Eating ultra-processed foods may rewire the brain and drive overeating

"Our findings suggest that higher consumption of ultra-processed foods is associated with differences in the brain. These associations could be linked to behavioral patterns such as overeating, though causal relationships cannot be confirmed by our study. The observed associations are not solely explained by inflammation or obesity; ingredients and additives typical to UPFs, such as emulsifiers may also play a role, although this requires further longitudinal or experimental evidence," explains the study's shared first author, Arsène Kanyamibwa from the University of Helsinki.

Processed vs. Ultra-Processed: Understanding the Difference

Not all processed foods are harmful. Many processed items, especially those based on plants, are beneficial parts of a balanced diet. However, ultra-processed foods -- those containing industrial additives and chemically altered ingredients -- raise significant health concerns.

"In particular, processed foods of plant origin, such as frozen vegetables, can be recommended. Another good example of the benefits of processing is the pasteurization of milk. In contrast, foods high in chemically modified ingredients and additives, such as processed meat products, are problematic."

Implications for Diet and Public Health

Kanyamibwa highlights how emerging research like this can influence both personal food choices and public health policy.

"Given the growing body of evidence, reducing ultra-processed food intake and strengthening regulatory standards in food manufacturing may be crucial steps toward ensuring better public health outcomes," Kanyamibwa asserts.

The investigation drew on data from the UK Biobank, a large-scale health database including middle-aged participants from across the United Kingdom. The research was carried out through a collaboration between the University of Helsinki and McGill University's Montréal Neurological Institute, combining expertise in nutrition, neuroscience, and imaging analysis to explore how modern diets may be influencing the human brain.