Featured Research

from universities, journals, and other organizations

Patient At Cedars-Sinai Medical Center Becomes First In California To Have “Bad” Cholesterol Removed From Blood Through Innovative Procedure

Date:
February 11, 2000
Source:
Cedars-Sinai Medical Center
Summary:
A teen-ager at Cedars-Sinai Medical Center recently became the first in California to have their “bad” cholesterol level dramatically reduced through LDL apheresis, a procedure that has been developed for patients who have dangerously high levels of LDL cholesterol that do not respond to diet and drug treatment. This patient was born with a genetic defect that had caused very high levels of LDL since birth, and at this young age, had already undergone two heart surgeries to clean out and bypass some of the major blood vessels in and around the heart.

LOS ANGELES (February 10, 2000) – A teen-ager at Cedars-Sinai Medical Center recently became the first in the state to have their “bad” cholesterol level dramatically reduced through LDL apheresis. The patient was born with a genetic defect that had caused very high levels of LDL since birth, and at this young age, had already undergone two heart surgeries to clean out and bypass some of the major blood vessels in and around the heart.

Cedars-Sinai Medical Center is the first site in California to offer the procedure that has been developed for patients who have dangerously high levels of LDL cholesterol that do not respond to diet and drug treatment. Patients who need this therapy have genetic abnormalities that cause their “bad” cholesterol (also called LDL cholesterol) to be many times that of normal patients. Some of these patients develop heart disease so early that they may have a heart attack or need heart surgery before the age of 10.

After years of testing in the United States and other countries, LDL apheresis has been found to dramatically reduce levels of LDL – the type of cholesterol that increases the risk of heart disease.

“The concept has existed for 20 years or so but it has become more effective and popular now because of computers and miniaturization,” said Timothy A. Denton, M.D., an attending cardiologist at Cedars-Sinai and Medical Director of the LDL-Apheresis Program. “With this procedure we can reduce LDL levels very effectively.”

During treatment, blood is continuously removed from a patient’s vein and passed through a machine that separates red blood cells from plasma. The blood cells are returned immediately to the bloodstream through a different vein while the plasma enters a column that captures most of the LDL. The plasma is then returned to the patient without the “bad” cholesterol but with the “good” cholesterol and other vital chemicals intact.

“The procedure takes about two to four hours and must be repeated every one to three weeks, depending on the LDL level”, says Dennis Goldfinger, M.D., Director of the Cedars-Sinai Transfusion Center, where the procedure is performed.

For most people, LDL cholesterol levels can be controlled through a combination of diet, exercise and drugs. This procedure is considered a potentially life-saving last resort for people whose LDL level remains very high despite taking at least two cholesterol-lowering drugs.

“With the addition of LDL apheresis, Cedars-Sinai now can provide complete therapy for every patient with hypercholesterolemia,” said P.K. Shah, M.D., Director of Cardiology at Cedars-Sinai. “If a patient does not have success with diet and drugs, they could be a candidate for this unique treatment.”

To determine whether LDL apheresis may be helpful and appropriate, a formal screening process is in place to review medical records and perform physical assessments of potential candidates.

Anyone interested may contact the LDL apheresis program directly at 1-800-432-7831, or can be referred by their physician.

# # #

For media information and to arrange an interview, please call 1-800-396-1002. Thanks for not publishing this number in stories.


Story Source:

The above story is based on materials provided by Cedars-Sinai Medical Center. Note: Materials may be edited for content and length.


Cite This Page:

Cedars-Sinai Medical Center. "Patient At Cedars-Sinai Medical Center Becomes First In California To Have “Bad” Cholesterol Removed From Blood Through Innovative Procedure." ScienceDaily. ScienceDaily, 11 February 2000. <www.sciencedaily.com/releases/2000/02/000210233356.htm>.
Cedars-Sinai Medical Center. (2000, February 11). Patient At Cedars-Sinai Medical Center Becomes First In California To Have “Bad” Cholesterol Removed From Blood Through Innovative Procedure. ScienceDaily. Retrieved September 23, 2014 from www.sciencedaily.com/releases/2000/02/000210233356.htm
Cedars-Sinai Medical Center. "Patient At Cedars-Sinai Medical Center Becomes First In California To Have “Bad” Cholesterol Removed From Blood Through Innovative Procedure." ScienceDaily. www.sciencedaily.com/releases/2000/02/000210233356.htm (accessed September 23, 2014).

Share This



More Health & Medicine News

Tuesday, September 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Costs Keep Mounting

Ebola Costs Keep Mounting

Reuters - Business Video Online (Sep. 23, 2014) The WHO has warned up to 20,000 people could be infected with Ebola over the next few weeks. As Sonia Legg reports, the implications for the West African countries suffering from the disease are huge. Video provided by Reuters
Powered by NewsLook.com
Liberia Pleads for Help to Fight Ebola

Liberia Pleads for Help to Fight Ebola

AP (Sep. 22, 2014) Liberia's finance minister is urging the international community to quickly follow through on pledges of cash to battle Ebola. Bodies are piling up in the capital Monrovia as the nation awaits more help. (Sept. 22) Video provided by AP
Powered by NewsLook.com
Ebola Doctor Says Border Controls Critical

Ebola Doctor Says Border Controls Critical

AP (Sep. 22, 2014) A Florida doctor who helped fight the expanding Ebola outbreak in West Africa says the disease can be stopped, but only if nations quickly step up their response and make border control a priority. (Sept. 22) Video provided by AP
Powered by NewsLook.com
Global Ebola Aid Increasing But Critics Say It's Late

Global Ebola Aid Increasing But Critics Say It's Late

Newsy (Sep. 21, 2014) More than 100 tons of medical supplies were sent to West Africa on Saturday, but aid workers say the global response is still sluggish. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins