New! Sign up for our free email newsletter.
Reference Terms
from Wikipedia, the free encyclopedia

Heart

The heart is a muscular organ that serves as the central pump of the circulatory system, responsible for delivering oxygenated blood to the body and returning deoxygenated blood to the lungs. Roughly the size of a fist, the heart is located slightly left of center in the chest, protected by the ribcage and enclosed in a fluid-filled sac called the pericardium. Its continuous, rhythmic contractions ensure that blood circulates efficiently through a vast network of arteries, veins, and capillaries, sustaining every organ and tissue.

The heart is divided into four chambers: two upper atria and two lower ventricles. Blood flows through the heart in a coordinated sequence controlled by one-way valves that prevent backflow. The right side of the heart receives oxygen-poor blood from the body and pumps it to the lungs, while the left side receives oxygen-rich blood from the lungs and sends it out to the rest of the body. This dual-pump system, known as the pulmonary and systemic circuits, operates under the control of electrical impulses generated by the heart’s internal conduction system.

The heartbeat is regulated by the sinoatrial (SA) node, often called the natural pacemaker, which initiates electrical signals that spread through the heart muscle, prompting it to contract. These signals maintain a regular rhythm, adjusting in response to physical activity, stress, or other physiological demands. The autonomic nervous system and various hormones also influence heart rate and force of contraction, enabling the heart to respond dynamically to the body’s needs.

Heart health is critical for overall well-being. Conditions such as coronary artery disease, heart failure, arrhythmias, and hypertension can impair its function and lead to life-threatening complications. Lifestyle factors like diet, exercise, and stress management play a major role in maintaining cardiovascular health, while advances in medicine continue to improve diagnosis, treatment, and prevention of heart disease. The heart’s efficiency and resilience make it one of the most remarkable organs in the human body.

Related Stories
 


Health & Medicine News

November 25, 2025

Scientists discovered that more muscle and less hidden abdominal fat are linked to a younger biological brain age. Deep visceral fat appeared to accelerate brain aging, while muscle mass offered a protective ...
Scientists have found that a mutation tied to Alzheimer’s disrupts the production and quality of exosomes—tiny cell-made communication packets. Cells with the defective SORLA protein generate fewer exosomes and ones far less able to support ...
Ribosomes don’t just make proteins—they can sense when something’s wrong. When they collide, they send out stress signals that activate a molecule called ZAK. Researchers uncovered how ZAK recognizes these collisions and turns them into ...
Scientists found that high-flavanol foods can prevent the decline in blood vessel function that occurs after prolonged sitting. Even physically fit men weren’t protected unless they had consumed flavanols beforehand. A cocoa drink rich in these ...
Participants lost more weight on a low-fat vegan diet than on the Mediterranean diet, largely due to eliminating animal foods and reducing oils and nuts. Increased intake of plant foods, even ...
Scientists are uncovering what makes some carcinomas so resistant: their ability to change identity. Two new studies reveal crucial proteins and structures that could become targets for future ...
Hypertension begins harming the brain surprisingly early, even before measurable blood pressure increases. Key cells related to blood vessels, signaling, and myelin maintenance begin aging prematurely and malfunctioning. These disruptions resemble ...
Scientists have uncovered how leukemia cells manage to escape one of the most commonly used treatments. Over time, these cancer cells subtly change the shape of their mitochondria to avoid dying when the drug tries to kill them. By identifying the ...
A research team has found that specific immune cells can connect with muscle fibers in a lightning-fast, neuron-like way to promote healing. These cells deliver quick pulses of calcium, triggering repair within seconds. The mechanism works in both ...
A massive long-term study shows that Mediterranean and plant-based diets can help prevent chronic constipation in aging adults. Surprisingly, the benefits weren’t explained by fiber alone. Western and inflammatory diets raised constipation risk, ...
Ultra-processed foods are rapidly becoming a global dietary staple, and new research links them to worsening health outcomes around the world. Scientists say only bold, coordinated policy action can counter corporate influence and shift food systems ...
Researchers have uncovered a surprising new role for the HSL protein: beyond breaking down fat, it also works inside the nucleus of fat cells to keep them functioning properly. When HSL is missing, fat tissue doesn’t expand as expected— instead, ...

Latest Headlines

updated 12:56 pm ET