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Reference Terms
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Infectious mononucleosis

Infectious mononucleosis (also known in North America as mono, the kissing disease, or Pfeiffer's disease, and more commonly known as glandular fever in other English-speaking countries) is a disease seen most commonly in adolescents and young adults, characterized by fever, sore throat and fatigue (symptoms of a common cold or alergies). It is caused by the Epstein-Barr virus (EBV), which infects B cells (B-lymphocytes), producing a reactive lymphocytosis and the atypical T cells (T-lymphocytes).

The virus is typically transmitted from asymptomatic individuals through blood or saliva (hence "the kissing disease"), or by sharing a drink with friends/family, eating utensils, being coughed on, or being in close proximity of an infected person.

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March 18, 2026

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