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H. pylori infection may reduce risk of allergic esophageal condition

Date:
March 1, 2016
Source:
Wiley
Summary:
New research suggests that Helicobacter pylori (H. pylori) infection of the stomach, which occurs in about half of the world's population and can cause peptic ulcers and stomach cancer in minority of cases, may help protect against an allergic disorder of the esophagus condition called eosinophilic esophagitis.
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New research suggests that Helicobacter pylori (H. pylori) infection of the stomach, which occurs in about half of the world's population and can cause peptic ulcers and stomach cancer in minority of cases, may help protect against an allergic disorder of the esophagus condition called eosinophilic esophagitis (EoE).

In a study of 58 adults with EoE and 116 aged- and sex-matched controls, H. pylori infection was inversely associated with EoE. The prevalence of H. pylori in the control group was 37.9%, whereas 3 EoE patients (5.2%) were currently infected with H. pylori and 5 EoE patients (8.6%) reported prior eradication of H. pylori. H. pylori infection was linked with a 76% reduced likelihood of having EoE.

"This adds to the evidence that allergic disorders in general may be less common in people with H. pylori infection," said lead author Dr. Ulrike von Aarnim, of the University of Magdeburg, in Germany. The results are published in Alimentary Pharmacology & Therapeutics.


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Journal Reference:

  1. U. von Arnim, T. Wex, A. Link, M. Messerschmidt, M. Venerito, S. Miehlke, P. Malfertheiner. Helicobacter pyloriinfection is associated with a reduced risk of developing eosinophilic oesophagitis. Alimentary Pharmacology & Therapeutics, 2016; DOI: 10.1111/apt.13560

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Wiley. "H. pylori infection may reduce risk of allergic esophageal condition." ScienceDaily. ScienceDaily, 1 March 2016. <www.sciencedaily.com/releases/2016/03/160301174801.htm>.
Wiley. (2016, March 1). H. pylori infection may reduce risk of allergic esophageal condition. ScienceDaily. Retrieved December 9, 2024 from www.sciencedaily.com/releases/2016/03/160301174801.htm
Wiley. "H. pylori infection may reduce risk of allergic esophageal condition." ScienceDaily. www.sciencedaily.com/releases/2016/03/160301174801.htm (accessed December 9, 2024).

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