Featured Research

from universities, journals, and other organizations

Lack Of Exercise, High Intakes Of Sugar And Saturated Fat: A Recipe For Gallstones, UB Study Shows

Date:
February 24, 1999
Source:
University At Buffalo
Summary:
The Western lifestyle of little exercise, lots of saturated fat, loads of refined sugar and little fiber is a major risk factor for the development of yet another chronic medical condition -- gallstones -- a new University at Buffalo study shows.

BUFFALO, N.Y. -- The Western lifestyle of little exercise, lots of saturated fat, loads of refined sugar and little fiber is a major risk factor for the development of yet another chronic medical condition -- gallstones -- a new University at Buffalo study shows.

Published in the February issue of the American Journal of Clinical Nutrition, the study is one of the few population-based investigations of factors affecting the development of gallbladder disease over time.

Results showed that body mass index and intake of refined sugar and saturated fat were directly associated with the formation of gallstones. The relationship between saturated fat and gallstones was stronger in men than in women.

Conversely, physical activity and a diet high in monounsaturated fat and insoluble dietary fiber were protective against gallstones, results showed.

"This study confirms that gallbladder disease is one of the diseases of Western civilization," said epidemiologist Maurizio Trevisan, chair of the UB Department of Social and Preventive Medicine and author of the study.

"It is one more message that a diet high in fat and refined sugar and a pattern of low physical activity can get you into all kinds of trouble."

The results are interesting to epidemiologists, he said, because they support the hypothesis that common pathophysiological mechanisms may underlie the chronic diseases afflicting Western populations. Gallbladder disease is increasingly common with age, and affects more women than men. Twenty percent of women are reported to have gallstones at autopsy.

The study was conducted in the small farming community of Castellana in southern Italy. In 1985 and 1986, researchers administered ultrasound scans of the gallbladder and took blood

samples from 1,429 men and 1,043 women selected randomly from the population. Persons free of gallstones at that time were re-examined by ultrasound between May 1992 and June 1993, and completed questionnaires concerning sociodemographic status, medical history, dietary habits and physical activity.

The 55 men and 49 women who had developed gallstones during the study period then were matched with controls from the study population. These participants provided information on how often they ate certain foods to give a more complete picture of dietary intake.

Analysis of the data from new cases and controls showed that age, body mass index (an indication of obesity) and prevalence of diabetes were higher, while physical activity was lower, in those who developed gallstones than in those who did not. Dieting, caffeine and smoking appeared to have little effect.

Dietary analysis showed that higher intake of monounsaturated fats and higher expenditure of calories lowered the risk of gallstones, while higher consumption of refined sugars and saturated fat were directly related to gallstone formation.

Particularly interesting was the finding that saturated-fat intake appears to have a stronger relationship to gallstone formation in men than women, Trevisan said. Women had higher rates of gallstones at the first three quartiles of saturated fat consumption, but their risk increased slowly as consumption increased. However, the risk doubled for men at each quartile of consumption and at the highest quartile, men were at a higher risk of developing gallstones than women.

"These findings seem to suggest that other factors, such as hormones or metabolism, may be more powerful risk factors for gallstone formation among women than saturated fat intake," Trevisan said.

The research team was headed by Giovanni Misciagna, M.D., chief of the laboratory of epidemiology and biostatistics at the Institute S. De Bellis, a gastroenterology clinical research center in Castellana.


Story Source:

The above story is based on materials provided by University At Buffalo. Note: Materials may be edited for content and length.


Cite This Page:

University At Buffalo. "Lack Of Exercise, High Intakes Of Sugar And Saturated Fat: A Recipe For Gallstones, UB Study Shows." ScienceDaily. ScienceDaily, 24 February 1999. <www.sciencedaily.com/releases/1999/02/990224072505.htm>.
University At Buffalo. (1999, February 24). Lack Of Exercise, High Intakes Of Sugar And Saturated Fat: A Recipe For Gallstones, UB Study Shows. ScienceDaily. Retrieved July 29, 2014 from www.sciencedaily.com/releases/1999/02/990224072505.htm
University At Buffalo. "Lack Of Exercise, High Intakes Of Sugar And Saturated Fat: A Recipe For Gallstones, UB Study Shows." ScienceDaily. www.sciencedaily.com/releases/1999/02/990224072505.htm (accessed July 29, 2014).

Share This




More Health & Medicine News

Tuesday, July 29, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Deadly Ebola Virus Threatens West Africa

Deadly Ebola Virus Threatens West Africa

AP (July 28, 2014) West African nations and international health organizations are working to contain the largest Ebola outbreak in history. It's one of the deadliest diseases known to man, but the CDC says it's unlikely to spread in the U.S. (July 28) Video provided by AP
Powered by NewsLook.com
$15B Deal on Vets' Health Care Reached

$15B Deal on Vets' Health Care Reached

AP (July 28, 2014) A bipartisan deal to improve veterans health care would authorize at least $15 billion in emergency spending to fix a veterans program scandalized by long patient wait times and falsified records. (July 28) Video provided by AP
Powered by NewsLook.com
Two Americans Contract Ebola in Liberia

Two Americans Contract Ebola in Liberia

Reuters - US Online Video (July 28, 2014) Two American aid workers in Liberia test positive for Ebola while working to combat the deadliest outbreak of the virus ever. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Traditional African Dishes Teach Healthy Eating

Traditional African Dishes Teach Healthy Eating

AP (July 28, 2014) Classes are being offered nationwide to encourage African Americans to learn about cooking fresh foods based on traditional African cuisine. The program is trying to combat obesity, heart disease and other ailments often linked to diet. (July 28) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins