Featured Research

from universities, journals, and other organizations

Vision-Saving Treatment Effective For Patients With Eye Cancer

Date:
July 17, 2001
Source:
Ohio State University
Summary:
Patients suffering from a certain form of cancer of the eye may not need to have their diseased eye removed, based on a new study.

COLUMBUS, Ohio - Patients suffering from a certain form of cancer of the eye may not need to have their diseased eye removed, based on a new study.

The results of the Collaborative Ocular Melanoma Study (COMS), a multi-center trial released today (July 12) by the Archives of Ophthalmology, found that survival rates were the same regardless of whether the eye was removed or the patient had instead undergone radiation therapy. Ohio State University is one of more than 40 centers throughout the United States and Canada participating in the study.

Traditionally, physicians have removed the affected eye in patients with this disease, said Frederick Davidorf, a professor of ophthalmology at Ohio State and a principal investigator with the COMS.

The study looked at 1,317 patients with choroidal melanoma -- or cancer of the choroid, the thin layer of vessels beneath the retina. The choroid contains most of the eye's melanocytes, cells that produce and contain pigment. The patients all had medium-sized tumors (2.5 to 10 mm in height and no more than 16 mm in diameter) - ranging from the size of a small pea to a lima bean. Removal of the eye is still the only option for patients with larger tumors, Davidorf said.

Half of the patients (657) underwent radiation therapy, while the other half (660) had their affected eye removed. Findings show that 82 percent of the former group and 81 percent of the latter group were living five years after initial treatment. Also, there was no evidence that either treatment caused harm to the unaffected eye, Davidorf said.

"This is a better-than-expected survival rate, based on information from previous studies of fewer patients," Davidorf said. "We had only expected a 70 percent five-year survival rate when we began the study 16 years ago."

Of the patients who underwent radiation therapy, 63 percent had visual acuity of 20/200 or worse in the treated eye. By five years after treatment, 12 percent had had the treated eye removed due to complications of the radiation treatment or tumor growth. The Ohio State researchers will continue to follow each patient for at least 15 years from initial treatment.

According to the National Eye Institute, between 1,600 and 2,400 new cases of ocular melanoma are diagnosed each year in the United States and Canada.

For more than a century, removal of the eye was the standard treatment for choroidal melanoma, regardless of tumor size.

"The results of this study will save many future patients the physical and mental trauma associated with the loss of an eye," Davidorf said.

Ohio State researchers began looking at radiation as an alternate therapy for choroidal melanoma as early as the late 1960s. A study co-authored by Davidorf in the January 1970 Archives of Ophthalmology found that four out of five patients with choroidal melanoma were successfully treated with radiation.

Eye care professionals typically detect melanoma by dilating a patient's pupil.

The COMS was funded by the National Eye Institute and the National Cancer Institute, which are both part of the National Institutes of Health.


Story Source:

The above story is based on materials provided by Ohio State University. Note: Materials may be edited for content and length.


Cite This Page:

Ohio State University. "Vision-Saving Treatment Effective For Patients With Eye Cancer." ScienceDaily. ScienceDaily, 17 July 2001. <www.sciencedaily.com/releases/2001/07/010717080358.htm>.
Ohio State University. (2001, July 17). Vision-Saving Treatment Effective For Patients With Eye Cancer. ScienceDaily. Retrieved September 17, 2014 from www.sciencedaily.com/releases/2001/07/010717080358.htm
Ohio State University. "Vision-Saving Treatment Effective For Patients With Eye Cancer." ScienceDaily. www.sciencedaily.com/releases/2001/07/010717080358.htm (accessed September 17, 2014).

Share This



More Health & Medicine News

Wednesday, September 17, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

President To Send 3,000 Military Personnel To Fight Ebola

President To Send 3,000 Military Personnel To Fight Ebola

Newsy (Sep. 16, 2014) President Obama is expected to send 3,000 troops to West Africa as part of the effort to contain Ebola's spread. Video provided by Newsy
Powered by NewsLook.com
Obama Orders Military Response to Ebola

Obama Orders Military Response to Ebola

AP (Sep. 16, 2014) Calling the Ebola outbreak in West Africa a potential threat to global security, President Barack Obama is ordering 3,000 U.S. military personnel to the stricken region amid worries that the outbreak is spiraling out of control. (Sept. 16) Video provided by AP
Powered by NewsLook.com
UN: 20,000 Could Be Infected With Ebola by Year End

UN: 20,000 Could Be Infected With Ebola by Year End

AFP (Sep. 16, 2014) Nearly $1.0 billion dollars is needed to fight the Ebola outbreak raging in west Africa, the United Nations say, warning that 20,000 could be infected by year end. Duration: 00:40 Video provided by AFP
Powered by NewsLook.com
Obama: Ebola Outbreak Threat to Global Security

Obama: Ebola Outbreak Threat to Global Security

AP (Sep. 16, 2014) President Obama is ordering U.S. military personnel to West Africa to deal with the Ebola outbreak, which is he calls a potential threat to global security. (Sept. 16) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

    Technology News



    Save/Print:
    Share:

    Free Subscriptions


    Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

    Get Social & Mobile


    Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

    Have Feedback?


    Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
    Mobile: iPhone Android Web
    Follow: Facebook Twitter Google+
    Subscribe: RSS Feeds Email Newsletters
    Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins