more difficult to treat as ... read more

Mar. 14, 2016 — What have historically been considered three major types of kidney cancer according to their histological characteristic, can be further distinguished into nine major subtypes through molecular ... read more

Gene May Worsen Cancer Outcome by Speeding Metabolism of Drugs

Mar. 10, 2016 — Some patients with breast cancer, lung cancer and leukemia seem to fare poorly after treatment because of the effects of a particular gene, a new study finds. The gene, called CYP3A7, is normally ... read more

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