Featured Research

from universities, journals, and other organizations

Patient At Cedars-Sinai Medical Center Becomes First In California To Have “Bad” Cholesterol Removed From Blood Through Innovative Procedure

Date:
February 11, 2000
Source:
Cedars-Sinai Medical Center
Summary:
A teen-ager at Cedars-Sinai Medical Center recently became the first in California to have their “bad” cholesterol level dramatically reduced through LDL apheresis, a procedure that has been developed for patients who have dangerously high levels of LDL cholesterol that do not respond to diet and drug treatment. This patient was born with a genetic defect that had caused very high levels of LDL since birth, and at this young age, had already undergone two heart surgeries to clean out and bypass some of the major blood vessels in and around the heart.

LOS ANGELES (February 10, 2000) – A teen-ager at Cedars-Sinai Medical Center recently became the first in the state to have their “bad” cholesterol level dramatically reduced through LDL apheresis. The patient was born with a genetic defect that had caused very high levels of LDL since birth, and at this young age, had already undergone two heart surgeries to clean out and bypass some of the major blood vessels in and around the heart.

Related Articles


Cedars-Sinai Medical Center is the first site in California to offer the procedure that has been developed for patients who have dangerously high levels of LDL cholesterol that do not respond to diet and drug treatment. Patients who need this therapy have genetic abnormalities that cause their “bad” cholesterol (also called LDL cholesterol) to be many times that of normal patients. Some of these patients develop heart disease so early that they may have a heart attack or need heart surgery before the age of 10.

After years of testing in the United States and other countries, LDL apheresis has been found to dramatically reduce levels of LDL – the type of cholesterol that increases the risk of heart disease.

“The concept has existed for 20 years or so but it has become more effective and popular now because of computers and miniaturization,” said Timothy A. Denton, M.D., an attending cardiologist at Cedars-Sinai and Medical Director of the LDL-Apheresis Program. “With this procedure we can reduce LDL levels very effectively.”

During treatment, blood is continuously removed from a patient’s vein and passed through a machine that separates red blood cells from plasma. The blood cells are returned immediately to the bloodstream through a different vein while the plasma enters a column that captures most of the LDL. The plasma is then returned to the patient without the “bad” cholesterol but with the “good” cholesterol and other vital chemicals intact.

“The procedure takes about two to four hours and must be repeated every one to three weeks, depending on the LDL level”, says Dennis Goldfinger, M.D., Director of the Cedars-Sinai Transfusion Center, where the procedure is performed.

For most people, LDL cholesterol levels can be controlled through a combination of diet, exercise and drugs. This procedure is considered a potentially life-saving last resort for people whose LDL level remains very high despite taking at least two cholesterol-lowering drugs.

“With the addition of LDL apheresis, Cedars-Sinai now can provide complete therapy for every patient with hypercholesterolemia,” said P.K. Shah, M.D., Director of Cardiology at Cedars-Sinai. “If a patient does not have success with diet and drugs, they could be a candidate for this unique treatment.”

To determine whether LDL apheresis may be helpful and appropriate, a formal screening process is in place to review medical records and perform physical assessments of potential candidates.

Anyone interested may contact the LDL apheresis program directly at 1-800-432-7831, or can be referred by their physician.

# # #

For media information and to arrange an interview, please call 1-800-396-1002. Thanks for not publishing this number in stories.


Story Source:

The above story is based on materials provided by Cedars-Sinai Medical Center. Note: Materials may be edited for content and length.


Cite This Page:

Cedars-Sinai Medical Center. "Patient At Cedars-Sinai Medical Center Becomes First In California To Have “Bad” Cholesterol Removed From Blood Through Innovative Procedure." ScienceDaily. ScienceDaily, 11 February 2000. <www.sciencedaily.com/releases/2000/02/000210233356.htm>.
Cedars-Sinai Medical Center. (2000, February 11). Patient At Cedars-Sinai Medical Center Becomes First In California To Have “Bad” Cholesterol Removed From Blood Through Innovative Procedure. ScienceDaily. Retrieved November 21, 2014 from www.sciencedaily.com/releases/2000/02/000210233356.htm
Cedars-Sinai Medical Center. "Patient At Cedars-Sinai Medical Center Becomes First In California To Have “Bad” Cholesterol Removed From Blood Through Innovative Procedure." ScienceDaily. www.sciencedaily.com/releases/2000/02/000210233356.htm (accessed November 21, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, November 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Milestone Birthdays Can Bring Existential Crisis, Study Says

Milestone Birthdays Can Bring Existential Crisis, Study Says

Newsy (Nov. 21, 2014) Researchers find that as people approach new decades in their lives they make bigger life decisions. Video provided by Newsy
Powered by NewsLook.com
Ebola: Life Without School in Guinea

Ebola: Life Without School in Guinea

AFP (Nov. 21, 2014) Following the closure of schools and universities in Guinea because of the Ebola virus, students look for temporary work or gather in makeshift classrooms to catch up on their syllabus. Duration: 02:14 Video provided by AFP
Powered by NewsLook.com
UN Says It Will Scale Up Its Ebola Response

UN Says It Will Scale Up Its Ebola Response

AFP (Nov. 20, 2014) UN Resident Coordinator David McLachlan-Karr and WHO representative in the country Daniel Kertesz updated the media on the UN Ebola response on Wednesday. Duration: 00:51 Video provided by AFP
Powered by NewsLook.com
Takata Offers "sincerest Condolences" To Victims of Malfunctioning Airbag

Takata Offers "sincerest Condolences" To Victims of Malfunctioning Airbag

Reuters - US Online Video (Nov. 20, 2014) U.S. Congress hears from a victim and company officials as it holds a hearing on the safety of Takata airbags after reports of injuries. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins