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New cardiac pump device more effective, less costly than standard pump

Analysis of data from MOMENTUM 3 trial finds Heartmate 3 can minimize cost of care over time for heart failure patients

Date:
June 4, 2018
Source:
Brigham and Women's Hospital
Summary:
Investigators presented evidence that a next-generation cardiac pump device not only improves long-term outcomes but may also decrease cost of care over time for heart failure patients.
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In a presentation at the annual meeting of the Heart Failure Association of the European Society of Cardiology, and in a simultaneous publication in Circulation, investigators from Brigham and Women's Hospital presented evidence that a next-generation cardiac pump device not only improves long-term outcomes but may also decrease cost of care over time for heart failure patients. The research team analyzed results from the MOMENTUM 3 trial, which compared two devices: The HeartMate II (current generation) and HeartMate 3 (a novel, centrifugal-flow pump), both manufactured by Abbott, Inc., which sponsored the study.

"The HeartMate 3 left-ventricular assist device (LVAD) is a more forgiving pump in terms of clinical adverse events, and now we can confirm that its increased effectiveness is associated with decreased costs," said Mandeep Mehra, MD, executive director of the Center for Advanced Heart Disease and medical director of the Heart & Vascular Center at Brigham and Women's Hospital. "In medicine, most often, a therapy that demonstrates increased effectiveness usually comes at a higher price, and we are able to show that this new technology actually decreases costs to payers and patients over time."

Mehra and colleagues found that the newer device reduced costs due to re-hospitalization by 51 percent, largely driven by a decrease in stroke and pump malfunction requiring reoperation due to pump thrombosis. Patients who received the HeartMate 3 experienced fewer hospitalizations and, on average, spent 8.3 fewer days in the hospital per year than those who received the HeartMate II. The authors note that it may be possible to further reduce costs by decreasing outlier complications and reducing hospital length of stay, and decrease early complications by improving patient selection criteria and considering this therapy before patients get too sick.

In April, Abbott Inc. issued a field safety notice regarding HeartMate 3 outflow graft twist complications with an incidence rate of 0.72 percent. The FDA issued a Class I recall but did not recommend the return of LVADs or avoidance of use in new patients. The current study re-reviewed 20 hospitalizations (five in the HeartMate 3 and 15 in the HeartMate II populations) and in a conservative analysis, classified them as being device-related for the purposes of this analysis. Nonetheless, the data still demonstrated a reduction in re-hospitalization related hospital days and significant cost savings for the HeartMate 3 compared to the HeartMate II.


Story Source:

Materials provided by Brigham and Women's Hospital. Note: Content may be edited for style and length.


Journal Reference:

  1. Mandeep R. Mehra, Christopher Salerno, Joseph C. Cleveland, Sean Pinney, Melana Yuzefpolskaya, Carmelo A. Milano, Akinobu Itoh, Daniel J. Goldstein, Nir Uriel, Sanjeev Gulati, Francis D. Pagani, Ranjit John, Robert M. Adamson, Roberta C. Bogaev, Vinay Thohan, Joyce Chuang, Poornima Sood, Scott Goates, Scott C. Silvestry. Health Care Resource Use and Cost Implications in the MOMENTUM 3 Long-Term Outcome Study: A Randomized Controlled Trial of a Magnetically Levitated Cardiac Pump in Advanced Heart Failure. Circulation, 2018; CIRCULATIONAHA.118.035722 DOI: 10.1161/CIRCULATIONAHA.118.035722

Cite This Page:

Brigham and Women's Hospital. "New cardiac pump device more effective, less costly than standard pump." ScienceDaily. ScienceDaily, 4 June 2018. <www.sciencedaily.com/releases/2018/06/180604155448.htm>.
Brigham and Women's Hospital. (2018, June 4). New cardiac pump device more effective, less costly than standard pump. ScienceDaily. Retrieved February 27, 2024 from www.sciencedaily.com/releases/2018/06/180604155448.htm
Brigham and Women's Hospital. "New cardiac pump device more effective, less costly than standard pump." ScienceDaily. www.sciencedaily.com/releases/2018/06/180604155448.htm (accessed February 27, 2024).

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