Featured Research

from universities, journals, and other organizations

Long-Term Interruption Of HIV Treatment May Be Safe In Certain Patients

Date:
July 10, 2002
Source:
Northwestern University
Summary:
Interrupting anti-HIV treatment for an extended period and then re-initiating therapy might be safe in some patients, according to a study by Northwestern University infectious disease experts.

Interrupting anti-HIV treatment for an extended period and then re-initiating therapy might be safe in some patients, according to a study by Northwestern University infectious disease experts.

Related Articles


Chad Achenbach, M.D., and co-investigators from The Feinberg School of Medicine presented data from their research today at the XIV International AIDS Conference.

In an observational study, 25 HIV-infected patients with viral suppression for at least six months while receiving highly active antiretroviral therapy (HAART) interrupted treatment for an average of nine months.

None of the patients had HIV-related infections or illnesses during the interruption. All of the patients had increases in virus levels and drops in infection-fighting CD4 cells. Patients with lower virus levels prior to treatment and stronger immune systems responded more favorably during the interruption.

When HAART was resumed in 11 of the patients, they experienced maximal viral suppression and robust increases in CD4 cell counts.

Previous studies have examined whether treatment interruption could be used as a strategy for boosting immune response to HIV or reducing resistance to the medications. The current study focused on the effects of stopping HAART for longer periods to minimize complications of the therapy.

"We were surprised that so many patients were able to remain off their therapy for so long a period," Achenbach said.

"Extended treatment interruption appears safe and, after further study, may be an important HIV treatment strategy for the reduction of long-term toxicity, medication burden and expense," he said.

Auchenbach cautioned that not all patients should stop therapy, and that if patients do interrupt therapy, they should consult their physician.

Achenbach's co-researchers were Michele Till, M.D., assistant professor of medicine; Sophia Terp; Maria Deloria Knoll, M.D., research assistant professor of preventive medicine; Laura Colangelo; Kiang Liu, professor of preventive medicine; Frank Palella, M.D., assistant professor of medicine; Aleks Kalnins; and Robert L. Murphy, M.D., professor of medicine and director of HIV/AIDS clinical research at Northwestern University.


Story Source:

The above story is based on materials provided by Northwestern University. Note: Materials may be edited for content and length.


Cite This Page:

Northwestern University. "Long-Term Interruption Of HIV Treatment May Be Safe In Certain Patients." ScienceDaily. ScienceDaily, 10 July 2002. <www.sciencedaily.com/releases/2002/07/020710081035.htm>.
Northwestern University. (2002, July 10). Long-Term Interruption Of HIV Treatment May Be Safe In Certain Patients. ScienceDaily. Retrieved March 3, 2015 from www.sciencedaily.com/releases/2002/07/020710081035.htm
Northwestern University. "Long-Term Interruption Of HIV Treatment May Be Safe In Certain Patients." ScienceDaily. www.sciencedaily.com/releases/2002/07/020710081035.htm (accessed March 3, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Tuesday, March 3, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Mom Triumphs Over Tragedy, Helps Other Families

Mom Triumphs Over Tragedy, Helps Other Families

AP (Mar. 3, 2015) After her son, Dax, died from a rare form of leukemia, Julie Locke decided to give back to the doctors at St. Jude Children&apos;s Research Hospital who tried to save his life. She raised $1.6M to help other patients and their families. (March 3) Video provided by AP
Powered by NewsLook.com
Woman Convicted of Poisoning Son

Woman Convicted of Poisoning Son

AP (Mar. 3, 2015) A woman who blogged for years about her son&apos;s constant health woes was convicted Monday of poisoning him to death by force-feeding heavy concentrations of sodium through his stomach tube. (March 3) Video provided by AP
Powered by NewsLook.com
Treadmill Test Can Predict Chance Of Death Within A Decade

Treadmill Test Can Predict Chance Of Death Within A Decade

Newsy (Mar. 2, 2015) Johns Hopkins researchers analyzed 58,000 heart stress tests to come up with a formula that predicts a person&apos;s chances of dying in the next decade. Video provided by Newsy
Powered by NewsLook.com
Going Gluten-Free Could Get You A Tax Break

Going Gluten-Free Could Get You A Tax Break

Newsy (Mar. 2, 2015) If a doctor advises you to remove gluten from your diet, you could get a tax deduction on the amount you spend on gluten-free foods. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins