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NIH Researchers Find First Parkinson's Disease Gene

Date:
June 29, 1997
Source:
National Human Genome Research Institute
Summary:
Scientists at the National Human Genome Research Institute (NHGRI) at the National Institutes of Health (NIH) have for the first time precisely identified a gene abnormality that causes some cases of Parkinson's disease.

Bethesda, MD -- Scientists at the National Human Genome Research Institute (NHGRI) at the National Institutes of Health (NIH) have for the first time precisely identified a gene abnormality that causes some cases of Parkinson's disease. The gene spells out instructions for a protein called alpha synuclein. In the abnormal version of the gene, the researchers found a mutation in a single base pair-one incorrect letter in the string of more than 400 that compose the instructions for making the protein. Because the normal gene plays a role in the function of nerve cells, the finding gives researchers a powerful new tool for understanding cellular abnormalities in Parkinson's disease and demonstrates a connection between Parkinson's disease research and research into other neurological disorders, such as Alzheimer's disease.


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The above story is based on materials provided by National Human Genome Research Institute. Note: Materials may be edited for content and length.


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National Human Genome Research Institute. "NIH Researchers Find First Parkinson's Disease Gene." ScienceDaily. ScienceDaily, 29 June 1997. <www.sciencedaily.com/releases/1997/06/970629235820.htm>.
National Human Genome Research Institute. (1997, June 29). NIH Researchers Find First Parkinson's Disease Gene. ScienceDaily. Retrieved April 21, 2014 from www.sciencedaily.com/releases/1997/06/970629235820.htm
National Human Genome Research Institute. "NIH Researchers Find First Parkinson's Disease Gene." ScienceDaily. www.sciencedaily.com/releases/1997/06/970629235820.htm (accessed April 21, 2014).

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