Featured Research

from universities, journals, and other organizations

Vision-Saving Treatment Effective For Patients With Eye Cancer

Date:
July 17, 2001
Source:
Ohio State University
Summary:
Patients suffering from a certain form of cancer of the eye may not need to have their diseased eye removed, based on a new study.

COLUMBUS, Ohio - Patients suffering from a certain form of cancer of the eye may not need to have their diseased eye removed, based on a new study.

Related Articles


The results of the Collaborative Ocular Melanoma Study (COMS), a multi-center trial released today (July 12) by the Archives of Ophthalmology, found that survival rates were the same regardless of whether the eye was removed or the patient had instead undergone radiation therapy. Ohio State University is one of more than 40 centers throughout the United States and Canada participating in the study.

Traditionally, physicians have removed the affected eye in patients with this disease, said Frederick Davidorf, a professor of ophthalmology at Ohio State and a principal investigator with the COMS.

The study looked at 1,317 patients with choroidal melanoma -- or cancer of the choroid, the thin layer of vessels beneath the retina. The choroid contains most of the eye's melanocytes, cells that produce and contain pigment. The patients all had medium-sized tumors (2.5 to 10 mm in height and no more than 16 mm in diameter) - ranging from the size of a small pea to a lima bean. Removal of the eye is still the only option for patients with larger tumors, Davidorf said.

Half of the patients (657) underwent radiation therapy, while the other half (660) had their affected eye removed. Findings show that 82 percent of the former group and 81 percent of the latter group were living five years after initial treatment. Also, there was no evidence that either treatment caused harm to the unaffected eye, Davidorf said.

"This is a better-than-expected survival rate, based on information from previous studies of fewer patients," Davidorf said. "We had only expected a 70 percent five-year survival rate when we began the study 16 years ago."

Of the patients who underwent radiation therapy, 63 percent had visual acuity of 20/200 or worse in the treated eye. By five years after treatment, 12 percent had had the treated eye removed due to complications of the radiation treatment or tumor growth. The Ohio State researchers will continue to follow each patient for at least 15 years from initial treatment.

According to the National Eye Institute, between 1,600 and 2,400 new cases of ocular melanoma are diagnosed each year in the United States and Canada.

For more than a century, removal of the eye was the standard treatment for choroidal melanoma, regardless of tumor size.

"The results of this study will save many future patients the physical and mental trauma associated with the loss of an eye," Davidorf said.

Ohio State researchers began looking at radiation as an alternate therapy for choroidal melanoma as early as the late 1960s. A study co-authored by Davidorf in the January 1970 Archives of Ophthalmology found that four out of five patients with choroidal melanoma were successfully treated with radiation.

Eye care professionals typically detect melanoma by dilating a patient's pupil.

The COMS was funded by the National Eye Institute and the National Cancer Institute, which are both part of the National Institutes of Health.


Story Source:

The above story is based on materials provided by Ohio State University. Note: Materials may be edited for content and length.


Cite This Page:

Ohio State University. "Vision-Saving Treatment Effective For Patients With Eye Cancer." ScienceDaily. ScienceDaily, 17 July 2001. <www.sciencedaily.com/releases/2001/07/010717080358.htm>.
Ohio State University. (2001, July 17). Vision-Saving Treatment Effective For Patients With Eye Cancer. ScienceDaily. Retrieved December 22, 2014 from www.sciencedaily.com/releases/2001/07/010717080358.htm
Ohio State University. "Vision-Saving Treatment Effective For Patients With Eye Cancer." ScienceDaily. www.sciencedaily.com/releases/2001/07/010717080358.htm (accessed December 22, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, December 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Christmas Kissing Good for Health

Christmas Kissing Good for Health

Reuters - Innovations Video Online (Dec. 22, 2014) Scientists in Amsterdam say couples transfer tens of millions of microbes when they kiss, encouraging healthy exposure to bacteria. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Brain-Dwelling Tapeworm Reveals Genetic Secrets

Brain-Dwelling Tapeworm Reveals Genetic Secrets

Reuters - Innovations Video Online (Dec. 22, 2014) Cambridge scientists have unravelled the genetic code of a rare tapeworm that lived inside a patient's brain for at least four year. Researchers hope it will present new opportunities to diagnose and treat this invasive parasite. Matthew Stock reports. Video provided by Reuters
Powered by NewsLook.com
Touch-Free Smart Phone Empowers Mobility-Impaired

Touch-Free Smart Phone Empowers Mobility-Impaired

Reuters - Innovations Video Online (Dec. 21, 2014) A touch-free phone developed in Israel enables the mobility-impaired to operate smart phones with just a movement of the head. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Earthworms Provide Cancer-Fighting Bacteria

Earthworms Provide Cancer-Fighting Bacteria

Reuters - Innovations Video Online (Dec. 21, 2014) Polish scientists isolate bacteria from earthworm intestines which they say may be used in antibiotics and cancer treatments. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins