Reference Terms
from Wikipedia, the free encyclopedia
Somatic cell nuclear transfer
In genetics and developmental biology, somatic cell nuclear transfer (SCNT) is a laboratory technique for creating an ovum with a donor nucleus. It can be used in embryonic stem cell research, or in regenerative medicine where it is sometimes referred to as "therapeutic cloning." It can also be used as the first step in the process of reproductive cloning. In SCNT the nucleus, which contains the organism's DNA, of a somatic cell (a body cell other than a sperm or egg cell) is removed and the rest of the cell discarded. At the same time, the nucleus of an egg cell is removed. The nucleus of the somatic cell is then inserted into the enucleated egg cell. After being inserted into the egg, the somatic cell nucleus is reprogrammed by the host cell. The egg, now containing the nucleus of a somatic cell, is stimulated with a shock and will begin to divide. After many mitotic divisions in culture, this single cell forms a blastocyst (an early stage embryo with about 100 cells) with almost identical DNA to the original organism.
Related Stories
1
2
Health & Medicine News
July 5, 2026
July 5, 2026 Researchers have identified the brain circuitry that links deep sleep with the release of growth hormone, revealing how the two regulate each other. The newly discovered feedback loop helps explain ...
July 5, 2026 Some cancer cells evade treatment by entering a dormant state triggered by stress hormones. ETH Zurich scientists have created a light-controlled molecular switch that selectively destroys the receptors responsible for this survival mode. In ...
July 4, 2026 Some people live past 100 with remarkable health, and researchers may have uncovered one reason why. A new study found that centenarians have a unique chemical "fingerprint" in their blood that sets them apart from normal aging, including unusual ...
July 4, 2026 A UCLA study has identified a hidden Achilles' heel in aggressive small cell cancers that have resisted new treatments for decades. Scientists found that tumors lacking the RB gene become critically dependent on the protein E2F3 for survival. ...
July 4, 2026 A new intranasal DNA vaccine may give the immune system an extra weapon against tuberculosis by targeting bacteria that can hide from antibiotics. In animal studies, it helped clear infections faster, reduced lung inflammation, and prevented relapse ...
July 3, 2026 Using alcohol to cope with stress when young may permanently alter the brain, making it harder to adapt to challenges and increasing the risk of returning to drinking later in life. Researchers also found signs of brain damage associated with early ...
July 3, 2026 Some brains appear to fight back against Alzheimer's by helping immature brain cells survive damage instead of succumbing to it. Understanding this natural resilience could point researchers toward entirely new ways to protect memory and slow ...
July 3, 2026 Scientists at UCLA discovered a surprising reason aging muscles heal more slowly. In older muscle stem cells, a protein called NDRG1 builds up and acts like a brake, slowing the cells’ ability to jump into repair mode after injury. But there’s a ...
July 3, 2026 Scientists have discovered that a common type of stroke may have a very different cause than doctors once thought. Instead of fatty plaque clogging arteries, the strongest link was found with enlarged and damaged blood vessels deep within the brain. ...
July 2, 2026 A protein called “Mitch” may hold the key to a new generation of obesity treatments. Researchers found that disabling it in human cells boosts fat burning, increases energy use, and makes it ...
July 2, 2026 A new spray-on powder developed by KAIST can stop life-threatening bleeding in about one second by instantly forming a strong gel over a wound. It works on deep and irregular injuries where conventional hemostatic products often struggle and remains ...
July 2, 2026 Scientists at the University of Oxford have created a calculator that predicts a person's individual risk of serious muscle disorders from statin medications. Their analysis found that more than 98% ...
Latest Headlines
updated 12:56 pm ET
July 1, 2026 A massive national study found that nearly half of Americans with kidney failure who are referred for a transplant never even begin the evaluation process, and only 19% make it onto the transplant ...
July 1, 2026 A surprising discovery is overturning a long-held assumption about how the brain’s movement center works. Researchers found that two key cerebellar ...
July 1, 2026 What if Sigmund Freud was onto something that modern neuroscience is only now beginning to explain? A new paper argues that today's leading theory of the brain—as a prediction machine constantly ...
July 1, 2026 Could something as simple as vitamin C help support a healthier aging brain? In a study of more than 2,000 older adults in Japan, researchers found that people with lower vitamin C levels in their ...
June 30, 2026 Researchers have uncovered an unexpected antiviral defense system in sea anemones that works very differently from the one humans use. The discovery suggests evolution developed multiple ways to ...
June 30, 2026 A Colorado research team has created experimental osteoarthritis treatments that appear to regenerate damaged joints rather than just relieve pain. In animal studies, a single injection restored ...
June 30, 2026 A common brain protein may be giving Alzheimer’s disease an unexpected way to spread, carrying toxic Tau proteins from damaged neurons into healthy ones. By blocking these harmful protein packages ...
June 30, 2026 Creatine is best known as a muscle-building supplement, but scientists are now investigating whether it could also help treat depression by boosting the brain's energy supply. A new review examined ...
June 29, 2026 A new stem-cell-inspired technique allows scientists to grow vast numbers of immune-cell progenitors that can be engineered to hunt cancer and ...
June 29, 2026 Researchers tested experimental PCAI compounds against pancreatic cancer cells and found they had powerful anticancer effects. One leading compound ...