Reference Terms
from Wikipedia, the free encyclopedia
Somatic cell nuclear transfer
In genetics and developmental biology, somatic cell nuclear transfer (SCNT) is a laboratory technique for creating an ovum with a donor nucleus. It can be used in embryonic stem cell research, or in regenerative medicine where it is sometimes referred to as "therapeutic cloning." It can also be used as the first step in the process of reproductive cloning. In SCNT the nucleus, which contains the organism's DNA, of a somatic cell (a body cell other than a sperm or egg cell) is removed and the rest of the cell discarded. At the same time, the nucleus of an egg cell is removed. The nucleus of the somatic cell is then inserted into the enucleated egg cell. After being inserted into the egg, the somatic cell nucleus is reprogrammed by the host cell. The egg, now containing the nucleus of a somatic cell, is stimulated with a shock and will begin to divide. After many mitotic divisions in culture, this single cell forms a blastocyst (an early stage embryo with about 100 cells) with almost identical DNA to the original organism.
Related Stories
1
2
Health & Medicine News
June 22, 2026
June 22, 2026 A clinical trial is exploring whether high doses of vitamin B3 could give patients with glioblastoma a better chance against the aggressive brain cancer. Scientists found that niacin may help revive immune cells that tumors shut down, allowing them ...
June 22, 2026 Scientists discovered that Heliconius butterflies have evolved an extraordinary lifespan, living several times longer than closely related species. Even more surprising, some show little sign of physical decline as they age. Their unusual ...
June 22, 2026 Two dangerous viruses are back in the spotlight, reminding health officials how quickly infectious diseases can become serious threats. Hantavirus, often linked to rodents, can cause severe heart and lung complications and has no specific treatment ...
June 21, 2026 Not all fats affect your body the same way. Researchers found that palmitic acid, a saturated fat common in many foods, may contribute to insulin resistance and type 2 diabetes by triggering inflammation, toxic fat buildup, and cellular stress. In ...
June 21, 2026 A study of long-lived families has identified rare genetic variants that may help people stay healthier for much longer as they age. One standout mutation appears to temper inflammation, potentially delaying disease and extending years of healthy ...
June 21, 2026 Scientists at Baylor College of Medicine may have uncovered a promising new way to combat Alzheimer’s and Parkinson’s disease. Instead of trying to stop Tau and alpha-synuclein proteins from ...
June 21, 2026 A long-term Yale study is challenging one of the biggest myths about aging. Nearly half of adults over 65 improved physically, mentally, or both over time, despite the common belief that aging means constant decline. Researchers found that people ...
June 21, 2026 As newborn neurons make their way through the developing brain, they must squeeze through incredibly tight spaces to reach their final destinations. Researchers discovered that this physical journey routinely causes some of the most severe forms of ...
June 21, 2026 Researchers have concluded that nicotine vapes are likely to cause lung and oral cancers, based on evidence ranging from human biomarkers to animal and laboratory studies. The findings challenge the idea that vaping is a harmless alternative to ...
June 20, 2026 Scientists have discovered that a gene normally considered a DNA-protecting "good guy" can become dangerous when cells make too much of it. The gene, EXO1, acts like molecular scissors that help repair DNA, but when overproduced it starts cutting ...
June 20, 2026 The obesity treatment landscape is changing fast, with GLP-1 drugs opening the door to more effective care than ever before. Experts now envision a future where medications, minimally invasive ...
June 19, 2026 Eating five servings of fruits and vegetables may not be enough if you're missing foods rich in flavanols, a group of compounds linked to better heart health. Researchers found that choices like ...
Latest Headlines
updated 12:56 pm ET
June 19, 2026 A newly identified molecule called OLE helped restore the brain’s immune cells to a more protective state in Alzheimer’s models. The treatment reduced toxic plaque buildup and improved memory, ...
June 19, 2026 A new biomaterial made from jackfruit latex, pomegranate peel, and simvastatin could transform the treatment of severe gum disease. Early tests suggest it not only combats infection and inflammation ...
June 18, 2026 Scientists may have uncovered a hidden trigger behind Alzheimer’s disease. Instead of plaques being the root cause, amyloid beta appears to interfere with tau, a protein that helps keep neurons ...
June 18, 2026 Plague was already a deadly killer 5,500 years ago, long before cities, farming, or the rat-infested conditions usually linked to historic outbreaks. By analyzing ancient DNA from hunter-gatherer ...
June 18, 2026 Scientists at Mayo Clinic have uncovered a surprising new way the kidneys conserve water, revealing a hidden backup system that works independently of the hormone long believed to control the ...
June 18, 2026 A major study of more than 112,000 people found that eating foods containing common preservatives may be linked to a higher risk of high blood ...
June 17, 2026 Scientists have taken a surprising step toward unlocking regeneration in mammals, showing that the ability to rebuild complex body parts may not be lost after all—it may simply be switched off. ...
June 17, 2026 A Rutgers study suggests GLP-1 drugs such as Ozempic and Wegovy may weaken the link between impulsive tendencies and violent behavior. The surprising finding hints that these medications could affect ...
June 17, 2026 Exposure to a common plastic chemical before and shortly after birth may have lasting effects on behavior. Researchers found that male rats exposed early in life to DEHP—a plasticizer used in ...
June 17, 2026 A small clinical trial suggests that probiotics may offer a surprising mental health boost for older adults with depression. Seniors who took a daily probiotic alongside their regular antidepressant ...