Scientists have achieved a major step toward finding a new class of oral drugs to treat HIV infection. They have identified a class of compounds that prevent HIV infection by stopping the virus at its port of entry into the cell. Unlike currently used drugs that target HIV at other points during its life cycle--after it has already infected the cell--these compounds lock into a vulnerable "pocket" in the HIV's coat protein, preventing its fusion with cell membranes and thereby its ability to enter and infect cells.
The above story is based on materials provided by Whitehead Institute For Biomedical Research. Note: Materials may be edited for content and length.
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